product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
HDAC1 (D5C6U) XP Rabbit mAb
catalog :
34589
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D5C6U
reactivity :
human, mouse
application :
western blot, western blot knockout validation
more info or order :
Cell Signaling Technology product webpage
citations: 8
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; loading ...; fig 6a
Aufhauser D, Hernandez P, Concors S, O Brien C, Wang Z, Murken D, et al. HDAC2 targeting stabilizes the CoREST complex in renal tubular cells and protects against renal ischemia/reperfusion injury. Sci Rep. 2021;11:9018 pubmed publisher
  • western blot; human; 1:1000; fig 5e
Zhao Z, Szczepanski A, Tsuboyama N, Abdala Valencia H, Goo Y, Singer B, et al. PAX9 Determines Epigenetic State Transition and Cell Fate in Cancer. Cancer Res. 2021;81:4696-4708 pubmed publisher
  • western blot; mouse; loading ...; fig 4d
Fang Y, Tang Y, Zhang Y, Pan Y, Jia J, Sun Z, et al. The H3K36me2 methyltransferase NSD1 modulates H3K27ac at active enhancers to safeguard gene expression. Nucleic Acids Res. 2021;49:6281-6295 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 6h
Luo L, Zhang Z, Qiu N, Ling L, Jia X, Song Y, et al. Disruption of FOXO3a-miRNA feedback inhibition of IGF2/IGF-1R/IRS1 signaling confers Herceptin resistance in HER2-positive breast cancer. Nat Commun. 2021;12:2699 pubmed publisher
  • western blot; mouse; 1:2000; loading ...; fig 1b
Mondal B, Jin H, Kallappagoudar S, Sedkov Y, Martinez T, Sentmanat M, et al. The histone deacetylase complex MiDAC regulates a neurodevelopmental gene expression program to control neurite outgrowth. elife. 2020;9: pubmed publisher
  • western blot; human; loading ...; fig s1
Bainor A, Saini S, Calderon A, Casado Polanco R, Giner Ramirez B, Moncada C, et al. The HDAC-Associated Sin3B Protein Represses DREAM Complex Targets and Cooperates with APC/C to Promote Quiescence. Cell Rep. 2018;25:2797-2807.e8 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 6e
Wang Y, Zhang J, Su Y, Shen Y, Jiang D, Hou Y, et al. G9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin. Nat Commun. 2017;8:274 pubmed publisher
Gruber W, Peer E, Elmer D, Sternberg C, Tesanovic S, Del Burgo P, et al. Targeting class I histone deacetylases by the novel small molecule inhibitor 4SC-202 blocks oncogenic hedgehog-GLI signaling and overcomes smoothened inhibitor resistance. Int J Cancer. 2018;142:968-975 pubmed publisher
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.