product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
GLI1 (C68H3) Rabbit mAb
catalog :
3538S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human
application :
western blot, immunohistochemistry, immunoprecipitation
citations: 6
Published Application/Species/DilutionReference
  • western blot; human; 1:1000; fig 6
Wang H, Ning Z, Li Y, Zhu X, Meng Z. Bufalin suppresses cancer stem-like cells in gemcitabine-resistant pancreatic cancer cells via Hedgehog signaling. Mol Med Rep. 2016;14:1907-14 pubmed publisher
  • immunohistochemistry; human; 1:200
  • western blot; human
Sun Y, Guo W, Ren T, Liang W, Zhou W, Lu Q, et al. Gli1 inhibition suppressed cell growth and cell cycle progression and induced apoptosis as well as autophagy depending on ERK1/2 activity in human chondrosarcoma cells. Cell Death Dis. 2014;5:e979 pubmed publisher
  • western blot; human
So J, Lin J, Wahler J, Liby K, Sporn M, Suh N. A synthetic triterpenoid CDDO-Im inhibits tumorsphere formation by regulating stem cell signaling pathways in triple-negative breast cancer. PLoS ONE. 2014;9:e107616 pubmed publisher
Larsen A, Bai R, Chung J, Borodovsky A, Rudin C, Riggins G, et al. Repurposing the antihelmintic mebendazole as a hedgehog inhibitor. Mol Cancer Ther. 2015;14:3-13 pubmed publisher
Fan C, Wang Y, Liu Z, Sun Y, Wang X, Wei G, et al. Metformin exerts anticancer effects through the inhibition of the Sonic hedgehog signaling pathway in breast cancer. Int J Mol Med. 2015;36:204-14 pubmed publisher
Hou X, Chen X, Zhang P, Fan Y, Ma A, Pang T, et al. Inhibition of hedgehog signaling by GANT58 induces apoptosis and shows synergistic antitumor activity with AKT inhibitor in acute T cell leukemia cells. Biochimie. 2014;101:50-9 pubmed publisher
product information
SKU :
3538S
Product-Name :
GLI1 (C68H3) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H
Applications :
Immunoprecipitation
Product-Category :
Developmental Biology
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
160
Host :
Rabbit
Target :
GLI1
Primary-Protein :
GLI1
Alt-Names :
GLI,GLI family zinc finger 1,GLI1,Glioma-associated oncogene,Oncogene GLI,Zinc finger protein GLI1,glioma-associated oncogene family zinc finger 1,glioma-associated oncogene homolog 1 (zinc finger protein)
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.