product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-DRP1 (Ser616) Antibody
catalog :
3455S
quantity :
100 ul
price :
274 USD
clonality :
polyclonal
host :
rabbit
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, flow cytometry
more info or order :
Cell Signaling Technology product webpage
citations: 14
Published Application/Species/DilutionReference
  • western blot; mouse; fig s2
Korwitz A, Merkwirth C, Richter-Dennerlein R, Tröder S, Sprenger H, Quirós P, et al. Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria. J Cell Biol. 2016;212:157-66 pubmed publisher
  • western blot; mouse; 1:800; fig 4
Kumari S, Mehta S, Milledge G, Huang X, Li H, Li P. Ubisol-Q10 Prevents Glutamate-Induced Cell Death by Blocking Mitochondrial Fragmentation and Permeability Transition Pore Opening. Int J Biol Sci. 2016;12:688-700 pubmed publisher
  • western blot; human; fig 4
Suzuki-Karasaki Y, Fujiwara K, Saito K, Suzuki-Karasaki M, Ochiai T, Soma M. Distinct effects of TRAIL on the mitochondrial network in human cancer cells and normal cells: role of plasma membrane depolarization. Oncotarget. 2015;6:21572-88 pubmed
  • western blot; mouse
  • immunocytochemistry; mouse
Gorbunov N, McDaniel D, Zhai M, Liao P, Garrison B, Kiang J. Autophagy and mitochondrial remodelling in mouse mesenchymal stromal cells challenged with Staphylococcus epidermidis. J Cell Mol Med. 2015;19:1133-50 pubmed publisher
  • western blot; mouse
Picard M, Azuelos I, Jung B, Giordano C, Matecki S, Hussain S, et al. Mechanical ventilation triggers abnormal mitochondrial dynamics and morphology in the diaphragm. J Appl Physiol (1985). 2015;118:1161-71 pubmed publisher
  • western blot; human; 1:500; fig 7
Li G, Zhou J, Budhraja A, Hu X, Chen Y, Cheng Q, et al. Mitochondrial translocation and interaction of cofilin and Drp1 are required for erucin-induced mitochondrial fission and apoptosis. Oncotarget. 2015;6:1834-49 pubmed
  • western blot; rat; 1:1000; fig 3
Rutkai I, Katakam P, Dutta S, Busija D. Sustained mitochondrial functioning in cerebral arteries after transient ischemic stress in the rat: a potential target for therapies. Am J Physiol Heart Circ Physiol. 2014;307:H958-66 pubmed publisher
  • western blot; human
Lee J, Kapur M, Li M, Choi M, Choi S, Kim H, et al. MFN1 deacetylation activates adaptive mitochondrial fusion and protects metabolically challenged mitochondria. J Cell Sci. 2014;127:4954-63 pubmed publisher
  • western blot; mouse; 1:1000
Ribeiro M, Rosenstock T, Oliveira A, Oliveira C, Rego A. Insulin and IGF-1 improve mitochondrial function in a PI-3K/Akt-dependent manner and reduce mitochondrial generation of reactive oxygen species in Huntington's disease knock-in striatal cells. Free Radic Biol Med. 2014;74:129-44 pubmed publisher
  • western blot; mouse; 1:1000
Faccenda D, Tan C, Seraphim A, Duchen M, Campanella M. IF1 limits the apoptotic-signalling cascade by preventing mitochondrial remodelling. Cell Death Differ. 2013;20:686-97 pubmed publisher
Sharp W, Fang Y, Han M, Zhang H, Hong Z, Banathy A, et al. Dynamin-related protein 1 (Drp1)-mediated diastolic dysfunction in myocardial ischemia-reperfusion injury: therapeutic benefits of Drp1 inhibition to reduce mitochondrial fission. FASEB J. 2014;28:316-26 pubmed publisher
Merrill R, Dagda R, Dickey A, Cribbs J, Green S, Usachev Y, et al. Mechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1. PLoS Biol. 2011;9:e1000612 pubmed publisher
Rambold A, Kostelecky B, Elia N, Lippincott-Schwartz J. Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation. Proc Natl Acad Sci U S A. 2011;108:10190-5 pubmed publisher
Kashatus D, Lim K, Brady D, Pershing N, Cox A, Counter C. RALA and RALBP1 regulate mitochondrial fission at mitosis. Nat Cell Biol. 2011;13:1108-15 pubmed publisher
product information
SKU :
3455S
Product-Name :
Phospho-DRP1 (Ser616) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, (M, R, Mk)
Applications :
Flow cytometry
Product-Category :
Cytoskeletal Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
78-82
Host :
Rabbit
Target :
DRP1 (Ser616) phosphate
Primary-Protein :
DRP1
Alt-Names :
DLP1,DNM1L,DRP1,DVLP,DYNIV-11,Dnm1p/Vps1p-like protein,Dymple,Dynamin family member proline-rich carboxyl-terminal domain less,Dynamin-1-like protein,Dynamin-like protein,Dynamin-like protein 4,Dynamin-like protein IV,Dynamin-related protein 1,FLJ41912,HdynIV,VPS1,dynamin 1-like
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.