product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Glucocorticoid Receptor (D8H2) XP® Rabbit mAb
catalog :
3660
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
D8H2
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section
citations: 7
Published Application/Species/Sample/DilutionReference
  • chromatin immunoprecipitation; mouse; loading ...; fig 5a
  • chromatin immunoprecipitation; human; loading ...; fig 5b
Vispute S, Bu P, Le Y, Cheng X. Activation of GR but not PXR by dexamethasone attenuated acetaminophen hepatotoxicities via Fgf21 induction. Toxicology. 2017;378:95-106 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2c
Kassi E, Nasiri Ansari N, Spilioti E, Kalotychou V, Apostolou P, Moutsatsou P, et al. Vitamin D interferes with glucocorticoid responsiveness in human peripheral blood mononuclear target cells. Cell Mol Life Sci. 2016;73:4341-4354 pubmed
  • immunocytochemistry; human; fig s1
Goodman C, Sato T, Peck A, Girondo M, Yang N, Liu C, et al. Steroid induction of therapy-resistant cytokeratin-5-positive cells in estrogen receptor-positive breast cancer through a BCL6-dependent mechanism. Oncogene. 2016;35:1373-85 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 1
Baker G, Murphy T, Block T, Nguyen D, Lynch F. Development and validation of an immunohistochemistry assay to assess glucocorticoid receptor expression for clinical trials of mifepristone in breast cancer. Cancer Manag Res. 2015;7:361-8 pubmed publisher
  • immunocytochemistry; mouse; 1:100; fig 1d
Herbst S, Shah A, Mazon Moya M, Marzola V, Jensen B, Reed A, et al. Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus. EMBO Mol Med. 2015;7:240-58 pubmed publisher
He B, Cruz Topete D, Oakley R, Xiao X, Cidlowski J. Human Glucocorticoid Receptor β Regulates Gluconeogenesis and Inflammation in Mouse Liver. Mol Cell Biol. 2015;36:714-30 pubmed publisher
Sun F, Indran I, Zhang Z, Tan M, Li Y, Lim Z, et al. A novel prostate cancer therapeutic strategy using icaritin-activated arylhydrocarbon-receptor to co-target androgen receptor and its splice variants. Carcinogenesis. 2015;36:757-68 pubmed publisher
product information
SKU :
3660P
Product-Name :
Glucocorticoid Receptor (D8H2) XP® Rabbit mAb
Size :
40 ul
Price-(USD) :
135 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Chromatin Immunoprecipitation
Product-Category :
Nuclear Receptor Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
80, 91, 94
Host :
Rabbit
Target :
Glucocorticoid Receptor
Primary-Protein :
GR
Alt-Names :
GCCR,GCR,GR,GRL,Glucocorticoid receptor,NR3C1,Nuclear receptor subfamily 3 group C member 1,nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.