| Published Application/Species/Dilution | Reference |
|---|
- immunocytochemistry; human; fig 8
| Zhang X, Adderley S, Breslin J. Activation of RhoA, but Not Rac1, Mediates Early Stages of S1P-Induced Endothelial Barrier Enhancement. PLoS ONE. 2016;11:e0155490 pubmed publisher |
- western blot; human; 1:1000; fig s4
- western blot; dog; 1:1000; fig 1
| Tien S, Lee H, Yang Y, Lin M, Chen Y, Chang Z. The Shp2-induced epithelial disorganization defect is reversed by HDAC6 inhibition independent of Cdc42. Nat Commun. 2016;7:10420 pubmed publisher |
- western blot; cow; 1:50; fig 1
| Lampi M, Faber C, Huynh J, Bordeleau F, Zanotelli M, Reinhart-King C. Simvastatin Ameliorates Matrix Stiffness-Mediated Endothelial Monolayer Disruption. PLoS ONE. 2016;11:e0147033 pubmed publisher |
- immunocytochemistry; human; 1:100; fig 6
- immunohistochemistry; mouse; 1:100; fig 6
| Heemskerk N, Schimmel L, Oort C, van Rijssel J, Yin T, Ma B, et al. F-actin-rich contractile endothelial pores prevent vascular leakage during leukocyte diapedesis through local RhoA signalling. Nat Commun. 2016;7:10493 pubmed publisher |
- immunocytochemistry; zebrafish; 1:200; fig s9
| Zhang J, Jiang Z, Liu X, Meng A. Eph/ephrin signaling maintains the boundary of dorsal forerunner cell cluster during morphogenesis of the zebrafish embryonic left-right organizer. Development. 2016;143:2603-15 pubmed publisher |
- western blot; human; 1:1000; fig 1
| Chen P, Qin L, Li G, Tellides G, Simons M. Fibroblast growth factor (FGF) signaling regulates transforming growth factor beta (TGFβ)-dependent smooth muscle cell phenotype modulation. Sci Rep. 2016;6:33407 pubmed publisher |
- western blot; mouse; 1:500; fig s4
| Elosegui-Artola A, Oria R, Chen Y, Kosmalska A, Pérez-González C, Castro N, et al. Mechanical regulation of a molecular clutch defines force transmission and transduction in response to matrix rigidity. Nat Cell Biol. 2016;18:540-8 pubmed publisher |
- western blot; mouse; 1:200; fig 2
| Zhou Z, Tang A, Wong W, Bamezai S, Goddard L, Shenkar R, et al. Cerebral cavernous malformations arise from endothelial gain of MEKK3-KLF2/4 signalling. Nature. 2016;532:122-6 pubmed publisher |
| Clark P, Kim R, Pober J, Kluger M. Tumor necrosis factor disrupts claudin-5 endothelial tight junction barriers in two distinct NF-κB-dependent phases. PLoS ONE. 2015;10:e0120075 pubmed publisher |
- immunocytochemistry; chicken; 1:100; fig 7
| Rozbicki E, Chuai M, Karjalainen A, Song F, Sang H, Martin R, et al. Myosin-II-mediated cell shape changes and cell intercalation contribute to primitive streak formation. Nat Cell Biol. 2015;17:397-408 pubmed publisher |
- immunocytochemistry; human; 1:200
| Breslin J, Zhang X, Worthylake R, Souza-Smith F. Involvement of local lamellipodia in endothelial barrier function. PLoS ONE. 2015;10:e0117970 pubmed publisher |
| Takemoto K, Ishihara S, Mizutani T, Kawabata K, Haga H. Compressive stress induces dephosphorylation of the myosin regulatory light chain via RhoA phosphorylation by the adenylyl cyclase/protein kinase A signaling pathway. PLoS ONE. 2015;10:e0117937 pubmed publisher |
- western blot; human; 1:300
| Iguchi Y, Ishihara S, Uchida Y, Tajima K, Mizutani T, Kawabata K, et al. Filamin B Enhances the Invasiveness of Cancer Cells into 3D Collagen Matrices. Cell Struct Funct. 2015;40:61-7 pubmed publisher |
- western blot; human; fig 1
| Wang S, Cui H, Liu Y, Zhao P, Zhang Y, Fu Z, et al. CD147 promotes Src-dependent activation of Rac1 signaling through STAT3/DOCK8 during the motility of hepatocellular carcinoma cells. Oncotarget. 2015;6:243-57 pubmed |
- immunocytochemistry; human
| Daneshjou N, Sieracki N, van Nieuw Amerongen G, Schwartz M, Komarova Y, Malik A, et al. Rac1 functions as a reversible tension modulator to stabilize VE-cadherin trans-interaction. J Cell Biol. 2015;208:23-32 pubmed publisher |
| Kim K, Ossipova O, Sokol S. Neural crest specification by inhibition of the ROCK/Myosin II pathway. Stem Cells. 2015;33:674-85 pubmed publisher |
| Lim H, Multhaupt H, Couchman J. Cell surface heparan sulfate proteoglycans control adhesion and invasion of breast carcinoma cells. Mol Cancer. 2015;14:15 pubmed publisher |
- immunocytochemistry; rat; 1:200-1:500; fig 2
- western blot; hamsters; 1:200-1:500; fig 2
- western blot; rat; 1:200-1:500; fig 2
| Newell-Litwa K, Badoual M, Asmussen H, Patel H, Whitmore L, Horwitz A. ROCK1 and 2 differentially regulate actomyosin organization to drive cell and synaptic polarity. J Cell Biol. 2015;210:225-42 pubmed publisher |
- immunocytochemistry; human; 1:150
- western blot; human; 1:100-1:300
| Ishihara S, Yasuda M, Ishizu A, Ishikawa M, Shirato H, Haga H. Activating transcription factor 5 enhances radioresistance and malignancy in cancer cells. Oncotarget. 2015;6:4602-14 pubmed |
- immunocytochemistry; human; 1:200
| Toh Y, Xing J, Yu H. Modulation of integrin and E-cadherin-mediated adhesions to spatially control heterogeneity in human pluripotent stem cell differentiation. Biomaterials. 2015;50:87-97 pubmed publisher |
- western blot; mouse; 1:1000
| Luo J, Liang M, Mitch W, Danesh F, Yu M, Cheng J. FSP-1 Impairs the Function of Endothelium Leading to Failure of Arteriovenous Grafts in Diabetic Mice. Endocrinology. 2015;156:2200-10 pubmed publisher |
| Bailon E, Ugarte-Berzal E, Amigo-Jiménez I, Van den Steen P, Opdenakker G, García-Marco J, et al. Overexpression of progelatinase B/proMMP-9 affects migration regulatory pathways and impairs chronic lymphocytic leukemia cell homing to bone marrow and spleen. J Leukoc Biol. 2014;96:185-99 pubmed publisher |
- immunocytochemistry; human; fig 2, 3, 4
| Menhofer M, Bartel D, Liebl J, Kubisch R, Busse J, Wagner E, et al. In vitro and in vivo characterization of the actin polymerizing compound chondramide as an angiogenic inhibitor. Cardiovasc Res. 2014;104:303-14 pubmed publisher |
| Anastasía A, Deinhardt K, Wang S, Martin L, Nichol D, Irmady K, et al. Trkb signaling in pericytes is required for cardiac microvessel stabilization. PLoS ONE. 2014;9:e87406 pubmed publisher |
| Tripathi B, Qian X, Mertins P, Wang D, Papageorge A, Carr S, et al. CDK5 is a major regulator of the tumor suppressor DLC1. J Cell Biol. 2014;207:627-42 pubmed publisher |
- immunocytochemistry; human
| Rubashkin M, Cassereau L, Bainer R, DuFort C, Yui Y, Ou G, et al. Force engages vinculin and promotes tumor progression by enhancing PI3K activation of phosphatidylinositol (3,4,5)-triphosphate. Cancer Res. 2014;74:4597-611 pubmed publisher |
| Akaihata H, Nomiya M, Hata J, Yabe M, Takahashi N, Haga N, et al. Pelvic arterial occlusive disease affects the RhoA/Rho-kinase pathway in bladder smooth muscle. J Urol. 2015;193:706-13 pubmed publisher |
| Zhang J, Dong H, Oqani R, Lin T, Kang J, Jin D. Distinct roles of ROCK1 and ROCK2 during development of porcine preimplantation embryos. Reproduction. 2014;148:99-107 pubmed publisher |
| Elson-Schwab I, Lorentzen A, Marshall C. MicroRNA-200 family members differentially regulate morphological plasticity and mode of melanoma cell invasion. PLoS ONE. 2010;5: pubmed publisher |
| Ponsaerts R, D'hondt C, Bultynck G, Srinivas S, Vereecke J, Himpens B. The myosin II ATPase inhibitor blebbistatin prevents thrombin-induced inhibition of intercellular calcium wave propagation in corneal endothelial cells. Invest Ophthalmol Vis Sci. 2008;49:4816-27 pubmed publisher |
| Watanabe T, Hosoya H, Yonemura S. Regulation of myosin II dynamics by phosphorylation and dephosphorylation of its light chain in epithelial cells. Mol Biol Cell. 2007;18:605-16 pubmed |
| Bhadriraju K, Elliott J, Nguyen M, Plant A. Quantifying myosin light chain phosphorylation in single adherent cells with automated fluorescence microscopy. BMC Cell Biol. 2007;8:43 pubmed |
| Li Z, Wang C, Jiao X, Lu Y, Fu M, Quong A, et al. Cyclin D1 regulates cellular migration through the inhibition of thrombospondin 1 and ROCK signaling. Mol Cell Biol. 2006;26:4240-56 pubmed |
| Beach J, Licate L, Crish J, Egelhoff T. Analysis of the role of Ser1/Ser2/Thr9 phosphorylation on myosin II assembly and function in live cells. BMC Cell Biol. 2011;12:52 pubmed publisher |
