GLI1 (C68H3) Rabbit mAb | Cell Signaling Technology 3538 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

GLI1 (C68H3) Rabbit mAb

catalog :

3538

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

C68H3

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Cell Signaling Technology product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; loading ...; fig 3b western blot; mouse; loading ...; fig 2a	Lu J, Liu L, Zheng M, Li X, Wu A, Wu Q, et al. MEKK2 and MEKK3 suppress Hedgehog pathway-dependent medulloblastoma by inhibiting GLI1 function. Oncogene. 2018;37:3864-3878 pubmed publisher
western blot; human; loading ...; fig 5	Galoian K, Luo S, Qureshi A, Patel P, Price R, Morse A, et al. Effect of cytostatic proline rich polypeptide-1 on tumor suppressors of inflammation pathway signaling in chondrosarcoma. Mol Clin Oncol. 2016;5:618-624 pubmed
western blot; human; 1:1000; fig 6	Wang H, Ning Z, Li Y, Zhu X, Meng Z. Bufalin suppresses cancer stem-like cells in gemcitabine-resistant pancreatic cancer cells via Hedgehog signaling. Mol Med Rep. 2016;14:1907-14 pubmed publisher
immunohistochemistry - paraffin section; human; 1:100; fig 4 western blot; human; 1:1000; fig 1	Fan C, Wang Y, Liu Z, Sun Y, Wang X, Wei G, et al. Metformin exerts anticancer effects through the inhibition of the Sonic hedgehog signaling pathway in breast cancer. Int J Mol Med. 2015;36:204-14 pubmed publisher
western blot; human	So J, Lin J, Wahler J, Liby K, Sporn M, Suh N. A synthetic triterpenoid CDDO-Im inhibits tumorsphere formation by regulating stem cell signaling pathways in triple-negative breast cancer. PLoS ONE. 2014;9:e107616 pubmed publisher
western blot; human; loading ...; fig 8a	Zahreddine H, Culjkovic Kraljacic B, Assouline S, Gendron P, Romeo A, Morris S, et al. The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation. Nature. 2014;511:90-3 pubmed publisher
immunohistochemistry; human; 1:200 western blot; human	Sun Y, Guo W, Ren T, Liang W, Zhou W, Lu Q, et al. Gli1 inhibition suppressed cell growth and cell cycle progression and induced apoptosis as well as autophagy depending on ERK1/2 activity in human chondrosarcoma cells. Cell Death Dis. 2014;5:e979 pubmed publisher
	Chahal K, Li J, Kufareva I, Parle M, Durden D, Wechsler Reya R, et al. Nilotinib, an approved leukemia drug, inhibits smoothened signaling in Hedgehog-dependent medulloblastoma. PLoS ONE. 2019;14:e0214901 pubmed publisher
	Ooki A, Dinalankara W, Marchionni L, Tsay J, Goparaju C, Maleki Z, et al. Epigenetically regulated PAX6 drives cancer cells toward a stem-like state via GLI-SOX2 signaling axis in lung adenocarcinoma. Oncogene. 2018;37:5967-5981 pubmed publisher
	Larsen A, Bai R, Chung J, Borodovsky A, Rudin C, Riggins G, et al. Repurposing the antihelmintic mebendazole as a hedgehog inhibitor. Mol Cancer Ther. 2015;14:3-13 pubmed publisher
	Hou X, Chen X, Zhang P, Fan Y, Ma A, Pang T, et al. Inhibition of hedgehog signaling by GANT58 induces apoptosis and shows synergistic antitumor activity with AKT inhibitor in acute T cell leukemia cells. Biochimie. 2014;101:50-9 pubmed publisher

product information

SKU :

3538S

Product-Name :

GLI1 (C68H3) Rabbit mAb

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

Applications :

Immunoprecipitation

Product-Category :

Developmental Biology

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

160

Host :

Rabbit

Target :

GLI1

Primary-Protein :

GLI1

Alt-Names :

GLI,GLI family zinc finger 1,GLI1,Glioma-associated oncogene,Oncogene GLI,Zinc finger protein GLI1,glioma-associated oncogene family zinc finger 1,glioma-associated oncogene homolog 1 (zinc finger protein)

more info or order :

Cell Signaling Technology product webpage