LATS1 (C66B5) Rabbit mAb | Cell Signaling Technology 3477S product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

LATS1 (C66B5) Rabbit mAb

catalog :

3477S

quantity :

100 ul

price :

235 USD

clonality :

monoclonal

host :

rabbit

reactivity :

human, mouse

application :

western blot, immunoprecipitation

more info or order :

Cell Signaling Technology product webpage

citations: 11

Published Application/Species/Dilution	Reference
western blot (knockdown validation); human; 1:1000; fig 1	Tumaneng K, Schlegelmilch K, Russell R, Yimlamai D, Basnet H, Mahadevan N, et al. YAP mediates crosstalk between the Hippo and PI(3)K–TOR pathways by suppressing PTEN via miR-29. Nat Cell Biol. 2012;14:1322-9 pubmed
western blot; mouse; fig 4	Nishio M, Sugimachi K, Goto H, Wang J, Morikawa T, Miyachi Y, et al. Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice. Proc Natl Acad Sci U S A. 2016;113:E71-80 pubmed publisher
western blot; human; fig 5	Dai X, Zhuang L, Wang D, Zhou T, Chang L, Gai R, et al. Nuclear translocation and activation of YAP by hypoxia contributes to the chemoresistance of SN38 in hepatocellular carcinoma cells. Oncotarget. 2016;7:6933-47 pubmed publisher
immunoprecipitation; mouse; 1:300-1:600; fig 5	Imajo M, Ebisuya M, Nishida E. Dual role of YAP and TAZ in renewal of the intestinal epithelium. Nat Cell Biol. 2015;17:7-19 pubmed publisher
western blot; human; 1:1000; fig 1	Mo J, Meng Z, Kim Y, Park H, Hansen C, Kim S, et al. Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway. Nat Cell Biol. 2015;17:500-10 pubmed publisher
western blot; human; 1:2000; fig 1	Meng Z, Moroishi T, Mottier-Pavie V, Plouffe S, Hansen C, Hong A, et al. MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway. Nat Commun. 2015;6:8357 pubmed publisher
western blot; mouse; 1:1000; fig 5	Iglesias-Bartolomé R, Torres D, Marone R, Feng X, Martin D, Simaan M, et al. Inactivation of a Gα(s)-PKA tumour suppressor pathway in skin stem cells initiates basal-cell carcinogenesis. Nat Cell Biol. 2015;17:793-803 pubmed publisher
western blot; mouse; fig 8	Liang N, Zhang C, Dill P, Panasyuk G, Pion D, Koka V, et al. Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex. J Exp Med. 2014;211:2249-63 pubmed publisher
western blot; human	Boin A, Couvelard A, Couderc C, Brito I, Filipescu D, Kalamarides M, et al. Proteomic screening identifies a YAP-driven signaling network linked to tumor cell proliferation in human schwannomas. Neuro Oncol. 2014;16:1196-209 pubmed publisher
	Habbig S, Bartram M, Müller R, Schwarz R, Andriopoulos N, Chen S, et al. NPHP4, a cilia-associated protein, negatively regulates the Hippo pathway. J Cell Biol. 2011;193:633-42 pubmed publisher
	Zhi X, Zhao D, Zhou Z, Liu R, Chen C. YAP promotes breast cell proliferation and survival partially through stabilizing the KLF5 transcription factor. Am J Pathol. 2012;180:2452-61 pubmed publisher

product information

SKU :

3477S

Product-Name :

LATS1 (C66B5) Rabbit mAb

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

H, M, Mk

Applications :

Immunoprecipitation

Product-Category :

Cell Cycle / Checkpoint Control

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

140

Host :

Rabbit

Target :

LATS1

Primary-Protein :

LATS1

Alt-Names :

LATS (large tumor suppressor, Drosophila) homolog 1,LATS, large tumor suppressor, homolog 1 (Drosophila),LATS1,Large tumor suppressor homolog 1,Serine/threonine-protein kinase LATS1,WARTS,WARTS protein kinase,h-warts,wts

more info or order :

Cell Signaling Technology product webpage