product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-NPM (Thr199) Antibody
catalog :
3541S
quantity :
100 ul
price :
274 USD
clonality :
polyclonal
host :
rabbit
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 6
Published Application/Species/DilutionReference
  • western blot; human; fig 3
Trapé A, Liu S, Cortés A, Ueno N, Gonzalez-Angulo A. Effects of CDK4/6 Inhibition in Hormone Receptor-Positive/Human Epidermal Growth Factor Receptor 2-Negative Breast Cancer Cells with Acquired Resistance to Paclitaxel. J Cancer. 2016;7:947-56 pubmed publisher
  • western blot; human
Lee M, Moreno C, Saavedra H. E2F activators signal and maintain centrosome amplification in breast cancer cells. Mol Cell Biol. 2014;34:2581-99 pubmed
  • western blot; mouse; fig s3
Pekkonen P, Järviluoma A, Zinovkina N, Cvrljevic A, Prakash S, Westermarck J, et al. KSHV viral cyclin interferes with T-cell development and induces lymphoma through Cdk6 and Notch activation in vivo. Cell Cycle. 2014;13:3670-84 pubmed publisher
  • western blot; human
Harrison Pitner M, Saavedra H. Cdk4 and nek2 signal binucleation and centrosome amplification in a her2+ breast cancer model. PLoS ONE. 2013;8:e65971 pubmed publisher
Lin C, Tan B, Liu H, Shih C, Chien K, Lin C, et al. Dephosphorylation of nucleophosmin by PP1β facilitates pRB binding and consequent E2F1-dependent DNA repair. Mol Biol Cell. 2010;21:4409-17 pubmed publisher
So C, Michal A, Mashayekhi R, Benovic J. G protein-coupled receptor kinase 5 phosphorylates nucleophosmin and regulates cell sensitivity to polo-like kinase 1 inhibition. J Biol Chem. 2012;287:17088-99 pubmed publisher
product information
SKU :
3541S
Product-Name :
Phospho-NPM (Thr199) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
38
Host :
Rabbit
Target :
NPM1 (Thr199) phosphate
Primary-Protein :
NPM1
Alt-Names :
B23,MGC104254,NPM,NPM1,Nucleolar phosphoprotein B23,Nucleolar protein NO38,Nucleophosmin,Numatrin,nucleophosmin (nucleolar phosphoprotein B23, numatrin),nucleophosmin/nucleoplasmin family, member 1
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.