| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; 1:1000; loading ...; fig 4a
| Pavlova N, King B, Josselsohn R, Violante S, Macera V, Vardhana S, et al. Translation in amino-acid-poor environments is limited by tRNAGln charging. elife. 2020;9: pubmed publisher |
- western blot; human; loading ...; fig s5b
| Miyazaki T, Zhao Z, Ichihara Y, Yoshino D, Imamura T, Sawada K, et al. Mechanical regulation of bone homeostasis through p130Cas-mediated alleviation of NF-κB activity. Sci Adv. 2019;5:eaau7802 pubmed publisher |
- western blot; human; loading ...; fig ex4b
| Parolia A, Cieslik M, Chu S, Xiao L, Ouchi T, Zhang Y, et al. Distinct structural classes of activating FOXA1 alterations in advanced prostate cancer. Nature. 2019;: pubmed publisher |
- western blot; mouse; loading ...; fig 4b
| Fursova N, Blackledge N, Nakayama M, Ito S, Koseki Y, Farcas A, et al. Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression. Mol Cell. 2019;74:1020-1036.e8 pubmed publisher |
- western blot; mouse; loading ...; fig 5c
| Chorzalska A, Morgan J, Ahsan N, Treaba D, Olszewski A, Petersen M, et al. Bone marrow-specific loss of ABI1 induces myeloproliferative neoplasm with features resembling human myelofibrosis. Blood. 2018;: pubmed publisher |
- western blot; mouse; 1:2500; loading ...; fig s6g
| Liu Z, Qin Q, Wu C, Li H, Shou J, Yang Y, et al. Downregulated NDR1 protein kinase inhibits innate immune response by initiating an miR146a-STAT1 feedback loop. Nat Commun. 2018;9:2789 pubmed publisher |
- western blot; mouse; 1:2000; loading ...; fig 8g
| Hsu J, Xia W, Hsu Y, Chan L, Yu W, Cha J, et al. STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion. Nat Commun. 2018;9:1908 pubmed publisher |
- western blot; human; loading ...; fig 3b
| Pleiner T, Bates M, Gorlich D. A toolbox of anti-mouse and anti-rabbit IgG secondary nanobodies. J Cell Biol. 2018;217:1143-1154 pubmed publisher |
- western blot; human; loading ...; fig 8e
| Patne K, Rakesh R, Arya V, Chanana U, Sethy R, Swer P, et al. BRG1 and SMARCAL1 transcriptionally co-regulate DROSHA, DGCR8 and DICER in response to doxorubicin-induced DNA damage. Biochim Biophys Acta Gene Regul Mech. 2017;1860:936-951 pubmed publisher |
- western blot; human; loading ...; fig 1c
| Mahajan K, Malla P, Lawrence H, Chen Z, Kumar Sinha C, Malik R, et al. ACK1/TNK2 Regulates Histone H4 Tyr88-phosphorylation and AR Gene Expression in Castration-Resistant Prostate Cancer. Cancer Cell. 2017;31:790-803.e8 pubmed publisher |
- western blot; mouse; loading ...; fig 5
| Jha K, Tripurani S, Johnson G. TSSK6 is required for γH2AX formation and the histone-to-protamine transition during spermiogenesis. J Cell Sci. 2017;130:1835-1844 pubmed publisher |
- western blot; human; 1:1000; tbl s6
| Mair B, Konopka T, Kerzendorfer C, Sleiman K, Salic S, Serra V, et al. Gain- and Loss-of-Function Mutations in the Breast Cancer Gene GATA3 Result in Differential Drug Sensitivity. PLoS Genet. 2016;12:e1006279 pubmed publisher |
- western blot; human; loading ...; fig 1b
| Ueda T, Nakata Y, Nagamachi A, Yamasaki N, Kanai A, Sera Y, et al. Propagation of trimethylated H3K27 regulated by polycomb protein EED is required for embryogenesis, hematopoietic maintenance, and tumor suppression. Proc Natl Acad Sci U S A. 2016;113:10370-5 pubmed publisher |
- western blot; human; 1:1000; fig 1
| Iimori M, Watanabe S, Kiyonari S, Matsuoka K, Sakasai R, Saeki H, et al. Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability. Nat Commun. 2016;7:11117 pubmed publisher |
- western blot; mouse; fig 4
| Nikonova A, Deneka A, Eckman L, Kopp M, Hensley H, Egleston B, et al. Opposing Effects of Inhibitors of Aurora-A and EGFR in Autosomal-Dominant Polycystic Kidney Disease. Front Oncol. 2015;5:228 pubmed publisher |
- western blot; mouse; 1:1000
| Meraviglia V, Azzimato V, Colussi C, Florio M, Binda A, Panariti A, et al. Acetylation mediates Cx43 reduction caused by electrical stimulation. J Mol Cell Cardiol. 2015;87:54-64 pubmed publisher |
- western blot; mouse; 1:1000
| Tyler C, Hafez A, Solomon E, Allan A. Developmental exposure to 50 parts-per-billion arsenic influences histone modifications and associated epigenetic machinery in a region- and sex-specific manner in the adult mouse brain. Toxicol Appl Pharmacol. 2015;288:40-51 pubmed publisher |
- western blot; human; 1:20,000
| Knutson S, Warholic N, Johnston L, Klaus C, Wigle T, Iwanowicz D, et al. Synergistic Anti-Tumor Activity of EZH2 Inhibitors and Glucocorticoid Receptor Agonists in Models of Germinal Center Non-Hodgkin Lymphomas. PLoS ONE. 2014;9:e111840 pubmed publisher |
- western blot; human; 1:1000; fig 1
| Hashizume R, Andor N, Ihara Y, Lerner R, Gan H, Chen X, et al. Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma. Nat Med. 2014;20:1394-6 pubmed publisher |
| Tafrova J, Tafrov S. Human histone acetyltransferase 1 (Hat1) acetylates lysine 5 of histone H2A in vivo. Mol Cell Biochem. 2014;392:259-72 pubmed publisher |
| Zhao J, Yue W, Zhu M, Du M. AMP-activated protein kinase regulates beta-catenin transcription via histone deacetylase 5. J Biol Chem. 2011;286:16426-34 pubmed publisher |
- western blot; human; 1:20,000
| Sneeringer C, Scott M, Kuntz K, Knutson S, Pollock R, Richon V, et al. Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas. Proc Natl Acad Sci U S A. 2010;107:20980-5 pubmed publisher |
| Fukuda K, Shimura C, Miura H, Tanigawa A, Suzuki T, Dohmae N, et al. Regulation of mammalian 3D genome organization and histone H3K9 dimethylation by H3K9 methyltransferases. Commun Biol. 2021;4:571 pubmed publisher |
| Kramer D, Aisenberg E, Kosillo P, Friedmann D, Stafford D, Lee A, et al. Generation of a DAT-P2A-Flpo mouse line for intersectional genetic targeting of dopamine neuron subpopulations. Cell Rep. 2021;35:109123 pubmed publisher |
| Xiang C, Frietze K, Bi Y, Li Y, Dal Pozzo V, Pal S, et al. RP58 Represses Transcriptional Programs Linked to Nonneuronal Cell Identity and Glioblastoma Subtypes in Developing Neurons. Mol Cell Biol. 2021;41:e0052620 pubmed publisher |
| Parsels L, Engelke C, Parsels J, Flanagan S, Zhang Q, Tanska D, et al. Combinatorial Efficacy of Olaparib with Radiation and ATR Inhibitor Requires PARP1 Protein in Homologous Recombination-Proficient Pancreatic Cancer. Mol Cancer Ther. 2021;20:263-273 pubmed publisher |
| Akpa C, Kleo K, Oker E, Tomaszewski N, Messerschmidt C, Lopez C, et al. Acquired resistance to DZNep-mediated apoptosis is associated with copy number gains of AHCY in a B-cell lymphoma model. BMC Cancer. 2020;20:427 pubmed publisher |
| Blackledge N, Fursova N, Kelley J, Huseyin M, Feldmann A, Klose R. PRC1 Catalytic Activity Is Central to Polycomb System Function. Mol Cell. 2019;: pubmed publisher |
| Pefani D, Tognoli M, Pirincci Ercan D, Gorgoulis V, O Neill E. MST2 kinase suppresses rDNA transcription in response to DNA damage by phosphorylating nucleolar histone H2B. EMBO J. 2018;37: pubmed publisher |
| Fu Q, Chen K, Zhu Q, Wang W, Huang F, Miao L, et al. ?-catenin promotes intracellular bacterial killing via suppression of Pseudomonas aeruginosa-triggered macrophage autophagy. J Int Med Res. 2017;45:556-569 pubmed publisher |
| McGrath J, Williamson K, Balasubramanian S, Odate S, Arora S, Hatton C, et al. Pharmacological Inhibition of the Histone Lysine Demethylase KDM1A Suppresses the Growth of Multiple Acute Myeloid Leukemia Subtypes. Cancer Res. 2016;76:1975-88 pubmed publisher |
| McGonigle S, Chen Z, Wu J, Chang P, Kolber Simonds D, Ackermann K, et al. E7449: A dual inhibitor of PARP1/2 and tankyrase1/2 inhibits growth of DNA repair deficient tumors and antagonizes Wnt signaling. Oncotarget. 2015;6:41307-23 pubmed publisher |
| Barsotti A, Ryskin M, Zhong W, Zhang W, Giannakou A, Loreth C, et al. Epigenetic reprogramming by tumor-derived EZH2 gain-of-function mutations promotes aggressive 3D cell morphologies and enhances melanoma tumor growth. Oncotarget. 2015;6:2928-38 pubmed |
| Lehmann M, Hoffmann M, Koch A, Ulrich S, Schulz W, Niegisch G. Histone deacetylase 8 is deregulated in urothelial cancer but not a target for efficient treatment. J Exp Clin Cancer Res. 2014;33:59 pubmed publisher |
| Farg M, Sundaramoorthy V, Sultana J, Yang S, Atkinson R, Levina V, et al. C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking. Hum Mol Genet. 2014;23:3579-95 pubmed publisher |
| Lutz M, Milenkovic I, Regelsberger G, Kovacs G. Distinct patterns of sirtuin expression during progression of Alzheimer's disease. Neuromolecular Med. 2014;16:405-14 pubmed publisher |
| Wells C, Bhaskara S, Stengel K, Zhao Y, Sirbu B, Chagot B, et al. Inhibition of histone deacetylase 3 causes replication stress in cutaneous T cell lymphoma. PLoS ONE. 2013;8:e68915 pubmed publisher |
| Ivanov A, Pawlikowski J, Manoharan I, van Tuyn J, Nelson D, Rai T, et al. Lysosome-mediated processing of chromatin in senescence. J Cell Biol. 2013;202:129-43 pubmed publisher |
