| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunocytochemistry; human; 1:100; loading ...; fig s1c
| Elhussieny A, Nogami K, Sakai Takemura F, Maruyama Y, Takemura N, Soliman W, et al. Mesenchymal stem cells derived from human induced pluripotent stem cells improve the engraftment of myogenic cells by secreting urokinase-type plasminogen activator receptor (uPAR). Stem Cell Res Ther. 2021;12:532 pubmed publisher |
- immunocytochemistry; human; 1:50; loading ...; fig 3a
- western blot; human; 1:500; loading ...; fig 3b
| Generali M, Satheesha S, Bode P, Wanner D, Schafer B, Casanova E. High Frequency of Tumor Propagating Cells in Fusion-Positive Rhabdomyosarcoma. Genes (Basel). 2021;12: pubmed publisher |
- western blot; human; 1:1000; fig 4b
| Lo Cascio C, McNamara J, Melendez E, Lewis E, Dufault M, Sanai N, et al. Nonredundant, isoform-specific roles of HDAC1 in glioma stem cells. JCI Insight. 2021;6: pubmed publisher |
- western blot; human; 1:1000; fig 7g
| Yin H, Wang J, Li H, Yu Y, Wang X, Lu L, et al. Extracellular matrix protein-1 secretory isoform promotes ovarian cancer through increasing alternative mRNA splicing and stemness. Nat Commun. 2021;12:4230 pubmed publisher |
- immunocytochemistry; human; 1:1000; loading ...; fig 1b
| Calvo Garrido J, Winn D, Maffezzini C, Wedell A, Freyer C, Falk A, et al. Protocol for the derivation, culturing, and differentiation of human iPS-cell-derived neuroepithelial stem cells to study neural differentiation in vitro. STAR Protoc. 2021;2:100528 pubmed publisher |
- immunocytochemistry; human; 1:1000; loading ...; fig 1b
| Yamamura Y, Furuichi K, Murakawa Y, Hirabayashi S, Yoshihara M, Sako K, et al. Identification of candidate PAX2-regulated genes implicated in human kidney development. Sci Rep. 2021;11:9123 pubmed publisher |
- immunocytochemistry; human; fig 3b
| Aban C, Lombardi A, Neiman G, Biani M, La Greca A, Waisman A, et al. Downregulation of E-cadherin in pluripotent stem cells triggers partial EMT. Sci Rep. 2021;11:2048 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 4b
| Lu M, Qin X, Zhou Y, Li G, Liu Z, Geng X, et al. Long non-coding RNA LINC00665 promotes gemcitabine resistance of Cholangiocarcinoma cells via regulating EMT and stemness properties through miR-424-5p/BCL9L axis. Cell Death Dis. 2021;12:72 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 4b
| Li W, Zhang N, Jin C, Long M, Rajabi H, Yasumizu Y, et al. MUC1-C drives stemness in progression of colitis to colorectal cancer. JCI Insight. 2020;5: pubmed publisher |
- immunocytochemistry; mouse; loading ...; fig 7a
| Gunne Braden A, Sullivan A, Gharibi B, Sheriff R, Maity A, Wang Y, et al. GATA3 Mediates a Fast, Irreversible Commitment to BMP4-Driven Differentiation in Human Embryonic Stem Cells. Cell Stem Cell. 2020;26:693-706.e9 pubmed publisher |
- western blot; human; loading ...; fig 5a
| Chen J, Chen S, Zhuo L, Zhu Y, Zheng H. Regulation of cancer stem cell properties, angiogenesis, and vasculogenic mimicry by miR-450a-5p/SOX2 axis in colorectal cancer. Cell Death Dis. 2020;11:173 pubmed publisher |
- western blot; human; fig 1d
| Chandrasekaran B, Dahiya N, Tyagi A, Kolluru V, Saran U, Baby B, et al. Chronic exposure to cadmium induces a malignant transformation of benign prostate epithelial cells. Oncogenesis. 2020;9:23 pubmed publisher |
- immunocytochemistry; human; 1:400; fig s3a
| Rahman M, Wruck W, Spitzhorn L, Nguyen L, Bohndorf M, Martins S, et al. The FGF, TGFβ and WNT axis Modulate Self-renewal of Human SIX2+ Urine Derived Renal Progenitor Cells. Sci Rep. 2020;10:739 pubmed publisher |
- western blot; mouse; loading ...; fig 5c
| Zhan Y, Li R, Feng C, Li X, Huang S, Wang L, et al. Chlorogenic acid inhibits esophageal squamous cell carcinoma growth in vitro and in vivo by downregulating the expression of BMI1 and SOX2. Biomed Pharmacother. 2020;121:109602 pubmed publisher |
- immunohistochemistry; mouse; loading ...; fig 4c
| Kim G, Rincon Fernandez Pacheco D, Saxon D, Yang A, Sabet S, Dutra Clarke M, et al. Rapid Generation of Somatic Mouse Mosaics with Locus-Specific, Stably Integrated Transgenic Elements. Cell. 2019;179:251-267.e24 pubmed publisher |
- western blot; human; loading ...; fig 3a
| Sin Chan P, Mumal I, Suwal T, Ho B, Fan X, Singh I, et al. A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor. Cancer Cell. 2019;36:51-67.e7 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 5f
| Lin Q, Li S, Jiang N, Shao X, Zhang M, Jin H, et al. PINK1-parkin pathway of mitophagy protects against contrast-induced acute kidney injury via decreasing mitochondrial ROS and NLRP3 inflammasome activation. Redox Biol. 2019;26:101254 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig s1g
| Sonego M, Pellarin I, Costa A, Vinciguerra G, Coan M, Kraut A, et al. USP1 links platinum resistance to cancer cell dissemination by regulating Snail stability. Sci Adv. 2019;5:eaav3235 pubmed publisher |
- western blot; human; loading ...; fig 5a
| Wang Z, Feng X, Molinolo A, Martin D, Vitale Cross L, Nohata N, et al. 4E-BP1 Is a Tumor Suppressor Protein Reactivated by mTOR Inhibition in Head and Neck Cancer. Cancer Res. 2019;: pubmed publisher |
- immunocytochemistry; human; 1:100; loading ...; fig 4a
- immunohistochemistry; human; 1:200; loading ...; fig 8b
- western blot; human; 1:1000; loading ...; fig 4h
| Wang J, Xu S, Duan J, Yi L, Guo Y, Shi Y, et al. Invasion of white matter tracts by glioma stem cells is regulated by a NOTCH1-SOX2 positive-feedback loop. Nat Neurosci. 2019;22:91-105 pubmed publisher |
- immunohistochemistry; human; 1:250; fig 1c
| Weltner J, Balboa D, Katayama S, Bespalov M, Krjutskov K, Jouhilahti E, et al. Human pluripotent reprogramming with CRISPR activators. Nat Commun. 2018;9:2643 pubmed publisher |
- immunohistochemistry; human; 1:160; loading ...; fig 5c
| Kogut I, McCarthy S, Pavlova M, Astling D, Chen X, Jakimenko A, et al. High-efficiency RNA-based reprogramming of human primary fibroblasts. Nat Commun. 2018;9:745 pubmed publisher |
- immunocytochemistry; human; fig 5g
| Wu X, Dao Thi V, Huang Y, Billerbeck E, Saha D, Hoffmann H, et al. Intrinsic Immunity Shapes Viral Resistance of Stem Cells. Cell. 2018;172:423-438.e25 pubmed publisher |
- immunocytochemistry; human; loading ...; fig 3b
| Jin L, Vu T, Yuan G, Datta P. STRAP Promotes Stemness of Human Colorectal Cancer via Epigenetic Regulation of the NOTCH Pathway. Cancer Res. 2017;77:5464-5478 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 2a
- immunocytochemistry; human; 1:200; loading ...; fig 3h
| Shi Y, Ping Y, Zhou W, He Z, Chen C, Bian B, et al. Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth. Nat Commun. 2017;8:15080 pubmed publisher |
- immunohistochemistry - paraffin section; human; fig 6b
- immunocytochemistry; human; loading ...; fig 2c
- western blot; human; loading ...; fig 2a
| Yoon C, Cho S, Chang K, Park D, Ryeom S, Yoon S. Role of Rac1 Pathway in Epithelial-to-Mesenchymal Transition and Cancer Stem-like Cell Phenotypes in Gastric Adenocarcinoma. Mol Cancer Res. 2017;15:1106-1116 pubmed publisher |
- immunocytochemistry; human; fig 3b
| Bharathan S, Manian K, Aalam S, Palani D, Deshpande P, Pratheesh M, et al. Systematic evaluation of markers used for the identification of human induced pluripotent stem cells. Biol Open. 2017;6:100-108 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 3b
| Xiao Y, Ma H, Wan P, Qin D, Wang X, Zhang X, et al. Trp-Asp (WD) Repeat Domain 1 Is Essential for Mouse Peri-implantation Development and Regulates Cofilin Phosphorylation. J Biol Chem. 2017;292:1438-1448 pubmed publisher |
- immunohistochemistry - frozen section; human; 1:500; loading ...; fig s1b
- western blot; human; 1:1000; loading ...; fig 2f
| Katsushima K, Natsume A, Ohka F, Shinjo K, Hatanaka A, Ichimura N, et al. Targeting the Notch-regulated non-coding RNA TUG1 for glioma treatment. Nat Commun. 2016;7:13616 pubmed publisher |
- western blot; human; loading ...; fig 2c
| Sareddy G, Viswanadhapalli S, Surapaneni P, Suzuki T, Brenner A, Vadlamudi R. Novel KDM1A inhibitors induce differentiation and apoptosis of glioma stem cells via unfolded protein response pathway. Oncogene. 2017;36:2423-2434 pubmed publisher |
- immunocytochemistry; human; 1:400; fig s10b
| Zeltner N, Fattahi F, Dubois N, Saurat N, Lafaille F, Shang L, et al. Capturing the biology of disease severity in a PSC-based model of familial dysautonomia. Nat Med. 2016;22:1421-1427 pubmed publisher |
- western blot; human; 1:1000; fig 2
| Lee E, Wang J, Yumoto K, Jung Y, Cackowski F, Decker A, et al. DNMT1 Regulates Epithelial-Mesenchymal Transition and Cancer Stem Cells, Which Promotes Prostate Cancer Metastasis. Neoplasia. 2016;18:553-66 pubmed publisher |
- western blot; human; loading ...; fig 5e
| Lv D, Yu S, Ping Y, Wu H, Zhao X, Zhang H, et al. A three-dimensional collagen scaffold cell culture system for screening anti-glioma therapeutics. Oncotarget. 2016;7:56904-56914 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 2c
| Mansouri S, Singh S, Alamsahebpour A, Burrell K, Li M, Karabork M, et al. DICER governs characteristics of glioma stem cells and the resulting tumors in xenograft mouse models of glioblastoma. Oncotarget. 2016;7:56431-56446 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 1d
| Pinet S, Bessette B, Vedrenne N, Lacroix A, Richard L, Jauberteau M, et al. TrkB-containing exosomes promote the transfer of glioblastoma aggressiveness to YKL-40-inactivated glioblastoma cells. Oncotarget. 2016;7:50349-50364 pubmed publisher |
- immunocytochemistry; human; 1:400; fig 2
| Francis K, Ton A, Xin Y, O Halloran P, Wassif C, Malik N, et al. Modeling Smith-Lemli-Opitz syndrome with induced pluripotent stem cells reveals a causal role for Wnt/β-catenin defects in neuronal cholesterol synthesis phenotypes. Nat Med. 2016;22:388-96 pubmed publisher |
- immunohistochemistry - frozen section; human; fig 1d
- western blot; human; 1:1000; fig 1c
| Ren C, Ren T, Yang K, Wang S, Bao X, Zhang F, et al. Inhibition of SOX2 induces cell apoptosis and G1/S arrest in Ewing's sarcoma through the PI3K/Akt pathway. J Exp Clin Cancer Res. 2016;35:44 pubmed publisher |
- western blot; human; loading ...; fig 1c
| Xu M, Bian S, Li J, He J, Chen H, Ge L, et al. MeCP2 suppresses LIN28A expression via binding to its methylated-CpG islands in pancreatic cancer cells. Oncotarget. 2016;7:14476-85 pubmed publisher |
- immunocytochemistry; human; 1:500; loading ...; fig 1e
| Balboa D, Weltner J, Eurola S, Trokovic R, Wartiovaara K, Otonkoski T. Conditionally Stabilized dCas9 Activator for Controlling Gene Expression in Human Cell Reprogramming and Differentiation. Stem Cell Reports. 2015;5:448-59 pubmed publisher |
- western blot; mouse; loading ...; fig 1a
- western blot; human; loading ...; fig 5d
| Bora Singhal N, Perumal D, Nguyen J, Chellappan S. Gli1-Mediated Regulation of Sox2 Facilitates Self-Renewal of Stem-Like Cells and Confers Resistance to EGFR Inhibitors in Non-Small Cell Lung Cancer. Neoplasia. 2015;17:538-51 pubmed publisher |
- immunohistochemistry; dogs; 1:50; fig 2
| Kegler K, Spitzbarth I, Imbschweiler I, Wewetzer K, Baumgärtner W, Seehusen F. Contribution of Schwann Cells to Remyelination in a Naturally Occurring Canine Model of CNS Neuroinflammation. PLoS ONE. 2015;10:e0133916 pubmed publisher |
- immunocytochemistry; human; 1:400; fig 3
- western blot; human; 1:1000; fig 4
| Zucha M, Wu A, Lee W, Wang L, Lin W, Yuan C, et al. Bruton's tyrosine kinase (Btk) inhibitor ibrutinib suppresses stem-like traits in ovarian cancer. Oncotarget. 2015;6:13255-68 pubmed |
- immunocytochemistry; human; loading ...; fig s4d
| Di Cristofori A, Ferrero S, Bertolini I, Gaudioso G, Russo M, Berno V, et al. The vacuolar H+ ATPase is a novel therapeutic target for glioblastoma. Oncotarget. 2015;6:17514-31 pubmed |
- western blot; human; 1:500; loading ...; fig 1
| Jung K, Gupta N, Wang P, Lewis J, Gopal K, Wu F, et al. Triple negative breast cancers comprise a highly tumorigenic cell subpopulation detectable by its high responsiveness to a Sox2 regulatory region 2 (SRR2) reporter. Oncotarget. 2015;6:10366-73 pubmed |
- immunocytochemistry; human; fig 1
| Ma R, Latif R, Davies T. Human embryonic stem cells form functional thyroid follicles. Thyroid. 2015;25:455-61 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:100; tbl 2
| Weissferdt A, Rodriguez Canales J, Liu H, Fujimoto J, Wistuba I, Moran C. Primary mediastinal seminomas: a comprehensive immunohistochemical study with a focus on novel markers. Hum Pathol. 2015;46:376-83 pubmed publisher |
- immunocytochemistry; human; 1:250
| Muchkaeva I, Dashinimaev E, Artyuhov A, Myagkova E, Vorotelyak E, Yegorov Y, et al. Generation of iPS Cells from Human Hair Follice Dermal Papilla Cells. Acta Naturae. 2014;6:45-53 pubmed |
- western blot; human; 1:1000; fig 1c
| Mouallif M, Albert A, Zeddou M, Ennaji M, Delvenne P, Guenin S. Expression profile of undifferentiated cell transcription factor 1 in normal and cancerous human epithelia. Int J Exp Pathol. 2014;95:251-9 pubmed publisher |
| Liu H, Zhang W, Jia Y, Yu Q, Grau G, Peng L, et al. Single-cell clones of liver cancer stem cells have the potential of differentiating into different types of tumor cells. Cell Death Dis. 2013;4:e857 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:50
| Mao X, Hütt Cabezas M, Orr B, Weingart M, Taylor I, Rajan A, et al. LIN28A facilitates the transformation of human neural stem cells and promotes glioblastoma tumorigenesis through a pro-invasive genetic program. Oncotarget. 2013;4:1050-64 pubmed |
| Maiti S, Mondal S, Satyavarapu E, Mandal C. mTORC2 regulates hedgehog pathway activity by promoting stability to Gli2 protein and its nuclear translocation. Cell Death Dis. 2017;8:e2926 pubmed publisher |
| Bhargava S, Visvanathan A, Patil V, Kumar A, Kesari S, Das S, et al. IGF2 mRNA binding protein 3 (IMP3) promotes glioma cell migration by enhancing the translation of RELA/p65. Oncotarget. 2017;8:40469-40485 pubmed publisher |
| Wu C, Zhang H, Gupta N, Alshareef A, Wang Q, Huang Y, et al. A positive feedback loop involving the Wnt/?-catenin/MYC/Sox2 axis defines a highly tumorigenic cell subpopulation in ALK-positive anaplastic large cell lymphoma. J Hematol Oncol. 2016;9:120 pubmed |
| Tominaga K, Shimamura T, Kimura N, Murayama T, Matsubara D, Kanauchi H, et al. Addiction to the IGF2-ID1-IGF2 circuit for maintenance of the breast cancer stem-like cells. Oncogene. 2017;36:1276-1286 pubmed publisher |
| Schaefer T, Wang H, Mir P, Konantz M, Pereboom T, Paczulla A, et al. Molecular and functional interactions between AKT and SOX2 in breast carcinoma. Oncotarget. 2015;6:43540-56 pubmed publisher |
| Kang W, Kim S, Cho H, Jin J, Lee J, Joo K, et al. Talin1 targeting potentiates anti-angiogenic therapy by attenuating invasion and stem-like features of glioblastoma multiforme. Oncotarget. 2015;6:27239-51 pubmed publisher |
| Wong H, Fatimy R, Onodera C, Wei Z, Yi M, Mohan A, et al. The Cancer Genome Atlas Analysis Predicts MicroRNA for Targeting Cancer Growth and Vascularization in Glioblastoma. Mol Ther. 2015;23:1234-1247 pubmed publisher |
| Shibuya K, Okada M, Suzuki S, Seino M, Seino S, Takeda H, et al. Targeting the facilitative glucose transporter GLUT1 inhibits the self-renewal and tumor-initiating capacity of cancer stem cells. Oncotarget. 2015;6:651-61 pubmed |
| Miyatake Y, Sheehy N, Ikeshita S, Hall W, Kasahara M. Anchorage-dependent multicellular aggregate formation induces CD44 high cancer stem cell-like ATL cells in an NF-κB- and vimentin-dependent manner. Cancer Lett. 2015;357:355-63 pubmed publisher |
| Sandstrom R, Foret M, Grow D, Haugen E, Rhodes C, Cardona A, et al. Epigenetic regulation by chromatin activation mark H3K4me3 in primate progenitor cells within adult neurogenic niche. Sci Rep. 2014;4:5371 pubmed publisher |
| Yang W, Lee Y, Jones A, Woolnough J, Zhou D, Dai Q, et al. The histone H2A deubiquitinase Usp16 regulates embryonic stem cell gene expression and lineage commitment. Nat Commun. 2014;5:3818 pubmed publisher |
| Huang P, Watanabe M, Kaku H, Ueki H, Noguchi H, Sugimoto M, et al. Cancer stem cell-like characteristics of a CD133+ subpopulation in the J82 human bladder cancer cell line. Mol Clin Oncol. 2013;1:180-184 pubmed |
| Rybak A, Tang D. SOX2 plays a critical role in EGFR-mediated self-renewal of human prostate cancer stem-like cells. Cell Signal. 2013;25:2734-42 pubmed publisher |
| Bareiss P, Paczulla A, Wang H, Schairer R, Wiehr S, Kohlhofer U, et al. SOX2 expression associates with stem cell state in human ovarian carcinoma. Cancer Res. 2013;73:5544-55 pubmed publisher |
| da Cunha J, da Costa Neves A, Kerkis I, da Silva M. Pluripotent stem cell transcription factors during human odontogenesis. Cell Tissue Res. 2013;353:435-41 pubmed publisher |
| Kregel S, Kiriluk K, Rosen A, Cai Y, Reyes E, Otto K, et al. Sox2 is an androgen receptor-repressed gene that promotes castration-resistant prostate cancer. PLoS ONE. 2013;8:e53701 pubmed publisher |
| Katz S, Fisher J, Correll M, Bronson R, Ligon K, Walensky L. Brain and testicular tumors in mice with progenitor cells lacking BAX and BAK. Oncogene. 2013;32:4078-85 pubmed publisher |
| Xu D, Yang C, Proescholdt M, Bründl E, Brawanski A, Fang X, et al. Neuronatin in a subset of glioblastoma multiforme tumor progenitor cells is associated with increased cell proliferation and shorter patient survival. PLoS ONE. 2012;7:e37811 pubmed publisher |
| Polak U, Hirsch C, Ku S, GOTTESFELD J, Dent S, Napierala M. Selecting and isolating colonies of human induced pluripotent stem cells reprogrammed from adult fibroblasts. J Vis Exp. 2012;: pubmed publisher |
| Anaka M, Freyer C, Gedye C, Caballero O, Davis I, Behren A, et al. Stem cell media culture of melanoma results in the induction of a nonrepresentative neural expression profile. Stem Cells. 2012;30:336-43 pubmed publisher |
