product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Notch1 (D1E11) XP® Rabbit mAb
catalog :
3608S
quantity :
100 ul
price :
260 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
Cell Signaling Technology product webpage
citations: 13
Published Application/Species/DilutionReference
  • western blot; human; 1:1000; fig 6
Fan C, Jia L, Zheng Y, Jin C, Liu Y, Liu H, et al. MiR-34a Promotes Osteogenic Differentiation of Human Adipose-Derived Stem Cells via the RBP2/NOTCH1/CYCLIN D1 Coregulatory Network. Stem Cell Reports. 2016;7:236-48 pubmed publisher
  • western blot; human; fig 6
Noh H, Hah Y, Ha J, Kang M, Zada S, Rha S, et al. Regulation of the epithelial to mesenchymal transition and metastasis by Raf kinase inhibitory protein-dependent Notch1 activity. Oncotarget. 2016;7:4632-46 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:25
Jäger W, Xue H, Hayashi T, Janssen C, Awrey S, Wyatt A, et al. Patient-derived bladder cancer xenografts in the preclinical development of novel targeted therapies. Oncotarget. 2015;6:21522-32 pubmed
  • western blot; human; fig f4
  • western blot; mouse; fig f6
Yang L, Zhang S, George S, Teng R, You X, Xu M, et al. Targeting Notch1 and proteasome as an effective strategy to suppress T-cell lymphoproliferative neoplasms. Oncotarget. 2015;6:14953-69 pubmed
  • immunohistochemistry; human; 1:100
El Hindy N, Keyvani K, Pagenstecher A, Dammann P, Sandalcioglu I, Sure U, et al. Implications of Dll4-Notch signaling activation in primary glioblastoma multiforme. Neuro Oncol. 2013;15:1366-78 pubmed publisher
  • immunohistochemistry - paraffin section; human
  • immunohistochemistry - paraffin section; rat
Yoshida R, Nagata M, Nakayama H, Niimori-Kita K, Hassan W, Tanaka T, et al. The pathological significance of Notch1 in oral squamous cell carcinoma. Lab Invest. 2013;93:1068-81 pubmed publisher
  • immunohistochemistry - paraffin section; human; 0.7 ug/ml
Sundlisaeter E, Edelmann R, Hol J, Sponheim J, Küchler A, WEISS M, et al. The alarmin IL-33 is a notch target in quiescent endothelial cells. Am J Pathol. 2012;181:1099-111 pubmed publisher
Matulic M, Skelin J, Radić-Kristo D, Kardum-Skelin I, Grcevic D, Antica M. Notch affects the prodifferentiating effect of retinoic acid and PMA on leukemic cells. Cytometry A. 2015;87:129-36 pubmed publisher
Hagenbeek T, Wu X, Choy L, Sanchez-Irizarry C, Seshagiri S, Stinson J, et al. Murine Pten(-/-) T-ALL requires non-redundant PI3K/mTOR and DLL4/Notch1 signals for maintenance and γc/TCR signals for thymic exit. Cancer Lett. 2014;346:237-48 pubmed publisher
Harjes U, Bridges E, McIntyre A, Fielding B, Harris A. Fatty acid-binding protein 4, a point of convergence for angiogenic and metabolic signaling pathways in endothelial cells. J Biol Chem. 2014;289:23168-76 pubmed publisher
Fujiki K, Inamura H, Matsuoka M. Detrimental effects of Notch1 signaling activated by cadmium in renal proximal tubular epithelial cells. Cell Death Dis. 2014;5:e1378 pubmed publisher
Lombardo Y, Faronato M, Filipovic A, Vircillo V, Magnani L, Coombes R. Nicastrin and Notch4 drive endocrine therapy resistance and epithelial to mesenchymal transition in MCF7 breast cancer cells. Breast Cancer Res. 2014;16:R62 pubmed publisher
Choi P, van Riggelen J, Gentles A, Bachireddy P, Rakhra K, Adam S, et al. Lymphomas that recur after MYC suppression continue to exhibit oncogene addiction. Proc Natl Acad Sci U S A. 2011;108:17432-7 pubmed publisher
product information
SKU :
3608S
Product-Name :
Notch1 (D1E11) XP® Rabbit mAb
Size :
100 ul
Price-(USD) :
260 USD
Species-x-Reactivity :
H, M, R
Applications :
Chromatin Immunoprecipitation
Product-Category :
Developmental Biology
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
120, 300
Host :
Rabbit
Target :
Notch1
Primary-Protein :
Notch 1
Alt-Names :
NOTC1,NOTCH1,Neurogenic locus notch homolog protein 1,Notch 1,Notch 1 extracellular truncation,Notch 1 intracellular domain,Notch homolog 1, translocation-associated (Drosophila),TAN1,Translocation-associated notch protein TAN-1,hN1
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.