product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
NPM Antibody
catalog :
3542
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
citations: 11
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 5
Catanzaro G, Besharat Z, Garg N, Ronci M, Pieroni L, Miele E, et al. MicroRNAs-Proteomic Networks Characterizing Human Medulloblastoma-SLCs. Stem Cells Int. 2016;2016:2683042 pubmed publisher
  • western blot; mouse; 1:1000; fig 5
Sun Y, Fu A, Xu W, Chao J, Moshiach S, Morris S. Myeloid leukemia factor 1 interfered with Bcl-XL to promote apoptosis and its function was regulated by 14-3-3. J Physiol Biochem. 2015;71:807-21 pubmed publisher
Doran A, Ozcan L, Cai B, Zheng Z, Fredman G, Rymond C, et al. CAMKII? suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosis. J Clin Invest. 2017;127:4075-4089 pubmed publisher
Ando K, PARSONS M, Shah R, Charendoff C, Paris S, Liu P, et al. NPM1 directs PIDDosome-dependent caspase-2 activation in the nucleolus. J Cell Biol. 2017;216:1795-1810 pubmed publisher
Modelska A, Turro E, Russell R, Beaton J, Sbarrato T, Spriggs K, et al. The malignant phenotype in breast cancer is driven by eIF4A1-mediated changes in the translational landscape. Cell Death Dis. 2015;6:e1603 pubmed publisher
Kodiha M, Salimi A, Wang Y, Stochaj U. Pharmacological AMP kinase activators target the nucleolar organization and control cell proliferation. PLoS ONE. 2014;9:e88087 pubmed publisher
Chiarella S, De Cola A, Scaglione G, Carletti E, Graziano V, Barcaroli D, et al. Nucleophosmin mutations alter its nucleolar localization by impairing G-quadruplex binding at ribosomal DNA. Nucleic Acids Res. 2013;41:3228-39 pubmed publisher
Chou S, Ko B, Chiou J, Hsu Y, Tsai M, Chiu Y, et al. A knock-in Npm1 mutation in mice results in myeloproliferation and implies a perturbation in hematopoietic microenvironment. PLoS ONE. 2012;7:e49769 pubmed publisher
Bier C, Hecht R, Kunst L, Scheiding S, Wünsch D, Goesswein D, et al. Overexpression of the catalytically impaired Taspase1 T234V or Taspase1 D233A variants does not have a dominant negative effect in T(4;11) leukemia cells. PLoS ONE. 2012;7:e34142 pubmed publisher
Guery L, Benikhlef N, Gautier T, Paul C, Jego G, Dufour E, et al. Fine-tuning nucleophosmin in macrophage differentiation and activation. Blood. 2011;118:4694-704 pubmed publisher
Kodiha M, Bański P, Stochaj U. Computer-based fluorescence quantification: a novel approach to study nucleolar biology. BMC Cell Biol. 2011;12:25 pubmed publisher
product information
SKU :
3542S
Product-Name :
NPM Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R
Applications :
Immunohistochemistry (Paraffin)
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
38
Host :
Rabbit
Target :
NPM1
Primary-Protein :
NPM1
Alt-Names :
B23,MGC104254,NPM,NPM1,Nucleolar phosphoprotein B23,Nucleolar protein NO38,Nucleophosmin,Numatrin,nucleophosmin (nucleolar phosphoprotein B23, numatrin),nucleophosmin/nucleoplasmin family, member 1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.