product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-Histone H3 (Ser10) (D2C8) XP® Rabbit mAb (Biotinylated)
catalog :
3642
clonality :
monoclonal
host :
rabbit
conjugate :
biotin
antigen modification :
phosphorylated
clone name :
D2C8
reactivity :
human, mouse, rat, fruit fly
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry
citations: 13
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; fruit fly; 1:200; fig 2fs1h
Dey N, Ramesh P, Chugh M, Mandal S, Mandal L. Dpp dependent Hematopoietic stem cells give rise to Hh dependent blood progenitors in larval lymph gland of Drosophila. elife. 2016;5: pubmed publisher
  • western blot; human; fig 5
Xiao J, Duan Q, Wang Z, Yan W, Sun H, Xue P, et al. Phosphorylation of TOPK at Y74, Y272 by Src increases the stability of TOPK and promotes tumorigenesis of colon. Oncotarget. 2016;7:24483-94 pubmed publisher
  • western blot; human; loading ...; fig 5b
Preet R, Siddharth S, Satapathy S, Das S, Nayak A, Das D, et al. Chk1 inhibitor synergizes quinacrine mediated apoptosis in breast cancer cells by compromising the base excision repair cascade. Biochem Pharmacol. 2016;105:23-33 pubmed publisher
  • flow cytometry; human; fig s5
Abu Odeh M, Hereema N, Aqeilan R. WWOX modulates the ATR-mediated DNA damage checkpoint response. Oncotarget. 2016;7:4344-55 pubmed publisher
Bulusu V, Prior N, Snaebjornsson M, Kuehne A, Sonnen K, Kress J, et al. Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development. Dev Cell. 2017;40:331-341.e4 pubmed publisher
Kovatcheva M, Liu D, Dickson M, Klein M, O Connor R, Wilder F, et al. MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition. Oncotarget. 2015;6:8226-43 pubmed
Cheung J, Dickinson D, Moss J, Schuler M, Spellman R, Heard P. Histone markers identify the mode of action for compounds positive in the TK6 micronucleus assay. Mutat Res Genet Toxicol Environ Mutagen. 2015;777:7-16 pubmed publisher
Wu X, Yuan H, Li H, Gong S, Lin J, Miao Y, et al. Restraint stress on female mice diminishes the developmental potential of oocytes: roles of chromatin configuration and histone modification in germinal vesicle stage oocytes. Biol Reprod. 2015;92:13 pubmed publisher
Adell T, Saló E, van Loon J, Auletta G. Planarians sense simulated microgravity and hypergravity. Biomed Res Int. 2014;2014:679672 pubmed publisher
Kuroda S, Tam J, Roth J, Sokolov K, Ramesh R. EGFR-targeted plasmonic magnetic nanoparticles suppress lung tumor growth by abrogating G2/M cell-cycle arrest and inducing DNA damage. Int J Nanomedicine. 2014;9:3825-39 pubmed publisher
Zhang Q, Zhai S, Li L, Li X, Zhou H, Liu A, et al. Anti-tumor selectivity of a novel tubulin and HSP90 dual-targeting inhibitor in non-small cell lung cancer models. Biochem Pharmacol. 2013;86:351-60 pubmed publisher
Oike T, Ogiwara H, Torikai K, Nakano T, Yokota J, Kohno T. Garcinol, a histone acetyltransferase inhibitor, radiosensitizes cancer cells by inhibiting non-homologous end joining. Int J Radiat Oncol Biol Phys. 2012;84:815-21 pubmed publisher
Rouhana L, Vieira A, Roberts Galbraith R, Newmark P. PRMT5 and the role of symmetrical dimethylarginine in chromatoid bodies of planarian stem cells. Development. 2012;139:1083-94 pubmed publisher
product information
SKU :
3642S
Product-Name :
Phospho-Histone H3 (Ser10) (D2C8) XP® Rabbit mAb (Biotinylated)
Size :
100 ul
Price-(USD) :
321 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Flow cytometry
Product-Category :
Chromatin Regulation / Nuclear Function
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
17
Host :
Rabbit
Target :
H3 (Ser11) phosphate
Primary-Protein :
H3
Alt-Names :
H3 histone family, member A,H3/A,H31,H3FA,H3FB,H3FC,H3FD,H3FF,H3FH,H3FI,H3FJ,H3FK,H3FL,HIST1H3A,HIST1H3B,HIST1H3C,HIST1H3D,HIST1H3E,HIST1H3F,HIST1H3G,HIST1H3H,HIST1H3I,HIST1H3J,Histone H3.1,Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l,histone 1, H3a,histone cluster 1, H3a
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.