product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Pyk2 (5E2) Mouse mAb
catalog :
3480S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
mouse
clone name :
5E2
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 6
Published Application/Species/DilutionReference
  • western blot (knockdown validation); human; fig 6c
Wu X, Zahari M, Renuse S, Nirujogi R, Kim M, Manda S, et al. Phosphoproteomic Analysis Identifies Focal Adhesion Kinase 2 (FAK2) as a Potential Therapeutic Target for Tamoxifen Resistance in Breast Cancer. Mol Cell Proteomics. 2015;14:2887-900 pubmed publisher
  • western blot (knockdown validation); mouse; fig s7b
Jabara H, McDonald D, Janssen E, Massaad M, Ramesh N, Borzutzky A, et al. DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation. Nat Immunol. 2012;13:612-20 pubmed publisher
  • western blot; mouse; 1:1000; fig 1
  • western blot; rat; 1:1000; fig 2
Haas L, Salazar S, Kostylev M, Um J, Kaufman A, Strittmatter S. Metabotropic glutamate receptor 5 couples cellular prion protein to intracellular signalling in Alzheimer's disease. Brain. 2016;139:526-46 pubmed publisher
  • immunocytochemistry; mouse; 1:1000
Rolón-Reyes K, Kucheryavykh Y, Cubano L, Inyushin M, Skatchkov S, Eaton M, et al. Microglia Activate Migration of Glioma Cells through a Pyk2 Intracellular Pathway. PLoS ONE. 2015;10:e0131059 pubmed publisher
  • western blot; mouse; 1:1000; fig  1
Revuelta-López E, Cal R, Herraiz-Martínez A, de Gonzalo-Calvo D, Nasarre L, Roura S, et al. Hypoxia-driven sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) downregulation depends on low-density lipoprotein receptor-related protein 1 (LRP1)-signalling in cardiomyocytes. J Mol Cell Cardiol. 2015;85:25-36 pubmed publisher
  • western blot; human
Yoon H, Choi Y, Song J, Do I, Kang S, Ko Y, et al. Targeted inhibition of FAK, PYK2 and BCL-XL synergistically enhances apoptosis in ovarian clear cell carcinoma cell lines. PLoS ONE. 2014;9:e88587 pubmed publisher
product information
SKU :
3480S
Product-Name :
Pyk2 (5E2) Mouse mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M
Applications :
Immunoprecipitation
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
116
Host :
Mouse
Target :
Pyk2
Primary-Protein :
Pyk2
Alt-Names :
CADTK,CAK beta,CAK-beta,CAKB,Calcium-dependent tyrosine kinase,Cell adhesion kinase beta,FADK 2,FADK2,FAK2,Focal adhesion kinase 2,PKB,PTK,PTK2B,PTK2B protein tyrosine kinase 2 beta,PYK2,Proline-rich tyrosine kinase 2,Protein-tyrosine kinase 2-beta,RAFTK,Related adhesion focal tyrosine kinase,protein kinase B,protein tyrosine kinase 2 beta
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.