| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; mouse; 1:1000; loading ...; fig 1e
| Gan C, Zou Y, Xia Y, Zhang T, Chen D, Lan G, et al. Inhibition of Death-associated Protein Kinase 1 protects against Epileptic Seizures in mice. Int J Biol Sci. 2021;17:2356-2366 pubmed publisher |
- immunocytochemistry; mouse; 1:50; loading ...; fig 4g
- western blot; mouse; 1:500; loading ...; fig 4f
| Jungwirth U, van Weverwijk A, Evans R, Jenkins L, Vicente D, Alexander J, et al. Impairment of a distinct cancer-associated fibroblast population limits tumour growth and metastasis. Nat Commun. 2021;12:3516 pubmed publisher |
- western blot; human; loading ...; fig 2a
- western blot; mouse; 1:500; loading ...; fig 1e
| Zhang Z, Zhang L, Zhang Q, Liu B, Li F, Xin Y, et al. HO-1/CO Maintains Intestinal Barrier Integrity through NF-κB/MLCK Pathway in Intestinal HO-1-/- Mice. Oxid Med Cell Longev. 2021;2021:6620873 pubmed publisher |
- western blot; rat; fig 3d
| Zhuan B, Wang X, Wang M, Li Z, Yuan Q, Xie J, et al. Hypoxia induces pulmonary artery smooth muscle dysfunction through mitochondrial fragmentation-mediated endoplasmic reticulum stress. Aging (Albany NY). 2020;12:23684-23697 pubmed publisher |
- immunocytochemistry; human; 1:200; loading ...
- western blot; human; 1:200; loading ...
| Wen X, Wan J, He Q, Wang M, Li S, Jiang M, et al. p190A inactivating mutations cause aberrant RhoA activation and promote malignant transformation via the Hippo-YAP pathway in endometrial cancer. Signal Transduct Target Ther. 2020;5:81 pubmed publisher |
- immunohistochemistry; rat; 1:50; loading ...
| Aaltonen N, Singha P, Jakupović H, Wirth T, Samaranayake H, Pasonen Seppänen S, et al. High-Resolution Confocal Fluorescence Imaging of Serine Hydrolase Activity in Cryosections - Application to Glioma Brain Unveils Activity Hotspots Originating from Tumor-Associated Neutrophils. Biol Proced Online. 2020;22:6 pubmed publisher |
- immunocytochemistry; mouse; 1:200; loading ...; fig 6h
| Mason D, Collins J, Dawahare J, Nguyen T, Lin Y, Voytik Harbin S, et al. YAP and TAZ limit cytoskeletal and focal adhesion maturation to enable persistent cell motility. J Cell Biol. 2019;218:1369-1389 pubmed publisher |
- immunocytochemistry; dogs; 1:200; fig s7f
- immunocytochemistry; human; 1:200; loading ...; fig s7e
| Ibar C, Kirichenko E, Keepers B, Enners E, Fleisch K, Irvine K. Tension-dependent regulation of mammalian Hippo signaling through LIMD1. J Cell Sci. 2018;131: pubmed publisher |
- immunohistochemistry; human; loading ...; fig 2b
| Lin Y, Zhen Y, Chien K, Lee I, Lin W, Chen M, et al. LIMCH1 regulates nonmuscle myosin-II activity and suppresses cell migration. Mol Biol Cell. 2017;28:1054-1065 pubmed publisher |
- immunocytochemistry; human; 1:100; loading ...; fig s1f
| Priya R, Liang X, Teo J, Duszyc K, Yap A, Gomez G. ROCK1 but not ROCK2 contributes to RhoA signaling and NMIIA-mediated contractility at the epithelial zonula adherens. Mol Biol Cell. 2017;28:12-20 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 4b
| Platet N, Hinkel I, Richert L, Murdamoothoo D, Moufok Sadoun A, Vanier M, et al. The tumor suppressor CDX2 opposes pro-metastatic biomechanical modifications of colon cancer cells through organization of the actin cytoskeleton. Cancer Lett. 2017;386:57-64 pubmed publisher |
- western blot; rat; 1:1000; loading ...; fig 1c
| Scotcher J, Prysyazhna O, Boguslavskyi A, Kistamás K, Hadgraft N, Martin E, et al. Disulfide-activated protein kinase G I? regulates cardiac diastolic relaxation and fine-tunes the Frank-Starling response. Nat Commun. 2016;7:13187 pubmed publisher |
- immunohistochemistry - paraffin section; human; loading ...; fig 4g
| Coburn L, Lopez H, Caldwell B, Moussa E, Yap C, Priya R, et al. Contact inhibition of locomotion and mechanical cross-talk between cell-cell and cell-substrate adhesion determine the pattern of junctional tension in epithelial cell aggregates. Mol Biol Cell. 2016;27:3436-3448 pubmed |
- immunocytochemistry; human; 1:50; fig 3
| Dorland Y, Malinova T, van Stalborch A, Grieve A, van Geemen D, Jansen N, et al. The F-BAR protein pacsin2 inhibits asymmetric VE-cadherin internalization from tensile adherens junctions. Nat Commun. 2016;7:12210 pubmed publisher |
- immunohistochemistry - frozen section; zebrafish ; 1:25; fig 7
| Raman R, Damle I, Rote R, Banerjee S, Dingare C, Sonawane M. aPKC regulates apical localization of Lgl to restrict elongation of microridges in developing zebrafish epidermis. Nat Commun. 2016;7:11643 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 9b
| Sharanek A, Burban A, Burbank M, Le Guevel R, Li R, Guillouzo A, et al. Rho-kinase/myosin light chain kinase pathway plays a key role in the impairment of bile canaliculi dynamics induced by cholestatic drugs. Sci Rep. 2016;6:24709 pubmed publisher |
- immunocytochemistry; human; 1:100; fig 5
| Guen V, Gamble C, Perez D, Bourassa S, Zappel H, Gartner J, et al. STAR syndrome-associated CDK10/Cyclin M regulates actin network architecture and ciliogenesis. Cell Cycle. 2016;15:678-88 pubmed publisher |
- western blot; mouse; 1:1000; fig 4
| Yuan X, Cao J, He X, Serra R, Qu J, Cao X, et al. Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation. Nat Commun. 2016;7:11024 pubmed publisher |
- immunohistochemistry; mouse; 1:300; fig 7
| Jimeno D, Gómez C, Calzada N, de la Villa P, Lillo C, Santos E. RASGRF2 controls nuclear migration in postnatal retinal cone photoreceptors. J Cell Sci. 2016;129:729-42 pubmed publisher |
- western blot; mouse; 1:1000; fig 2a
| Zhang X, Zhang T, Gao F, Li Q, Shen C, Li Y, et al. Fasudil, a Rho‑kinase inhibitor, prevents intima‑media thickening in a partially ligated carotid artery mouse model: Effects of fasudil in flow‑induced vascular remodeling. Mol Med Rep. 2015;12:7317-25 pubmed publisher |
- western blot; human; 1:500; loading ...; fig 5f
| Caporali A, Meloni M, Nailor A, Mitić T, Shantikumar S, Riu F, et al. p75(NTR)-dependent activation of NF-κB regulates microRNA-503 transcription and pericyte-endothelial crosstalk in diabetes after limb ischaemia. Nat Commun. 2015;6:8024 pubmed publisher |
- immunohistochemistry; human; fig 2c
- immunohistochemistry; mouse; fig 2c
- western blot; mouse; fig 2b
| Lainé A, Martin B, Luka M, Mir L, Auffray C, Lucas B, et al. Foxo1 Is a T Cell-Intrinsic Inhibitor of the RORγt-Th17 Program. J Immunol. 2015;195:1791-803 pubmed publisher |
- immunohistochemistry; mouse; fig 2c
- western blot; mouse; fig 2b
- immunohistochemistry; human; fig 2c
| Kim J, Lee G, Won Y, Lee M, Kwak J, Chun C, et al. Matrix cross-linking-mediated mechanotransduction promotes posttraumatic osteoarthritis. Proc Natl Acad Sci U S A. 2015;112:9424-9 pubmed publisher |
- immunocytochemistry; mouse; fig s3
| Acton S, Farrugia A, Astarita J, Mourão Sá D, Jenkins R, Nye E, et al. Dendritic cells control fibroblastic reticular network tension and lymph node expansion. Nature. 2014;514:498-502 pubmed publisher |
- western blot; human; fig 6
| Menhofer M, Bartel D, Liebl J, Kubisch R, Busse J, Wagner E, et al. In vitro and in vivo characterization of the actin polymerizing compound chondramide as an angiogenic inhibitor. Cardiovasc Res. 2014;104:303-14 pubmed publisher |
- immunocytochemistry; dogs
| Tokuda S, Higashi T, Furuse M. ZO-1 knockout by TALEN-mediated gene targeting in MDCK cells: involvement of ZO-1 in the regulation of cytoskeleton and cell shape. PLoS ONE. 2014;9:e104994 pubmed publisher |
| Wang Y, Zhao W, Zhang L, Zhao Y, Li F, Zhang Z, et al. Molecular and cellular basis of the regulation of lymphatic contractility and lymphatic absorption. Int J Biochem Cell Biol. 2014;53:134-40 pubmed publisher |
- immunohistochemistry - paraffin section; mouse
| Yuan Y, Yeh L, Liu H, Yamanaka O, Hardie W, Kao W, et al. Targeted overexpression of TGF-? in the corneal epithelium of adult transgenic mice induces changes in anterior segment morphology and activates noncanonical Wnt signaling. Invest Ophthalmol Vis Sci. 2013;54:1829-37 pubmed publisher |
- immunocytochemistry; human
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| Shi X, Wen Z, Wang Y, Liu Y, Shi K, Jiu Y. Feedback-Driven Mechanisms Between Phosphorylated Caveolin-1 and Contractile Actin Assemblies Instruct Persistent Cell Migration. Front Cell Dev Biol. 2021;9:665919 pubmed publisher |
| Townshend R, Shao Y, Wang S, Cortez C, Esfahani S, Spence J, et al. Effect of Cell Spreading on Rosette Formation by Human Pluripotent Stem Cell-Derived Neural Progenitor Cells. Front Cell Dev Biol. 2020;8:588941 pubmed publisher |
| Hino N, Rossetti L, Marín Llauradó A, Aoki K, Trepat X, Matsuda M, et al. ERK-Mediated Mechanochemical Waves Direct Collective Cell Polarization. Dev Cell. 2020;53:646-660.e8 pubmed publisher |
| Nava M, Miroshnikova Y, Biggs L, Whitefield D, Metge F, Boucas J, et al. Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage. Cell. 2020;181:800-817.e22 pubmed publisher |
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| Thestrup M, Caviglia S, Cayuso J, Heyne R, Ahmad R, Hofmeister W, et al. A morphogenetic EphB/EphrinB code controls hepatopancreatic duct formation. Nat Commun. 2019;10:5220 pubmed publisher |
| Dupraz S, Hilton B, Husch A, Santos T, Coles C, Stern S, et al. RhoA Controls Axon Extension Independent of Specification in the Developing Brain. Curr Biol. 2019;29:3874-3886.e9 pubmed publisher |
| Juin A, Spence H, Martin K, McGhee E, Neilson M, Cutiongco M, et al. N-WASP Control of LPAR1 Trafficking Establishes Response to Self-Generated LPA Gradients to Promote Pancreatic Cancer Cell Metastasis. Dev Cell. 2019;51:431-445.e7 pubmed publisher |
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| Wang Y, Shou Z, Fan H, Xu M, Chen Q, Tang Q, et al. Protective effects of oxymatrine against DSS-induced acute intestinal inflammation in mice via blocking the RhoA/ROCK signaling pathway. Biosci Rep. 2019;39: pubmed publisher |
| Chen P, Hsu L, Chang H, Huang T, Yu J, Liao H, et al. Elevated Platelet Galectin-3 and Rho-Associated Protein Kinase Activity Are Associated with Hemodialysis Arteriovenous Shunt Dysfunction among Subjects with Diabetes Mellitus. Biomed Res Int. 2019;2019:8952414 pubmed publisher |
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| Williams K, Cepeda M, Javed S, Searle K, Parkins K, Makela A, et al. Invadopodia are chemosensing protrusions that guide cancer cell extravasation to promote brain tropism in metastasis. Oncogene. 2019;38:3598-3615 pubmed publisher |
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| Zhang C, Wang H, Bao Q, Wang L, Guo T, Chen W, et al. NRF2 promotes breast cancer cell proliferation and metastasis by increasing RhoA/ROCK pathway signal transduction. Oncotarget. 2016;7:73593-73606 pubmed publisher |
| Han J, Yi Y, Li C, Zhang Y, Wang L, Zhao Y, et al. Involvement of Histamine and RhoA/ROCK in Penicillin Immediate Hypersensitivity Reactions. Sci Rep. 2016;6:33192 pubmed publisher |
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| Wang J, Zarbin M, Sugino I, Whitehead I, Townes Anderson E. RhoA Signaling and Synaptic Damage Occur Within Hours in a Live Pig Model of CNS Injury, Retinal Detachment. Invest Ophthalmol Vis Sci. 2016;57:3892-906 pubmed publisher |
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