product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
TRADD Antibody
catalog :
3694
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunoprecipitation, flow cytometry
citations: 30
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; fig 4
He M, Wang M, Huang Y, Peng W, Zheng Z, Xia N, et al. The ORF3 Protein of Genotype 1 Hepatitis E Virus Suppresses TLR3-induced NF-κB Signaling via TRADD and RIP1. Sci Rep. 2016;6:27597 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 4
  • western blot; scFv; loading ...; fig 4b
Li J, Chen K, Li S, Liu T, Wang F, Xia Y, et al. Pretreatment with Fucoidan from Fucus vesiculosus Protected against ConA-Induced Acute Liver Injury by Inhibiting Both Intrinsic and Extrinsic Apoptosis. PLoS ONE. 2016;11:e0152570 pubmed publisher
Stope M, Klinkmann G, Diesing K, Koensgen D, Burchardt M, Mustea A. Heat Shock Protein HSP27 Secretion by Ovarian Cancer Cells Is Linked to Intracellular Expression Levels, Occurs Independently of the Endoplasmic Reticulum Pathway and HSP27's Phosphorylation Status, and Is Mediated by Exosome Liberation. Dis Markers. 2017;2017:1575374 pubmed publisher
Guo X, Yin H, Chen Y, Li L, Li J, Liu Q. TAK1 regulates caspase 8 activation and necroptotic signaling via multiple cell death checkpoints. Cell Death Dis. 2016;7:e2381 pubmed publisher
Juwono J, Martinus R. Does Hsp60 Provide a Link between Mitochondrial Stress and Inflammation in Diabetes Mellitus?. J Diabetes Res. 2016;2016:8017571 pubmed publisher
Papp T, Polyak A, Papp K, Mészár Z, Zákány R, Meszar Katona E, et al. Modification of tooth development by heat shock protein 60. Int J Oral Sci. 2016;8:24-31 pubmed publisher
Sarkar S, Leo B, Carranza C, Chen S, Rivas Santiago C, Porter A, et al. Modulation of Human Macrophage Responses to Mycobacterium tuberculosis by Silver Nanoparticles of Different Size and Surface Modification. PLoS ONE. 2015;10:e0143077 pubmed publisher
Roveri A, Zaccarin M, Pagetta A, Tramentozzi E, Finotti P. Proteomic Investigation on Grp94-IgG Complexes Circulating in Plasma of Type 1 Diabetic Subjects. J Diabetes Res. 2015;2015:815839 pubmed publisher
Arcaro A, Daga M, Cetrangolo G, Ciamporcero E, Lepore A, Pizzimenti S, et al. Generation of Adducts of 4-Hydroxy-2-nonenal with Heat Shock 60 kDa Protein 1 in Human Promyelocytic HL-60 and Monocytic THP-1 Cell Lines. Oxid Med Cell Longev. 2015;2015:296146 pubmed publisher
Thuringer D, Berthenet K, Cronier L, Jego G, Solary E, Garrido C. Oncogenic extracellular HSP70 disrupts the gap-junctional coupling between capillary cells. Oncotarget. 2015;6:10267-83 pubmed
Krause M, Heck T, Bittencourt A, Scomazzon S, Newsholme P, Curi R, et al. The chaperone balance hypothesis: the importance of the extracellular to intracellular HSP70 ratio to inflammation-driven type 2 diabetes, the effect of exercise, and the implications for clinical management. Mediators Inflamm. 2015;2015:249205 pubmed publisher
Tulapurkar M, Ramarathnam A, Hasday J, Singh I. Bacterial lipopolysaccharide augments febrile-range hyperthermia-induced heat shock protein 70 expression and extracellular release in human THP1 cells. PLoS ONE. 2015;10:e0118010 pubmed publisher
Chang C, Chou W, Lin H, Huang Y, Tang L, Lin M, et al. Exercise preconditioning protects against spinal cord injury in rats by upregulating neuronal and astroglial heat shock protein 72. Int J Mol Sci. 2014;15:19018-36 pubmed publisher
Wang H, Tan M, Lu R, Yu J, Tan L. Heat shock proteins at the crossroads between cancer and Alzheimer's disease. Biomed Res Int. 2014;2014:239164 pubmed publisher
Tatsuta T, Sugawara S, Takahashi K, Ogawa Y, Hosono M, Nitta K. Leczyme: a new candidate drug for cancer therapy. Biomed Res Int. 2014;2014:421415 pubmed publisher
Cheng C, Lin J, Tang N, Kao S, Hsieh C. Electroacupuncture-like stimulation at the Baihui (GV20) and Dazhui (GV14) acupoints protects rats against subacute-phase cerebral ischemia-reperfusion injuries by reducing S100B-mediated neurotoxicity. PLoS ONE. 2014;9:e91426 pubmed publisher
Briassoulis G, Briassouli E, Fitrolaki D, Plati I, Apostolou K, Tavladaki T, et al. Heat shock protein 72 expressing stress in sepsis: unbridgeable gap between animal and human studies--a hypothetical "comparative" study. Biomed Res Int. 2014;2014:101023 pubmed publisher
Tatsuta T, Hosono M, Ogawa Y, Inage K, Sugawara S, Nitta K. Downregulation of Hsp70 inhibits apoptosis induced by sialic acid-binding lectin (leczyme). Oncol Rep. 2014;31:13-8 pubmed publisher
Hoshino T, Suzuki K, Matsushima T, Yamakawa N, Suzuki T, Mizushima T. Suppression of Alzheimer's disease-related phenotypes by geranylgeranylacetone in mice. PLoS ONE. 2013;8:e76306 pubmed publisher
Brenu E, Staines D, Tajouri L, Huth T, Ashton K, Marshall Gradisnik S. Heat shock proteins and regulatory T cells. Autoimmune Dis. 2013;2013:813256 pubmed publisher
Popiel H, Takeuchi T, Fujita H, Yamamoto K, Ito C, Yamane H, et al. Hsp40 gene therapy exerts therapeutic effects on polyglutamine disease mice via a non-cell autonomous mechanism. PLoS ONE. 2012;7:e51069 pubmed publisher
Campanella C, Bucchieri F, Merendino A, Fucarino A, Burgio G, Corona D, et al. The odyssey of Hsp60 from tumor cells to other destinations includes plasma membrane-associated stages and Golgi and exosomal protein-trafficking modalities. PLoS ONE. 2012;7:e42008 pubmed publisher
Fábián T, Hermann P, BECK A, Fejerdy P, Fabian G. Salivary defense proteins: their network and role in innate and acquired oral immunity. Int J Mol Sci. 2012;13:4295-320 pubmed publisher
Klink M, Nowak M, Kielbik M, Bednarska K, Blus E, Szpakowski M, et al. The interaction of HspA1A with TLR2 and TLR4 in the response of neutrophils induced by ovarian cancer cells in vitro. Cell Stress Chaperones. 2012;17:661-74 pubmed publisher
Zhang X, Wang X, Zhu H, Kranias E, Tang Y, Peng T, et al. Hsp20 functions as a novel cardiokine in promoting angiogenesis via activation of VEGFR2. PLoS ONE. 2012;7:e32765 pubmed publisher
D Agostino L, Giordano A. A novel dual signaling axis for NSP 5a3a induced apoptosis in head and neck carcinoma. Oncotarget. 2011;2:1055-74 pubmed
van Eden W, Spiering R, Broere F, van der Zee R. A case of mistaken identity: HSPs are no DAMPs but DAMPERs. Cell Stress Chaperones. 2012;17:281-92 pubmed publisher
Anand P, Anand E, Bleck C, Anes E, Griffiths G. Exosomal Hsp70 induces a pro-inflammatory response to foreign particles including mycobacteria. PLoS ONE. 2010;5:e10136 pubmed publisher
Beckmann S, Buro C, Dissous C, Hirzmann J, Grevelding C. The Syk kinase SmTK4 of Schistosoma mansoni is involved in the regulation of spermatogenesis and oogenesis. PLoS Pathog. 2010;6:e1000769 pubmed publisher
Merendino A, Bucchieri F, Campanella C, Marciano V, Ribbene A, David S, et al. Hsp60 is actively secreted by human tumor cells. PLoS ONE. 2010;5:e9247 pubmed publisher
product information
SKU :
3694S
Product-Name :
TRADD Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Flow cytometry
Product-Category :
Apoptosis
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
34
Host :
Rabbit
Target :
TRADD
Primary-Protein :
TRADD
Alt-Names :
Hs.89862,MGC11078,TNFR1-associated DEATH domain protein,TNFRSF1A-associated via death domain,TRADD,Tumor necrosis factor receptor type 1-associated DEATH domain protein,tumor necrosis factor receptor type 1 associated death domain protein,tumor necrosis factor receptor-1-associated protein
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.