product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
CD44 (156-3C11) Mouse mAb
catalog :
3570
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
156-3C11
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, other
citations: 47
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 3a
Pothuraju R, Rachagani S, Krishn S, Chaudhary S, Nimmakayala R, Siddiqui J, et al. Molecular implications of MUC5AC-CD44 axis in colorectal cancer progression and chemoresistance. Mol Cancer. 2020;19:37 pubmed publisher
  • western blot; human; loading ...; fig 5d
Chen Z, Wang H, Wang S, Fan L, Feng S, Cai X, et al. USP9X deubiquitinates ALDH1A3 and maintains mesenchymal identity in glioblastoma stem cells. J Clin Invest. 2019;130:2043-2055 pubmed publisher
  • other; human; loading ...; fig 4c
Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  • immunocytochemistry; human; 1:200; loading ...; fig 4b
Pleiner T, Bates M, Gorlich D. A toolbox of anti-mouse and anti-rabbit IgG secondary nanobodies. J Cell Biol. 2018;217:1143-1154 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 3a
  • western blot; human; loading ...; fig 3c
Sahu U, Choudhury A, Parvez S, Biswas S, Kar S. Induction of intestinal stemness and tumorigenicity by aberrant internalization of commensal non-pathogenic E. coli. Cell Death Dis. 2017;8:e2667 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 5B
Celiku O, Tandle A, Chung J, Hewitt S, Camphausen K, Shankavaram U. Computational analysis of the mesenchymal signature landscape in gliomas. BMC Med Genomics. 2017;10:13 pubmed publisher
  • western blot; human; loading ...; fig 4d
Oh B, Kim S, Lee Y, Hong H, Kim T, Kim S, et al. Twist1-induced epithelial-mesenchymal transition according to microsatellite instability status in colon cancer cells. Oncotarget. 2016;7:57066-57076 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; fig 1
Liu Y, Wang K, Xing H, Zhai X, Wang L, Wang W. Attempt towards a novel classification of triple-negative breast cancer using immunohistochemical markers. Oncol Lett. 2016;12:1240-1256 pubmed
  • immunohistochemistry - paraffin section; human; 1:100; fig 10
Sundararaman A, Amirtham U, Rangarajan A. Calcium-Oxidant Signaling Network Regulates AMP-activated Protein Kinase (AMPK) Activation upon Matrix Deprivation. J Biol Chem. 2016;291:14410-29 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200; tbl 2
Sato K, Suda K, Shimizu S, Sakai K, Mizuuchi H, Tomizawa K, et al. Clinical, Pathological, and Molecular Features of Lung Adenocarcinomas with AXL Expression. PLoS ONE. 2016;11:e0154186 pubmed publisher
  • western blot; human; fig 5
Haraguchi T, Kondo M, Uchikawa R, Kobayashi K, Hiramatsu H, Kobayashi K, et al. Dynamics and plasticity of the epithelial to mesenchymal transition induced by miR-200 family inhibition. Sci Rep. 2016;6:21117 pubmed publisher
  • western blot; human; 1:1000; fig s3
Qiu L, Wu J, Pan C, Tan X, Lin J, Liu R, et al. Downregulation of CDC27 inhibits the proliferation of colorectal cancer cells via the accumulation of p21Cip1/Waf1. Cell Death Dis. 2016;7:e2074 pubmed publisher
  • immunoprecipitation; human; fig 5b
  • western blot; human; fig 5b
Wands A, Fujita A, McCombs J, Cervin J, Dedic B, Rodriguez A, et al. Fucosylation and protein glycosylation create functional receptors for cholera toxin. elife. 2015;4:e09545 pubmed publisher
  • western blot; human; fig 3
Zhu S, Chen Z, Katsha A, Hong J, Belkhiri A, el Rifai W. Regulation of CD44E by DARPP-32-dependent activation of SRp20 splicing factor in gastric tumorigenesis. Oncogene. 2016;35:1847-56 pubmed publisher
  • western blot; human; fig 6
Thieme R, Kurz S, Kolb M, Debebe T, Holtze S, Morhart M, et al. Analysis of Alpha-2 Macroglobulin from the Long-Lived and Cancer-Resistant Naked Mole-Rat and Human Plasma. PLoS ONE. 2015;10:e0130470 pubmed publisher
  • western blot; mouse
Wang W, Runkle K, Terkowski S, Ekaireb R, Witze E. Protein Depalmitoylation Is Induced by Wnt5a and Promotes Polarized Cell Behavior. J Biol Chem. 2015;290:15707-16 pubmed publisher
  • western blot; human; 1:1000; fig 2
Sharon C, Baranwal S, Patel N, Rodriguez Agudo D, Pandak W, Majumdar A, et al. Inhibition of insulin-like growth factor receptor/AKT/mammalian target of rapamycin axis targets colorectal cancer stem cells by attenuating mevalonate-isoprenoid pathway in vitro and in vivo. Oncotarget. 2015;6:15332-47 pubmed
  • immunohistochemistry - paraffin section; human; fig 8
  • western blot; human; fig 5
Kobayashi K, Sakurai K, Hiramatsu H, Inada K, Shiogama K, Nakamura S, et al. The miR-199a/Brm/EGR1 axis is a determinant of anchorage-independent growth in epithelial tumor cell lines. Sci Rep. 2015;5:8428 pubmed publisher
  • western blot; human; 1:2000; fig 3
Van Brocklyn J, Wojton J, Meisen W, Kellough D, Ecsedy J, Kaur B, et al. Aurora-A inhibition offers a novel therapy effective against intracranial glioblastoma. Cancer Res. 2014;74:5364-70 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100
Rito M, Schmitt F, Pinto A, André S. Fibromatosis-like metaplastic carcinoma of the breast has a claudin-low immunohistochemical phenotype. Virchows Arch. 2014;465:185-91 pubmed publisher
  • immunohistochemistry; human
  • western blot; human
Feng C, Zhang Y, Yin J, Li J, Abounader R, Zuo Z. Regulatory factor X1 is a new tumor suppressive transcription factor that acts via direct downregulation of CD44 in glioblastoma. Neuro Oncol. 2014;16:1078-85 pubmed publisher
Sikorska J, Gaweł D, Domek H, Rudzinska M, Czarnocka B. Podoplanin (PDPN) affects the invasiveness of thyroid carcinoma cells by inducing ezrin, radixin and moesin (E/R/M) phosphorylation in association with matrix metalloproteinases. BMC Cancer. 2019;19:85 pubmed publisher
Martin J, Julovi S, Lin M, de Silva H, Boyle F, Baxter R. Inhibition of basal-like breast cancer growth by FTY720 in combination with epidermal growth factor receptor kinase blockade. Breast Cancer Res. 2017;19:90 pubmed publisher
Rolland D, Basrur V, Jeon Y, McNeil Schwalm C, Fermin D, Conlon K, et al. Functional proteogenomics reveals biomarkers and therapeutic targets in lymphomas. Proc Natl Acad Sci U S A. 2017;114:6581-6586 pubmed publisher
Mittal K, Donthamsetty S, Kaur R, Yang C, Gupta M, Reid M, et al. Multinucleated polyploidy drives resistance to Docetaxel chemotherapy in prostate cancer. Br J Cancer. 2017;116:1186-1194 pubmed publisher
Nevi L, Carpino G, Costantini D, Cardinale V, Riccioni O, Di Matteo S, et al. Hyaluronan coating improves liver engraftment of transplanted human biliary tree stem/progenitor cells. Stem Cell Res Ther. 2017;8:68 pubmed publisher
Du L, LI Y, Fakih M, Wiatrek R, Duldulao M, Chen Z, et al. Role of SUMO activating enzyme in cancer stem cell maintenance and self-renewal. Nat Commun. 2016;7:12326 pubmed publisher
Yoon C, Chang K, Lee J, Tap W, Hart C, Simon M, et al. Multimodal targeting of tumor vasculature and cancer stem-like cells in sarcomas with VEGF-A inhibition, HIF-1? inhibition, and hypoxia-activated chemotherapy. Oncotarget. 2016;7:42844-42858 pubmed publisher
Ju H, Lu Y, Chen D, Tian T, Mo H, Wei X, et al. Redox Regulation of Stem-like Cells Though the CD44v-xCT Axis in Colorectal Cancer: Mechanisms and Therapeutic Implications. Theranostics. 2016;6:1160-75 pubmed publisher
Zhang H, Tao J, Sheng L, Hu X, Rong R, Xu M, et al. Twist2 promotes kidney cancer cell proliferation and invasion by regulating ITGA6 and CD44 expression in the ECM-receptor interaction pathway. Onco Targets Ther. 2016;9:1801-12 pubmed publisher
Zhang X, Guo W, Wang X, Liu X, Huang M, Gan L, et al. Antitumor activity and inhibitory effects on cancer stem cell-like properties of Adeno-associated virus (AAV) -mediated Bmi-1 interference driven by Bmi-1 promoter for gastric cancer. Oncotarget. 2016;7:22733-45 pubmed publisher
Zhang Q, Zhao W, Ye C, Zhuang J, Chang C, Li Y, et al. Honokiol inhibits bladder tumor growth by suppressing EZH2/miR-143 axis. Oncotarget. 2015;6:37335-48 pubmed publisher
Balasubramaniyan V, Vaillant B, Wang S, Gumin J, Butalid M, Sai K, et al. Aberrant mesenchymal differentiation of glioma stem-like cells: implications for therapeutic targeting. Oncotarget. 2015;6:31007-17 pubmed publisher
Cheng P, Phillips E, Kim S, Taylor D, Hielscher T, Puccio L, et al. Kinome-wide shRNA screen identifies the receptor tyrosine kinase AXL as a key regulator for mesenchymal glioblastoma stem-like cells. Stem Cell Reports. 2015;4:899-913 pubmed publisher
Kinose Y, Sawada K, Nakamura K, Sawada I, Toda A, Nakatsuka E, et al. The hypoxia-related microRNA miR-199a-3p displays tumor suppressor functions in ovarian carcinoma. Oncotarget. 2015;6:11342-56 pubmed
Dobbin Z, Katre A, Steg A, Erickson B, Shah M, Alvarez R, et al. Using heterogeneity of the patient-derived xenograft model to identify the chemoresistant population in ovarian cancer. Oncotarget. 2014;5:8750-64 pubmed
Kovacheva M, Zepp M, Berger S, Berger M. Sustained conditional knockdown reveals intracellular bone sialoprotein as essential for breast cancer skeletal metastasis. Oncotarget. 2014;5:5510-22 pubmed
Zhang Z, Dong Z, Lauxen I, Filho M, Nor J. Endothelial cell-secreted EGF induces epithelial to mesenchymal transition and endows head and neck cancer cells with stem-like phenotype. Cancer Res. 2014;74:2869-81 pubmed publisher
Nilubol N, Boufraqech M, Zhang L, Kebebew E. Loss of CPSF2 expression is associated with increased thyroid cancer cellular invasion and cancer stem cell population, and more aggressive disease. J Clin Endocrinol Metab. 2014;99:E1173-82 pubmed publisher
Zeng J, Ruan J, Luo L, Shi J, Cui Q, Yang J, et al. Molecular portraits of heterogeneity related to cancer stem cells in human ovarian cancer. Int J Gynecol Cancer. 2014;24:29-35 pubmed publisher
Nanashima A, Hatachi G, Tsuchiya T, Matsumoto H, Arai J, Abo T, et al. Clinical significances of cancer stem cells markers in patients with intrahepatic cholangiocarcinoma who underwent hepatectomy. Anticancer Res. 2013;33:2107-14 pubmed
Pervin S, Hewison M, Braga M, Tran L, Chun R, Karam A, et al. Down-regulation of vitamin D receptor in mammospheres: implications for vitamin D resistance in breast cancer and potential for combination therapy. PLoS ONE. 2013;8:e53287 pubmed publisher
Iida J, Dorchak J, Lehman J, Clancy R, Luo C, Chen Y, et al. FH535 inhibited migration and growth of breast cancer cells. PLoS ONE. 2012;7:e44418 pubmed publisher
Vieira A, Ricardo S, Ablett M, Dionísio M, Mendes N, Albergaria A, et al. P-cadherin is coexpressed with CD44 and CD49f and mediates stem cell properties in basal-like breast cancer. Stem Cells. 2012;30:854-64 pubmed publisher
Zaytseva Y, Rychahou P, Gulhati P, Elliott V, Mustain W, O CONNOR K, et al. Inhibition of fatty acid synthase attenuates CD44-associated signaling and reduces metastasis in colorectal cancer. Cancer Res. 2012;72:1504-17 pubmed publisher
Gilbert C, Parwani A. The use of multispectral imaging to distinguish reactive urothelium from neoplastic urothelium. J Pathol Inform. 2010;1:23 pubmed publisher
Golubkov V, Chekanov A, Cieplak P, Aleshin A, Chernov A, Zhu W, et al. The Wnt/planar cell polarity protein-tyrosine kinase-7 (PTK7) is a highly efficient proteolytic target of membrane type-1 matrix metalloproteinase: implications in cancer and embryogenesis. J Biol Chem. 2010;285:35740-9 pubmed publisher
product information
SKU :
3570S
Product-Name :
CD44 (156-3C11) Mouse mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H
Applications :
Flow cytometry
Product-Category :
Immunology and Inflammation
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
80
Host :
Mouse
Target :
CD44
Primary-Protein :
CD44
Alt-Names :
CD44,CD44 antigen,CD44 antigen (homing function and Indian blood group system),CD44 molecule (Indian blood group),CDW44 antigen,CDw44,CSPG8,ECMR-III,Epican,Extracellular matrix receptor III,GP90 lymphocyte homing/adhesion receptor,HCELL,HUTCH-I,Heparan sulfate proteoglycan,Hermes antigen,Hyaluronate receptor,IN,LHR,MC56,MDU2,MDU3,MGC10468,MIC4,MUTCH-I,PGP-1,PGP-I,Pgp1,Phagocytic glycoprotein 1,Phagocytic glycoprotein I,antigen gp90 homing receptor,cell adhesion molecule,cell surface glycoprotein CD44,chondroitin sulfate proteoglycan 8,extracellular matrix receptor-III,hematopoietic cell E- and L-selectin ligand,homing function and Indian blood group system
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.