| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot knockout validation; human; 1:1000; loading ...; fig 5b
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- western blot; human; 1:1000; loading ...; fig 4c
| Li R, Hao Y, Wang Q, Meng Y, Wu K, Liu C, et al. ECHS1, an interacting protein of LASP1, induces sphingolipid-metabolism imbalance to promote colorectal cancer progression by regulating ceramide glycosylation. Cell Death Dis. 2021;12:911 pubmed publisher |
- western blot; mouse; loading ...; fig 4a
| Cao Y, Li Q, Yang Y, Ke Z, Chen S, Li M, et al. Cardioprotective Effect of Stem-Leaf Saponins From Panax notoginseng on Mice With Sleep Derivation by Inhibiting Abnormal Autophagy Through PI3K/Akt/mTOR Pathway. Front Cardiovasc Med. 2021;8:694219 pubmed publisher |
- western blot; mouse; loading ...; fig 4a
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- western blot; human; 1:1000; loading ...; fig 7h
| Li H, Zhao S, Shen L, Wang P, Liu S, Ma Y, et al. E2F2 inhibition induces autophagy via the PI3K/Akt/mTOR pathway in gastric cancer. Aging (Albany NY). 2021;13:13626-13643 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 7c
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- western blot; human; 1:1000; loading ...; fig 4g
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- western blot; human; fig 6b
| Zhang L, He J, Wang J, Liu J, Chen Z, Deng B, et al. Knockout RAGE alleviates cardiac fibrosis through repressing endothelial-to-mesenchymal transition (EndMT) mediated by autophagy. Cell Death Dis. 2021;12:470 pubmed publisher |
- western blot; human; loading ...; fig 1a
| Liu Y, Xu S, Zhang H, Qian K, Huang J, Gu X, et al. Stimulation of α7-nAChRs coordinates autophagy and apoptosis signaling in experimental knee osteoarthritis. Cell Death Dis. 2021;12:448 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 5a
| Zhou H, Li G, Wang Y, Jiang R, Li Y, Wang H, et al. Microbial Metabolite Sodium Butyrate Attenuates Cartilage Degradation by Restoring Impaired Autophagy and Autophagic Flux in Osteoarthritis Development. Front Pharmacol. 2021;12:659597 pubmed publisher |
- western blot; human; fig 4b
| Chen Y, Wang R, Huang S, Henson E, Bi J, Gibson S. Erb-b2 Receptor Tyrosine Kinase 2 (ERBB2) Promotes ATG12-Dependent Autophagy Contributing to Treatment Resistance of Breast Cancer Cells. Cancers (Basel). 2021;13: pubmed publisher |
- western blot; mouse; loading ...; fig 2a
| Wang C, Chen C, Lin M, Su H, Ho M, Yeh J, et al. TLR9 Binding to Beclin 1 and Mitochondrial SIRT3 by a Sodium-Glucose Co-Transporter 2 Inhibitor Protects the Heart from Doxorubicin Toxicity. Biology (Basel). 2020;9: pubmed publisher |
- western blot; rat; 1:1000; loading ...; fig 3a
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- western blot; mouse; 1:1000; loading ...; fig 3a
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- western blot; rat; loading ...; fig 3a
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- western blot; human; loading ...; fig 5c
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- western blot; human; loading ...; fig 4c
- western blot; mouse; loading ...; fig 4d, s4d
| Losier T, Akuma M, McKee Muir O, LeBlond N, Suk Y, Alsaadi R, et al. AMPK Promotes Xenophagy through Priming of Autophagic Kinases upon Detection of Bacterial Outer Membrane Vesicles. Cell Rep. 2019;26:2150-2165.e5 pubmed publisher |
- western blot; human; loading ...; fig 5b
| Mukhopadhyay U, Chanda S, Patra U, Mukherjee A, Rana S, Mukherjee A, et al. Synchronized Orchestration of miR-99b and let-7g Positively Regulates Rotavirus Infection by Modulating Autophagy. Sci Rep. 2019;9:1318 pubmed publisher |
- western blot; mouse; loading ...; fig 5e
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- western blot; mouse; 1:1000; loading ...; fig 6d
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- western blot; human; fig 5d
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- western blot; mouse; 1:1000; loading ...; fig 5d
- western blot; human; 1:1000; loading ...; fig 5c
| Xu Y, Wang Y, Yao A, Xu Z, Dou H, Shen S, et al. Low Frequency Magnetic Fields Induce Autophagy-associated Cell Death in Lung Cancer through miR-486-mediated Inhibition of Akt/mTOR Signaling Pathway. Sci Rep. 2017;7:11776 pubmed publisher |
- western blot; rat; loading ...; fig 2h
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- western blot; mouse; 1:1000; loading ...; fig 8c
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- western blot; mouse; fig s2b
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- western blot; human; loading ...; fig 5c
| Xu Q, Zhu N, Chen S, Zhao P, Ren H, Zhu S, et al. E3 Ubiquitin Ligase Nedd4 Promotes Japanese Encephalitis Virus Replication by Suppressing Autophagy in Human Neuroblastoma Cells. Sci Rep. 2017;7:45375 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 1e
| Mu Y, Yan W, Yin T, Zhang Y, Li J, Yang J. Diet-induced obesity impairs spermatogenesis: a potential role for autophagy. Sci Rep. 2017;7:43475 pubmed publisher |
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- western blot; human; 1:1000; loading ...; fig s4a
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- western blot; mouse; loading ...; fig 2a
| Li J, Chen T, Xiao M, Li N, Wang S, Su H, et al. Mouse Sirt3 promotes autophagy in AngII-induced myocardial hypertrophy through the deacetylation of FoxO1. Oncotarget. 2016;7:86648-86659 pubmed publisher |
- western blot; mouse; loading ...; fig 2e
| Qin Y, Liu Y, Hao W, Decker Y, Tomic I, Menger M, et al. Stimulation of TLR4 Attenuates Alzheimer's Disease-Related Symptoms and Pathology in Tau-Transgenic Mice. J Immunol. 2016;197:3281-3292 pubmed |
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| Bartlett J, Trivedi P, Yeung P, Kienesberger P, Pulinilkunnil T. Doxorubicin impairs cardiomyocyte viability by suppressing transcription factor EB expression and disrupting autophagy. Biochem J. 2016;473:3769-3789 pubmed |
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- western blot; human; 1:1000; loading ...; fig 1d
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- western blot; mouse; 1:1000; fig S8
| Basisty N, Dai D, Gagnidze A, Gitari L, Fredrickson J, Maina Y, et al. Mitochondrial-targeted catalase is good for the old mouse proteome, but not for the young: 'reverse' antagonistic pleiotropy?. Aging Cell. 2016;15:634-45 pubmed publisher |
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- western blot; mouse; 1:1000; tbl 1
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- immunoprecipitation; human; fig 5
- western blot; human; fig 5
| Lei Y, Kansy B, Li J, Cong L, Liu Y, Trivedi S, et al. EGFR-targeted mAb therapy modulates autophagy in head and neck squamous cell carcinoma through NLRX1-TUFM protein complex. Oncogene. 2016;35:4698-707 pubmed publisher |
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| Selleck E, Orchard R, Lassen K, Beatty W, Xavier R, Levine B, et al. A Noncanonical Autophagy Pathway Restricts Toxoplasma gondii Growth in a Strain-Specific Manner in IFN-γ-Activated Human Cells. MBio. 2015;6:e01157-15 pubmed publisher |
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| Moreau K, Ghislat G, Hochfeld W, Renna M, Zavodszky E, Runwal G, et al. Transcriptional regulation of Annexin A2 promotes starvation-induced autophagy. Nat Commun. 2015;6:8045 pubmed publisher |
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- immunoprecipitation; human; fig s2a
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| Lee S, Kim M, Lim W, Kim T, Kang C. Strenuous exercise induces mitochondrial damage in skeletal muscle of old mice. Biochem Biophys Res Commun. 2015;461:354-60 pubmed publisher |
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- western blot; rat
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- immunoprecipitation; human; 2 ug/time
- immunocytochemistry; human
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| Kim T, Kim H, Kang Y, Yoon S, Lee J, Choi W, et al. Psammaplin A induces Sirtuin 1-dependent autophagic cell death in doxorubicin-resistant MCF-7/adr human breast cancer cells and xenografts. Biochim Biophys Acta. 2015;1850:401-10 pubmed publisher |
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- western blot; human; 1:1000; fig 1a
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| Liu X, Yao J, Tripathi D, Ding Z, Xu Y, Sun M, et al. Autophagy mediates HIF2α degradation and suppresses renal tumorigenesis. Oncogene. 2015;34:2450-60 pubmed publisher |
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| Porter K, Jeyabalan N, Liton P. MTOR-independent induction of autophagy in trabecular meshwork cells subjected to biaxial stretch. Biochim Biophys Acta. 2014;1843:1054-62 pubmed publisher |
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| Zhong L, Shu W, Dai W, Gao B, Xiong S. Reactive Oxygen Species-Mediated c-Jun NH2-Terminal Kinase Activation Contributes to Hepatitis B Virus X Protein-Induced Autophagy via Regulation of the Beclin-1/Bcl-2 Interaction. J Virol. 2017;91: pubmed publisher |
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| Zhang C, Jiang Y, Zhang J, Huang J, Wang J. 8-p-Hdroxybenzoyl Tovarol Induces Paraptosis Like Cell Death and Protective Autophagy in Human Cervical Cancer HeLa Cells. Int J Mol Sci. 2015;16:14979-96 pubmed publisher |
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| Ye L, Yu J, Liang Y, Zeng J, Huang R, Liao S. Beclin 1 knockdown retards re-endothelialization and exacerbates neointimal formation via a crosstalk between autophagy and apoptosis. Atherosclerosis. 2014;237:146-54 pubmed publisher |
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| Porter K, Nallathambi J, Lin Y, Liton P. Lysosomal basification and decreased autophagic flux in oxidatively stressed trabecular meshwork cells: implications for glaucoma pathogenesis. Autophagy. 2013;9:581-94 pubmed publisher |
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