product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
MLH1 (4C9C7) Mouse mAb
catalog :
3515
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4C9C7
reactivity :
human
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry
more info or order :
Cell Signaling Technology product webpage
citations: 6
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig e10b
Chan E, Shibue T, McFarland J, Gaeta B, Ghandi M, Dumont N, et al. WRN helicase is a synthetic lethal target in microsatellite unstable cancers. Nature. 2019;568:551-556 pubmed publisher
  • western blot; human; 1:1000; loading ...
Lieb S, Blaha Ostermann S, Kamper E, Rippka J, Schwarz C, Ehrenhöfer Wölfer K, et al. Werner syndrome helicase is a selective vulnerability of microsatellite instability-high tumor cells. elife. 2019;8: pubmed publisher
  • western blot; human; loading ...; fig s1e
Takahashi Y, Wu J, Suzuki K, Martínez Redondo P, Li M, Liao H, et al. Integration of CpG-free DNA induces de novo methylation of CpG islands in pluripotent stem cells. Science. 2017;356:503-508 pubmed publisher
  • western blot; human; 1:1000; fig 1g
Masuda Y, Takahashi H, Sato S, Tomomori Sato C, Saraf A, Washburn M, et al. TRIM29 regulates the assembly of DNA repair proteins into damaged chromatin. Nat Commun. 2015;6:7299 pubmed publisher
  • western blot; human; fig s4
Ramirez Y, Mladek A, Phillips R, Gynther M, Rautio J, Ross A, et al. Evaluation of novel imidazotetrazine analogues designed to overcome temozolomide resistance and glioblastoma regrowth. Mol Cancer Ther. 2015;14:111-9 pubmed publisher
  • western blot; human
Chen J, Miller B, Furano A. Repair of naturally occurring mismatches can induce mutations in flanking DNA. elife. 2014;3:e02001 pubmed publisher
product information
SKU :
3515S
Product-Name :
MLH1 (4C9C7) Mouse mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, Mk
Applications :
Flow cytometry
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
85
Host :
Mouse
Target :
MLH1
Primary-Protein :
MLH1
Alt-Names :
COCA2,DNA mismatch repair protein Mlh1,FCC2,HNPCC,HNPCC2,MGC5172,MLH1,MutL protein homolog 1,hMLH1,mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.