product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-Myosin Light Chain 2 (Ser19) Mouse mAb
catalog :
3675S
quantity :
100 ul
price :
274 USD
clonality :
monoclonal
host :
mouse
antigen modification :
phosphorylated
reactivity :
human, mouse, rat, dog, cow, zebrafish
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 18
Published Application/Species/DilutionReference
  • immunocytochemistry; human; 1:100; fig 5
Guen V, Gamble C, Perez D, Bourassa S, Zappel H, Gartner J, et al. STAR syndrome-associated CDK10/Cyclin M regulates actin network architecture and ciliogenesis. Cell Cycle. 2016;15:678-88 pubmed publisher
  • immunocytochemistry; human; 1:50; fig 3
Dorland Y, Malinova T, van Stalborch A, Grieve A, van Geemen D, Jansen N, et al. The F-BAR protein pacsin2 inhibits asymmetric VE-cadherin internalization from tensile adherens junctions. Nat Commun. 2016;7:12210 pubmed publisher
  • immunohistochemistry - frozen section; zebrafish; 1:25; fig 7
Raman R, Damle I, Rote R, Banerjee S, Dingare C, Sonawane M. aPKC regulates apical localization of Lgl to restrict elongation of microridges in developing zebrafish epidermis. Nat Commun. 2016;7:11643 pubmed publisher
  • immunohistochemistry; human; fig 2c
  • immunohistochemistry; mouse; fig 2c
  • western blot; mouse; fig 2b
Lainé A, Martin B, Luka M, Mir L, Auffray C, Lucas B, et al. Foxo1 Is a T Cell-Intrinsic Inhibitor of the RORγt-Th17 Program. J Immunol. 2015;195:1791-803 pubmed publisher
  • western blot; mouse; fig 2b
  • immunohistochemistry; human; fig 2c
  • immunohistochemistry; mouse; fig 2c
Kim J, Lee G, Won Y, Lee M, Kwak J, Chun C, et al. Matrix cross-linking-mediated mechanotransduction promotes posttraumatic osteoarthritis. Proc Natl Acad Sci U S A. 2015;112:9424-9 pubmed publisher
  • immunocytochemistry; mouse; fig s3
Acton S, Farrugia A, Astarita J, Mourão-Sá D, Jenkins R, Nye E, et al. Dendritic cells control fibroblastic reticular network tension and lymph node expansion. Nature. 2014;514:498-502 pubmed publisher
  • western blot; human; fig 6
Menhofer M, Bartel D, Liebl J, Kubisch R, Busse J, Wagner E, et al. In vitro and in vivo characterization of the actin polymerizing compound chondramide as an angiogenic inhibitor. Cardiovasc Res. 2014;104:303-14 pubmed publisher
  • western blot; mouse
Wang Y, Zhao W, Zhang L, Zhao Y, Li F, Zhang Z, et al. Molecular and cellular basis of the regulation of lymphatic contractility and lymphatic absorption. Int J Biochem Cell Biol. 2014;53:134-40 pubmed publisher
  • immunocytochemistry; dog
Tokuda S, Higashi T, Furuse M. ZO-1 knockout by TALEN-mediated gene targeting in MDCK cells: involvement of ZO-1 in the regulation of cytoskeleton and cell shape. PLoS ONE. 2014;9:e104994 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Yuan Y, Yeh L, Liu H, Yamanaka O, Hardie W, Kao W, et al. Targeted overexpression of TGF-α in the corneal epithelium of adult transgenic mice induces changes in anterior segment morphology and activates noncanonical Wnt signaling. Invest Ophthalmol Vis Sci. 2013;54:1829-37 pubmed publisher
  • immunocytochemistry; human
Ma M, Chircop M. SNX9, SNX18 and SNX33 are required for progression through and completion of mitosis. J Cell Sci. 2012;125:4372-82 pubmed publisher
Simamura E, Arikawa T, Ikeda T, Shimada H, Shoji H, Masuta H, et al. Melanocortins contribute to sequential differentiation and enucleation of human erythroblasts via melanocortin receptors 1, 2 and 5. PLoS ONE. 2015;10:e0123232 pubmed publisher
Ma P, Foote D, Sinnamon A, Brass L. Dissociation of SHP-1 from spinophilin during platelet activation exposes an inhibitory binding site for protein phosphatase-1 (PP1). PLoS ONE. 2015;10:e0119496 pubmed publisher
Tripathi B, Lowy D, Zelenka P. The Cdk5 activator P39 specifically links muskelin to myosin II and regulates stress fiber formation and actin organization in lens. Exp Cell Res. 2015;330:186-98 pubmed publisher
Hu J, Niu M, Li X, Lu D, Cui J, Xu W, et al. FERM domain-containing protein FRMD5 regulates cell motility via binding to integrin β5 subunit and ROCK1. FEBS Lett. 2014;588:4348-56 pubmed publisher
Yue X, Yang X, Lin X, Yang T, Yi X, Dai Y, et al. Rnd3 haploinsufficient mice are predisposed to hemodynamic stress and develop apoptotic cardiomyopathy with heart failure. Cell Death Dis. 2014;5:e1284 pubmed publisher
Yamauchi S, Kawauchi K, Sawada Y. Myosin II-dependent exclusion of CD45 from the site of Fcγ receptor activation during phagocytosis. FEBS Lett. 2012;586:3229-35 pubmed publisher
Watanabe T, Hosoya H, Yonemura S. Regulation of myosin II dynamics by phosphorylation and dephosphorylation of its light chain in epithelial cells. Mol Biol Cell. 2007;18:605-16 pubmed
product information
SKU :
3675S
Product-Name :
Phospho-Myosin Light Chain 2 (Ser19) Mouse mAb
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R, B, Pg
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Cytoskeletal Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
18
Host :
Mouse
Target :
Myosin Light Chain 2 (Ser20) phosphate
Primary-Protein :
MRLC1
Alt-Names :
20 kDa myosin light chain,LC20,MGC3505,MLC-2C,MLC2,MRLC1,MYL9,MYRL2,Myosin RLC,Myosin regulatory light chain 2, smooth muscle isoform,Myosin regulatory light chain 9,Myosin regulatory light chain MRLC1,Myosin regulatory light polypeptide 9,myosin regulatory light chain 1,myosin, light chain 9, regulatory,myosin, light polypeptide 9, regulatory
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.