| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunohistochemistry; mouse; 1:200; loading ...; fig 5s1c
- western blot; mouse; 1:1000; loading ...; fig 6f
| Laurin M, Gomez N, Levorse J, Sendoel A, Sribour M, Fuchs E. An RNAi screen unravels the complexities of Rho GTPase networks in skin morphogenesis. elife. 2019;8: pubmed publisher |
- immunohistochemistry; mouse; 1:100; loading ...; fig 4h
| Diéguez Hurtado R, Kato K, Giaimo B, Nieminen Kelhä M, Arf H, Ferrante F, et al. Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes. Nat Commun. 2019;10:2817 pubmed publisher |
- western blot; human; loading ...; fig 2a
| Georgouli M, Herraiz C, Crosas Molist E, Fanshawe B, Maiques O, Perdrix A, et al. Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment. Cell. 2019;176:757-774.e23 pubmed publisher |
- western blot; mouse; fig 5b
| Albrengues J, Shields M, Ng D, Park C, Ambrico A, Poindexter M, et al. Neutrophil extracellular traps produced during inflammation awaken dormant cancer cells in mice. Science. 2018;361: pubmed publisher |
- western blot; mouse; loading ...; fig 7g
| Ge J, Burnier L, Adamopoulou M, Kwa M, Schaks M, Rottner K, et al. RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells. J Biol Chem. 2018;293:9358-9369 pubmed publisher |
- western blot; human; fig 6a
| Unbekandt M, Belshaw S, Bower J, Clarke M, Cordes J, Crighton D, et al. Discovery of Potent and Selective MRCK Inhibitors with Therapeutic Effect on Skin Cancer. Cancer Res. 2018;78:2096-2114 pubmed publisher |
- immunohistochemistry - frozen section; mouse; loading ...; fig 9l
- western blot; mouse; loading ...; fig 9o
| Logan C, Rajakaruna S, Bowen C, Radice G, Robinson M, Menko A. N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis. Dev Biol. 2017;428:118-134 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig s1e
| Tang A, Choi J, Kotzin J, Yang Y, Hong C, Hobson N, et al. Endothelial TLR4 and the microbiome drive cerebral cavernous malformations. Nature. 2017;545:305-310 pubmed publisher |
- immunohistochemistry; human; loading ...; fig 2b
| Lin Y, Zhen Y, Chien K, Lee I, Lin W, Chen M, et al. LIMCH1 regulates nonmuscle myosin-II activity and suppresses cell migration. Mol Biol Cell. 2017;28:1054-1065 pubmed publisher |
- western blot; human; 1:500; loading ...; fig 4g
| Bonan S, Albrengues J, Grasset E, Kuzet S, Nottet N, Bourget I, et al. Membrane-bound ICAM-1 contributes to the onset of proinvasive tumor stroma by controlling acto-myosin contractility in carcinoma-associated fibroblasts. Oncotarget. 2017;8:1304-1320 pubmed publisher |
- western blot; mouse; loading ...; fig 4e
| Prasad A, Ketsawatsomkron P, Nuno D, Koval O, Dibbern M, Venema A, et al. Role of CaMKII in Ang-II-dependent small artery remodeling. Vascul Pharmacol. 2016;87:172-179 pubmed publisher |
- immunocytochemistry; hamsters; loading ...; fig 6a
| Webb B, White K, Grillo Hill B, Schönichen A, Choi C, Barber D. A Histidine Cluster in the Cytoplasmic Domain of the Na-H Exchanger NHE1 Confers pH-sensitive Phospholipid Binding and Regulates Transporter Activity. J Biol Chem. 2016;291:24096-24104 pubmed |
- western blot; human; 1:1000; fig 1
| Chen P, Qin L, Li G, Tellides G, Simons M. Fibroblast growth factor (FGF) signaling regulates transforming growth factor beta (TGF?)-dependent smooth muscle cell phenotype modulation. Sci Rep. 2016;6:33407 pubmed publisher |
- western blot; human; 1:2000; loading ...; fig 3b
| Yuan S, Pardue S, Shen X, Alexander J, Orr A, Kevil C. Hydrogen sulfide metabolism regulates endothelial solute barrier function. Redox Biol. 2016;9:157-166 pubmed publisher |
- western blot; mouse; 1:1000; loading ...
| Jenny Zhou H, Qin L, Zhang H, Tang W, Ji W, He Y, et al. Endothelial exocytosis of angiopoietin-2 resulting from CCM3 deficiency contributes to cerebral cavernous malformation. Nat Med. 2016;22:1033-1042 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:200; loading ...
| Freddo A, Shoffner S, Shao Y, Taniguchi K, Grosse A, Guysinger M, et al. Coordination of signaling and tissue mechanics during morphogenesis of murine intestinal villi: a role for mitotic cell rounding. Integr Biol (Camb). 2016;8:918-28 pubmed publisher |
- immunocytochemistry; zebrafish ; 1:200; fig s9
| Zhang J, Jiang Z, Liu X, Meng A. Eph/ephrin signaling maintains the boundary of dorsal forerunner cell cluster during morphogenesis of the zebrafish embryonic left-right organizer. Development. 2016;143:2603-15 pubmed publisher |
- immunocytochemistry; human; fig 8
| Zhang X, Adderley S, Breslin J. Activation of RhoA, but Not Rac1, Mediates Early Stages of S1P-Induced Endothelial Barrier Enhancement. PLoS ONE. 2016;11:e0155490 pubmed publisher |
- western blot; mouse; 1:500; fig s4
| Elosegui Artola A, Oria R, Chen Y, Kosmalska A, Pérez González C, Castro N, et al. Mechanical regulation of a molecular clutch defines force transmission and transduction in response to matrix rigidity. Nat Cell Biol. 2016;18:540-8 pubmed publisher |
- western blot; mouse; 1:200; fig 2
| Zhou Z, Tang A, Wong W, Bamezai S, Goddard L, Shenkar R, et al. Cerebral cavernous malformations arise from endothelial gain of MEKK3-KLF2/4 signalling. Nature. 2016;532:122-6 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:100; loading ...; fig s4a
- immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig s4a
| Sakar M, Eyckmans J, Pieters R, Eberli D, Nelson B, Chen C. Cellular forces and matrix assembly coordinate fibrous tissue repair. Nat Commun. 2016;7:11036 pubmed publisher |
- western blot; human; fig 4
| Kim D, Helfman D. Loss of MLCK leads to disruption of cell-cell adhesion and invasive behavior of breast epithelial cells via increased expression of EGFR and ERK/JNK signaling. Oncogene. 2016;35:4495-508 pubmed publisher |
- immunohistochemistry; mouse; 1:100; fig 6
- immunocytochemistry; human; 1:100; fig 6
| Heemskerk N, Schimmel L, Oort C, van Rijssel J, Yin T, Ma B, et al. F-actin-rich contractile endothelial pores prevent vascular leakage during leukocyte diapedesis through local RhoA signalling. Nat Commun. 2016;7:10493 pubmed publisher |
- western blot; dogs; 1:1000; fig 1
- western blot; human; 1:1000; fig s4
| Tien S, Lee H, Yang Y, Lin M, Chen Y, Chang Z. The Shp2-induced epithelial disorganization defect is reversed by HDAC6 inhibition independent of Cdc42. Nat Commun. 2016;7:10420 pubmed publisher |
- western blot; bovine; 1:50; fig 1
| Lampi M, Faber C, Huynh J, Bordeleau F, Zanotelli M, Reinhart King C. Simvastatin Ameliorates Matrix Stiffness-Mediated Endothelial Monolayer Disruption. PLoS ONE. 2016;11:e0147033 pubmed publisher |
| Foster C, Gualdrini F, Treisman R. Mutual dependence of the MRTF-SRF and YAP-TEAD pathways in cancer-associated fibroblasts is indirect and mediated by cytoskeletal dynamics. Genes Dev. 2017;31:2361-2375 pubmed publisher |
| Jiu Y, Peranen J, Schaible N, Cheng F, Eriksson J, Krishnan R, et al. Vimentin intermediate filaments control actin stress fiber assembly through GEF-H1 and RhoA. J Cell Sci. 2017;130:892-902 pubmed publisher |
| Rath N, Morton J, Julian L, Helbig L, Kadir S, McGhee E, et al. ROCK signaling promotes collagen remodeling to facilitate invasive pancreatic ductal adenocarcinoma tumor cell growth. EMBO Mol Med. 2017;9:198-218 pubmed publisher |
| Mardakheh F, Self A, Marshall C. RHO binding to FAM65A regulates Golgi reorientation during cell migration. J Cell Sci. 2016;129:4466-4479 pubmed |
| Zhang C, Wang H, Bao Q, Wang L, Guo T, Chen W, et al. NRF2 promotes breast cancer cell proliferation and metastasis by increasing RhoA/ROCK pathway signal transduction. Oncotarget. 2016;7:73593-73606 pubmed publisher |
| Han J, Yi Y, Li C, Zhang Y, Wang L, Zhao Y, et al. Involvement of Histamine and RhoA/ROCK in Penicillin Immediate Hypersensitivity Reactions. Sci Rep. 2016;6:33192 pubmed publisher |
