product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-MDM2 (Ser166) Antibody
catalog :
3521S
quantity :
100 ul
price :
274 USD
clonality :
polyclonal
host :
rabbit
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
western blot, other
more info or order :
Cell Signaling Technology product webpage
citations: 7
Published Application/Species/DilutionReference
  • western blot; human; fig 4e
Chavoshi S, Egorova O, Lacdao I, Farhadi S, Sheng Y, Saridakis V. Identification of Kaposi Sarcoma Herpesvirus (KSHV) vIRF1 Protein as a Novel Interaction Partner of Human Deubiquitinase USP7. J Biol Chem. 2016;291:6281-91 pubmed publisher
  • other; mouse; 1:1000; fig s1
Chiang C, Uzoma I, Lane D, Memisevic V, Alem F, Yao K, et al. A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection. Front Microbiol. 2015;6:683 pubmed publisher
  • western blot; human
Giovannini C, Minguzzi M, Baglioni M, Fornari F, Giannone F, Ravaioli M, et al. Suppression of p53 by Notch3 is mediated by Cyclin G1 and sustained by MDM2 and miR-221 axis in hepatocellular carcinoma. Oncotarget. 2014;5:10607-20 pubmed
  • western blot; human
Lau R, Niu M, Pratt M. cIAP2 represses IKKα/β-mediated activation of MDM2 to prevent p53 degradation. Cell Cycle. 2012;11:4009-19 pubmed publisher
  • western blot; human
Hirata H, Hinoda Y, Nakajima K, Kawamoto K, Kikuno N, Ueno K, et al. Wnt antagonist DKK1 acts as a tumor suppressor gene that induces apoptosis and inhibits proliferation in human renal cell carcinoma. Int J Cancer. 2011;128:1793-803 pubmed publisher
Tin A, Park A, Sundar S, Firestone G. Essential role of the cancer stem/progenitor cell marker nucleostemin for indole-3-carbinol anti-proliferative responsiveness in human breast cancer cells. BMC Biol. 2014;12:72 pubmed publisher
Gonzalez E, Rother M, Kerr M, Al-Zeer M, Abu-Lubad M, Kessler M, et al. Chlamydia infection depends on a functional MDM2-p53 axis. Nat Commun. 2014;5:5201 pubmed publisher
product information
SKU :
3521S
Product-Name :
Phospho-MDM2 (Ser166) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R
Applications :
Western blot
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
90
Host :
Rabbit
Target :
MDM2 (Ser166) phosphate
Primary-Protein :
MDM2
Alt-Names :
Double minute 2 protein,E3 ubiquitin-protein ligase Mdm2,HDMX,Hdm2,MDM2,MGC5370,MGC71221,Mdm2 p53 binding protein homolog (mouse),Mdm2, transformed 3T3 cell double minute 2, p53 binding protein,Oncoprotein Mdm2,double minute 2, human homolog of,p53-binding protein,p53-binding protein Mdm2,ubiquitin-protein ligase E3 Mdm2
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.