product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
MCM2 (D7G11) XP® Rabbit mAb
catalog :
3619
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
D7G11
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, chromatin immunoprecipitation, immunohistochemistry - paraffin section
citations: 10
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig s2a
Utani K, Fu H, Jang S, Marks A, Smith O, Zhang Y, et al. Phosphorylated SIRT1 associates with replication origins to prevent excess replication initiation and preserve genomic stability. Nucleic Acids Res. 2017;45:7807-7824 pubmed publisher
  • western blot; human; loading ...; fig 6e
Hong S, Eun J, Choi S, Shen Q, Choi W, Han J, et al. Epigenetic reader BRD4 inhibition as a therapeutic strategy to suppress E2F2-cell cycle regulation circuit in liver cancer. Oncotarget. 2016;7:32628-40 pubmed publisher
  • western blot; mouse; loading ...; fig s7e
Su K, Cao J, Tang Z, Dai S, He Y, Sampson S, et al. HSF1 critically attunes proteotoxic stress sensing by mTORC1 to combat stress and promote growth. Nat Cell Biol. 2016;18:527-39 pubmed publisher
  • western blot; human; fig 7
Graindorge D, Martineau S, Machon C, Arnoux P, Guitton J, Francesconi S, et al. Singlet Oxygen-Mediated Oxidation during UVA Radiation Alters the Dynamic of Genomic DNA Replication. PLoS ONE. 2015;10:e0140645 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4a
Cao J, Lu Y, Qi J, An G, Mao Z, Jia H, et al. MiR-630 inhibits proliferation by targeting CDC7 kinase, but maintains the apoptotic balance by targeting multiple modulators in human lung cancer A549 cells. Cell Death Dis. 2014;5:e1426 pubmed publisher
  • flow cytometry; mouse
Marshall G, Deleyrolle L, Reynolds B, Steindler D, Laywell E. Microglia from neurogenic and non-neurogenic regions display differential proliferative potential and neuroblast support. Front Cell Neurosci. 2014;8:180 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:400
Kawabata K, Tung N, Shoyama Y, Sugie S, Mori T, Tanaka T. Dietary Crocin Inhibits Colitis and Colitis-Associated Colorectal Carcinogenesis in Male ICR Mice. Evid Based Complement Alternat Med. 2012;2012:820415 pubmed publisher
Casar Tena T, Maerz L, Szafranski K, Groth M, Blätte T, Donow C, et al. Resting cells rely on the DNA helicase component MCM2 to build cilia. Nucleic Acids Res. 2019;47:134-151 pubmed publisher
Kuno T, Hatano Y, Tomita H, Hara A, Hirose Y, Hirata A, et al. Organomagnesium suppresses inflammation-associated colon carcinogenesis in male Crj: CD-1 mice. Carcinogenesis. 2013;34:361-9 pubmed publisher
Lal A, Thomas M, Altschuler G, Navarro F, O Day E, Li X, et al. Capture of microRNA-bound mRNAs identifies the tumor suppressor miR-34a as a regulator of growth factor signaling. PLoS Genet. 2011;7:e1002363 pubmed publisher
product information
SKU :
3619S
Product-Name :
MCM2 (D7G11) XP® Rabbit mAb
Size :
100 ul
Price-(USD) :
260 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Chromatin Immunoprecipitation
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
125
Host :
Rabbit
Target :
MCM2
Primary-Protein :
MCM2
Alt-Names :
BM28,CCNL1,CDCL1,D3S3194,DNA replication licensing factor MCM2,KIAA0030,MCM2,MCM2 minichromosome maintenance deficient 2, mitotin,MGC10606,MITOTIN,Minichromosome maintenance protein 2 homolog,Nuclear protein BM28,cdc19,cell devision cycle-like 1,cyclin-like 1,minichromosome maintenance complex component 2,minichromosome maintenance deficient 2 (mitotin)
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.