product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
CD31 (PECAM-1) (89C2) Mouse mAb
catalog :
3528
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
89C2
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 25
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 4
Luo L, Chen L, Ke K, Zhao B, Wang L, Zhang C, et al. High expression levels of CLEC4M indicate poor prognosis in patients with hepatocellular carcinoma. Oncol Lett. 2020;19:1711-1720 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 3f
Li H, Liao Y, Gao L, Zhuang T, Huang Z, Zhu H, et al. Coronary Serum Exosomes Derived from Patients with Myocardial Ischemia Regulate Angiogenesis through the miR-939-mediated Nitric Oxide Signaling Pathway. Theranostics. 2018;8:2079-2093 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:100; loading ...; fig 3b
Wang D, Ding X, Xue W, Zheng J, Tian X, Li Y, et al. A new scaffold containing small intestinal submucosa and mesenchymal stem cells improves pancreatic islet function and survival in vitro and in vivo. Int J Mol Med. 2017;39:167-173 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...
Dallavalle C, Albino D, Civenni G, Merulla J, Ostano P, Mello Grand M, et al. MicroRNA-424 impairs ubiquitination to activate STAT3 and promote prostate tumor progression. J Clin Invest. 2016;126:4585-4602 pubmed publisher
  • immunocytochemistry; human; 1:1000; tbl 2
Kilic O, Pamies D, Lavell E, Schiapparelli P, Feng Y, Hartung T, et al. Brain-on-a-chip model enables analysis of human neuronal differentiation and chemotaxis. Lab Chip. 2016;16:4152-4162 pubmed
  • western blot; mouse; loading ...; fig 4b
  • immunohistochemistry; human; loading ...; fig 1e
  • western blot; human; loading ...; fig 2h
Matkar P, Singh K, Rudenko D, Kim Y, Kuliszewski M, Prud homme G, et al. Novel regulatory role of neuropilin-1 in endothelial-to-mesenchymal transition and fibrosis in pancreatic ductal adenocarcinoma. Oncotarget. 2016;7:69489-69506 pubmed publisher
  • western blot; human; loading ...; fig 2b
Kotlarczyk M, Billaud M, Green B, Hill J, Shiva S, Kelley E, et al. Regional Disruptions in Endothelial Nitric Oxide Pathway Associated With Bicuspid Aortic Valve. Ann Thorac Surg. 2016;102:1274-81 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100
Di Marco M, Grassi E, Vecchiarelli S, Durante S, Macchini M, Biasco G. Retroperitoneal lymphangioma: A report of 2 cases and a review of the literature regarding the differential diagnoses of retroperitoneal cystic masses. Oncol Lett. 2016;11:3161-3166 pubmed
  • immunohistochemistry - paraffin section; human; 1:1000; fig 4
Zhou Z, Tang A, Wong W, Bamezai S, Goddard L, Shenkar R, et al. Cerebral cavernous malformations arise from endothelial gain of MEKK3-KLF2/4 signalling. Nature. 2016;532:122-6 pubmed publisher
  • western blot; human; 1:1000; fig s6
Heemskerk N, Schimmel L, Oort C, van Rijssel J, Yin T, Ma B, et al. F-actin-rich contractile endothelial pores prevent vascular leakage during leukocyte diapedesis through local RhoA signalling. Nat Commun. 2016;7:10493 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 4
Guye P, Ebrahimkhani M, Kipniss N, Velazquez J, Schoenfeld E, Kiani S, et al. Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6. Nat Commun. 2016;7:10243 pubmed publisher
  • western blot; human; fig 6
Prasad S, Sajja R, Park J, Naik P, Kaisar M, Cucullo L. Impact of cigarette smoke extract and hyperglycemic conditions on blood-brain barrier endothelial cells. Fluids Barriers CNS. 2015;12:18 pubmed publisher
  • western blot; human
Singh K, Lovren F, Pan Y, Quan A, Ramadan A, Matkar P, et al. The essential autophagy gene ATG7 modulates organ fibrosis via regulation of endothelial-to-mesenchymal transition. J Biol Chem. 2015;290:2547-59 pubmed publisher
  • western blot; human
Model L, Hall M, Wong D, Muto A, Kondo Y, Ziegler K, et al. Arterial shear stress reduces eph-b4 expression in adult human veins. Yale J Biol Med. 2014;87:359-71 pubmed
  • immunohistochemistry - paraffin section; human; 1:100
Dowie M, Grimsey N, Hoffman T, Faull R, Glass M. Cannabinoid receptor CB2 is expressed on vascular cells, but not astroglial cells in the post-mortem human Huntington's disease brain. J Chem Neuroanat. 2014;59-60:62-71 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200
Jeon H, Kim S, Jin X, Park J, Kim S, Joshi K, et al. Crosstalk between glioma-initiating cells and endothelial cells drives tumor progression. Cancer Res. 2014;74:4482-92 pubmed publisher
  • immunocytochemistry; human
Pryzhkova M, Aria I, Cheng Q, Harris G, Zan X, Gharib M, et al. Carbon nanotube-based substrates for modulation of human pluripotent stem cell fate. Biomaterials. 2014;35:5098-109 pubmed publisher
  • immunocytochemistry; human
  • western blot; human
Byron A, Randles M, Humphries J, Mironov A, Hamidi H, Harris S, et al. Glomerular cell cross-talk influences composition and assembly of extracellular matrix. J Am Soc Nephrol. 2014;25:953-66 pubmed publisher
Umezawa Y, Akiyama H, Okada K, Ishida S, Nogami A, Oshikawa G, et al. Molecular mechanisms for enhancement of stromal cell-derived factor 1-induced chemotaxis by platelet endothelial cell adhesion molecule 1 (PECAM-1). J Biol Chem. 2017;292:19639-19655 pubmed publisher
Ye X, Abou Rayyah Y, Bischoff J, Ritchie A, Sebire N, Watts P, et al. Altered ratios of pro- and anti-angiogenic VEGF-A variants and pericyte expression of DLL4 disrupt vascular maturation in infantile haemangioma. J Pathol. 2016;239:139-51 pubmed publisher
Naik P, Fofaria N, Prasad S, Sajja R, Weksler B, Couraud P, et al. Oxidative and pro-inflammatory impact of regular and denicotinized cigarettes on blood brain barrier endothelial cells: is smoking reduced or nicotine-free products really safe?. BMC Neurosci. 2014;15:51 pubmed publisher
Hsu C, Hsieh T, Tsai C, Tsai H, Chen H, Chang Y, et al. miRNA-199a-5p regulates VEGFA in endometrial mesenchymal stem cells and contributes to the pathogenesis of endometriosis. J Pathol. 2014;232:330-43 pubmed publisher
Angelucci C, Maulucci G, Lama G, Proietti G, Colabianchi A, Papi M, et al. Epithelial-stromal interactions in human breast cancer: effects on adhesion, plasma membrane fluidity and migration speed and directness. PLoS ONE. 2012;7:e50804 pubmed publisher
Iacopino F, Angelucci C, Sica G. Interactions between normal human fibroblasts and human prostate cancer cells in a co-culture system. Anticancer Res. 2012;32:1579-88 pubmed
Whyte J, Ball S, Shuttleworth C, Brennan K, Kielty C. Density of human bone marrow stromal cells regulates commitment to vascular lineages. Stem Cell Res. 2011;6:238-50 pubmed publisher
product information
SKU :
3528S
Product-Name :
CD31 (PECAM-1) (89C2) Mouse mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H
Applications :
Flow cytometry
Product-Category :
Immunology and Inflammation
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
130
Host :
Mouse
Target :
PECAM-1
Primary-Protein :
PECAM-1
Alt-Names :
CD31,CD31 antigen,CD31/EndoCAM,EndoCAM,FLJ58394,GPIIA ,PECA1,PECAM-1,PECAM-1, CD31/EndoCAM,PECAM1,Platelet endothelial cell adhesion molecule,adhesion molecule,platelet/endothelial cell adhesion molecule
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.