product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
WAVE-2 (D2C8) XP® Rabbit mAb
catalog :
3659
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
D2C8
reactivity :
Aplysia, human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, proximity ligation assay
more info or order :
Cell Signaling Technology product webpage
citations: 18
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 5d
Chorzalska A, Morgan J, Ahsan N, Treaba D, Olszewski A, Petersen M, et al. Bone marrow-specific loss of ABI1 induces myeloproliferative neoplasm with features resembling human myelofibrosis. Blood. 2018;: pubmed publisher
  • immunocytochemistry; Aplysia; 1:100; fig 4g
Buck K, Schaefer A, Schoonderwoert V, Creamer M, Dufresne E, Forscher P. Local Arp2/3-dependent actin assembly modulates applied traction force during apCAM adhesion site maturation. Mol Biol Cell. 2017;28:98-110 pubmed publisher
  • proximity ligation assay; human; 1:50; fig 5
  • immunocytochemistry; human; 1:50; fig 7
  • western blot; human; 1:1000
Lee N, Fok K, White A, Wilson N, O Leary C, Cox H, et al. Neogenin recruitment of the WAVE regulatory complex maintains adherens junction stability and tension. Nat Commun. 2016;7:11082 pubmed publisher
  • western blot; human; 1:500; fig 3
Tao Y, Hu K, Tan F, Zhang S, Zhou M, Luo J, et al. SH3-domain binding protein 1 in the tumor microenvironment promotes hepatocellular carcinoma metastasis through WAVE2 pathway. Oncotarget. 2016;7:18356-70 pubmed publisher
  • western blot; human; fig 7a
Thomas A, Mariani Floderer C, López Huertas M, Gros N, Hamard Péron E, Favard C, et al. Involvement of the Rac1-IRSp53-Wave2-Arp2/3 Signaling Pathway in HIV-1 Gag Particle Release in CD4 T Cells. J Virol. 2015;89:8162-81 pubmed publisher
  • proximity ligation assay; human; fig s4
  • immunoprecipitation; human; fig 5
  • immunocytochemistry; human; fig 5
  • western blot; human; fig 5
Dugina V, Khromova N, Rybko V, Blizniukov O, Shagieva G, Chaponnier C, et al. Tumor promotion by γ and suppression by β non-muscle actin isoforms. Oncotarget. 2015;6:14556-71 pubmed
  • immunocytochemistry; human
Mooren O, Li J, Nawas J, Cooper J. Endothelial cells use dynamic actin to facilitate lymphocyte transendothelial migration and maintain the monolayer barrier. Mol Biol Cell. 2014;25:4115-29 pubmed publisher
Janjanam J, Chandaka G, Kotla S, Rao G. PLCβ3 mediates cortactin interaction with WAVE2 in MCP1-induced actin polymerization and cell migration. Mol Biol Cell. 2015;26:4589-606 pubmed publisher
Van Itallie C, Tietgens A, Krystofiak E, Kachar B, Anderson J. A complex of ZO-1 and the BAR-domain protein TOCA-1 regulates actin assembly at the tight junction. Mol Biol Cell. 2015;26:2769-87 pubmed publisher
Cheung J, Dickinson D, Moss J, Schuler M, Spellman R, Heard P. Histone markers identify the mode of action for compounds positive in the TK6 micronucleus assay. Mutat Res Genet Toxicol Environ Mutagen. 2015;777:7-16 pubmed publisher
Wu X, Yuan H, Li H, Gong S, Lin J, Miao Y, et al. Restraint stress on female mice diminishes the developmental potential of oocytes: roles of chromatin configuration and histone modification in germinal vesicle stage oocytes. Biol Reprod. 2015;92:13 pubmed publisher
Adell T, Saló E, van Loon J, Auletta G. Planarians sense simulated microgravity and hypergravity. Biomed Res Int. 2014;2014:679672 pubmed publisher
Kuroda S, Tam J, Roth J, Sokolov K, Ramesh R. EGFR-targeted plasmonic magnetic nanoparticles suppress lung tumor growth by abrogating G2/M cell-cycle arrest and inducing DNA damage. Int J Nanomedicine. 2014;9:3825-39 pubmed publisher
Murk K, Blanco Suarez E, Cockbill L, Banks P, Hanley J. The antagonistic modulation of Arp2/3 activity by N-WASP, WAVE2 and PICK1 defines dynamic changes in astrocyte morphology. J Cell Sci. 2013;126:3873-83 pubmed publisher
Zhang Q, Zhai S, Li L, Li X, Zhou H, Liu A, et al. Anti-tumor selectivity of a novel tubulin and HSP90 dual-targeting inhibitor in non-small cell lung cancer models. Biochem Pharmacol. 2013;86:351-60 pubmed publisher
Oike T, Ogiwara H, Torikai K, Nakano T, Yokota J, Kohno T. Garcinol, a histone acetyltransferase inhibitor, radiosensitizes cancer cells by inhibiting non-homologous end joining. Int J Radiat Oncol Biol Phys. 2012;84:815-21 pubmed publisher
Rouhana L, Vieira A, Roberts Galbraith R, Newmark P. PRMT5 and the role of symmetrical dimethylarginine in chromatoid bodies of planarian stem cells. Development. 2012;139:1083-94 pubmed publisher
Wernimont S, Wiemer A, Bennin D, Monkley S, Ludwig T, Critchley D, et al. Contact-dependent T cell activation and T cell stopping require talin1. J Immunol. 2011;187:6256-67 pubmed publisher
product information
SKU :
3659S
Product-Name :
WAVE-2 (D2C8) XP® Rabbit mAb
Size :
100 ul
Price-(USD) :
260 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Cytoskeletal Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
80
Host :
Rabbit
Target :
WAVE2
Primary-Protein :
WAVE2
Alt-Names :
IMD2,Protein WAVE-2,SCAR2,Verprolin homology domain-containing protein 2,WAS protein family, member 2,WASF2,WASP family Verprolin-homologous protein 2,WASP family protein member 2,WAVE2,Wiskott-Aldrich syndrome protein family member 2,dJ393P12.2,suppressor of cyclic-AMP receptor (WASP-family)
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.