MeCP2 (D4F3) XP® Rabbit mAb | Cell Signaling Technology 3456P product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

MeCP2 (D4F3) XP® Rabbit mAb

catalog :

3456P

quantity :

40 ul

price :

135 USD

clonality :

monoclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - frozen section

more info or order :

Cell Signaling Technology product webpage

citations: 9

Published Application/Species/Dilution	Reference
immunohistochemistry - frozen section; mouse; fig 1 immunohistochemistry (knockout validation); mouse; fig 1 western blot (knockout validation); mouse; fig 4	Tsuchiya Y, Minami Y, Umemura Y, Watanabe H, Ono D, Nakamura W, et al. Disruption of MeCP2 attenuates circadian rhythm in CRISPR/Cas9-based Rett syndrome model mouse. Genes Cells. 2015;20:992-1005 pubmed publisher
immunocytochemistry; mouse; 1:500; fig 3	Kishi N, MacDonald J, Ye J, Molyneaux B, Azim E, Macklis J. Reduction of aberrant NF-κB signalling ameliorates Rett syndrome phenotypes in Mecp2-null mice. Nat Commun. 2016;7:10520 pubmed publisher
immunohistochemistry; mouse; 1:200; fig 1	Bedogni F, Cobolli Gigli C, Pozzi D, Rossi R, Scaramuzza L, Rossetti G, et al. Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms. Cereb Cortex. 2016;26:2517-29 pubmed publisher
immunoprecipitation; mouse; fig 2 western blot; mouse; 1:10,000; fig 2	Tai D, Liu Y, Hsu W, Ma Y, Cheng S, Liu S, et al. MeCP2 SUMOylation rescues Mecp2-mutant-induced behavioural deficits in a mouse model of Rett syndrome. Nat Commun. 2016;7:10552 pubmed publisher
western blot; mouse; fig 1c	Krishnan N, Krishnan K, Connors C, Choy M, Page R, Peti W, et al. PTP1B inhibition suggests a therapeutic strategy for Rett syndrome. J Clin Invest. 2015;125:3163-77 pubmed publisher
western blot; mouse; 1:1000; fig 2	Conti V, Gandaglia A, Galli F, Tirone M, Bellini E, Campana L, et al. MeCP2 Affects Skeletal Muscle Growth and Morphology through Non Cell-Autonomous Mechanisms. PLoS ONE. 2015;10:e0130183 pubmed publisher
western blot; human; 1:1000	Cheng J, Huang M, Zhu Y, Xin Y, Zhao Y, Huang J, et al. SUMOylation of MeCP2 is essential for transcriptional repression and hippocampal synapse development. J Neurochem. 2014;128:798-806 pubmed publisher
	Brendel C, Belakhov V, Werner H, Wegener E, Gartner J, Nudelman I, et al. Readthrough of nonsense mutations in Rett syndrome: evaluation of novel aminoglycosides and generation of a new mouse model. J Mol Med (Berl). 2011;89:389-98 pubmed publisher
	Bihaqi S, Zawia N. Alzheimer's disease biomarkers and epigenetic intermediates following exposure to Pb in vitro. Curr Alzheimer Res. 2012;9:555-62 pubmed

product information

SKU :

3456P

Product-Name :

MeCP2 (D4F3) XP® Rabbit mAb

Size :

40 ul

Price-(USD) :

135 USD

Species-x-Reactivity :

H, M, R, Mk

Applications :

Immunofluorescence (Immunocytochemistry)

Product-Category :

Chromatin Regulation / Nuclear Function

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

Host :

Rabbit

Target :

MeCP2

Primary-Protein :

MeCP2

Alt-Names :

AUTSX3,DKFZp686A24160,MECP2,MRX16,MRX79,MRXS13,MRXSL,MeCp-2 protein,Methyl-CpG-binding protein 2,PPMX,RS,RTS,RTT,methyl CpG binding protein 2 (Rett syndrome)

more info or order :

Cell Signaling Technology product webpage