product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-LAT (Tyr191) Antibody
catalog :
3584
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human, mouse
application :
western blot, immunocytochemistry, immunoprecipitation
citations: 9
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 7c
Zhao X, Sankaran S, Yap J, Too C, Ho Z, Dolton G, et al. Nonstimulatory peptide-MHC enhances human T-cell antigen-specific responses by amplifying proximal TCR signaling. Nat Commun. 2018;9:2716 pubmed publisher
  • immunocytochemistry; human; fig s12
Yi J, Manna A, Barr V, Hong J, Neuman K, Samelson L. madSTORM: a superresolution technique for large-scale multiplexing at single-molecule accuracy. Mol Biol Cell. 2016;27:3591-3600 pubmed
  • western blot; mouse; loading ...; fig 3e
Naik E, Dixit V. Usp9X Is Required for Lymphocyte Activation and Homeostasis through Its Control of ZAP70 Ubiquitination and PKCβ Kinase Activity. J Immunol. 2016;196:3438-51 pubmed publisher
  • western blot; mouse; fig 5
Hu H, Wang H, Xiao Y, Jin J, Chang J, Zou Q, et al. Otud7b facilitates T cell activation and inflammatory responses by regulating Zap70 ubiquitination. J Exp Med. 2016;213:399-414 pubmed publisher
  • western blot; human; fig 2
Vivar O, Masi G, Carpier J, Magalhaes J, Galgano D, Pazour G, et al. IFT20 controls LAT recruitment to the immune synapse and T-cell activation in vivo. Proc Natl Acad Sci U S A. 2016;113:386-91 pubmed publisher
  • western blot; human; fig 4
Klammt C, Novotná L, Li D, Wolf M, Blount A, Zhang K, et al. T cell receptor dwell times control the kinase activity of Zap70. Nat Immunol. 2015;16:961-9 pubmed publisher
Markwart R, Condotta S, Requardt R, Borken F, Schubert K, Weigel C, et al. Immunosuppression after sepsis: systemic inflammation and sepsis induce a loss of naïve T-cells but no enduring cell-autonomous defects in T-cell function. PLoS ONE. 2014;9:e115094 pubmed publisher
Verhagen A, de Graaf C, Baldwin T, Goradia A, Collinge J, Kile B, et al. Reduced lymphocyte longevity and homeostatic proliferation in lamin B receptor-deficient mice results in profound and progressive lymphopenia. J Immunol. 2012;188:122-34 pubmed publisher
Álvarez Errico D, Oliver Vila I, Ainsua Enrich E, Gilfillan A, Picado C, Sayós J, et al. CD84 negatively regulates IgE high-affinity receptor signaling in human mast cells. J Immunol. 2011;187:5577-86 pubmed publisher
product information
SKU :
3584S
Product-Name :
Phospho-LAT (Tyr191) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H
Applications :
Immunoprecipitation
Product-Category :
Immunology and Inflammation
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
36, 38
Host :
Rabbit
Target :
LAT (Tyr220) phosphate
Primary-Protein :
LAT
Alt-Names :
36 kDa phospho-tyrosine adapter protein,36 kDa phospho-tyrosine adaptor protein,LAT,LAT1,Linker for activation of T-cells family member 1,linker for activation of T cells,p36-38,pp36
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.