product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
PSD95 (D27E11) XP® Rabbit mAb
catalog :
3450
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D27E11
reactivity :
human, mouse, rat, chicken
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section
citations: 32
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:2000; loading ...; fig 2b
Mohammad H, Marchisella F, Ortega Martinez S, Hollos P, Eerola K, Komulainen E, et al. JNK1 controls adult hippocampal neurogenesis and imposes cell-autonomous control of anxiety behaviour from the neurogenic niche. Mol Psychiatry. 2018;23:362-374 pubmed publisher
  • immunocytochemistry; mouse; 1:200; loading ...; fig 7b
Zhao Y, Tian J, Sui S, Yuan X, Chen H, Qu C, et al. Loss of succinyl-CoA synthase ADP-forming β subunit disrupts mtDNA stability and mitochondrial dynamics in neurons. Sci Rep. 2017;7:7169 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 2b
Sodero A, Rodríguez Silva M, Salio C, Sassoè Pognetto M, Chambers J. Sab is differentially expressed in the brain and affects neuronal activity. Brain Res. 2017;1670:76-85 pubmed publisher
  • immunohistochemistry; human; 1:200; fig s10d
Birey F, Andersen J, Makinson C, Islam S, Wei W, Huber N, et al. Assembly of functionally integrated human forebrain spheroids. Nature. 2017;545:54-59 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 3e
Kwon M, Han J, Kim U, Cha M, Um S, Bai S, et al. Inhibition of Mammalian Target of Rapamycin (mTOR) Signaling in the Insular Cortex Alleviates Neuropathic Pain after Peripheral Nerve Injury. Front Mol Neurosci. 2017;10:79 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 2a
Shapiro L, Parsons R, Koleske A, Gourley S. Differential expression of cytoskeletal regulatory factors in the adolescent prefrontal cortex: Implications for cortical development. J Neurosci Res. 2017;95:1123-1143 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 1f
Zhang H, Sun S, Wu L, Pchitskaya E, Zakharova O, Fon Tacer K, et al. Store-Operated Calcium Channel Complex in Postsynaptic Spines: A New Therapeutic Target for Alzheimer's Disease Treatment. J Neurosci. 2016;36:11837-11850 pubmed
  • immunohistochemistry; mouse; loading ...; fig 3b
Park K, Ribic A, Laage Gaupp F, Coman D, Huang Y, Dulla C, et al. Excitatory Synaptic Drive and Feedforward Inhibition in the Hippocampal CA3 Circuit Are Regulated by SynCAM 1. J Neurosci. 2016;36:7464-75 pubmed publisher
  • immunocytochemistry; mouse; 1:200; fig 3
Beck S, Guo L, Phensy A, Tian J, Wang L, Tandon N, et al. Deregulation of mitochondrial F1FO-ATP synthase via OSCP in Alzheimer's disease. Nat Commun. 2016;7:11483 pubmed publisher
  • western blot; rat; fig 6
Furman J, Sompol P, Kraner S, Pleiss M, Putman E, Dunkerson J, et al. Blockade of Astrocytic Calcineurin/NFAT Signaling Helps to Normalize Hippocampal Synaptic Function and Plasticity in a Rat Model of Traumatic Brain Injury. J Neurosci. 2016;36:1502-15 pubmed publisher
  • western blot; mouse; 1:1000; fig 3d
Ageta Ishihara N, Yamazaki M, Konno K, Nakayama H, Abe M, Hashimoto K, et al. A CDC42EP4/septin-based perisynaptic glial scaffold facilitates glutamate clearance. Nat Commun. 2015;6:10090 pubmed publisher
  • western blot; mouse; 1:10,000; fig 4
Forrest C, McNair K, Pisar M, Khalil O, Darlington L, Stone T. Altered hippocampal plasticity by prenatal kynurenine administration, kynurenine-3-monoxygenase (KMO) deletion or galantamine. Neuroscience. 2015;310:91-105 pubmed publisher
  • western blot; rat; 1:1000; fig 4
Zhou J, Liu Z, Yu J, Han X, Fan S, Shao W, et al. Quantitative Proteomic Analysis Reveals Molecular Adaptations in the Hippocampal Synaptic Active Zone of Chronic Mild Stress-Unsusceptible Rats. Int J Neuropsychopharmacol. 2015;19: pubmed publisher
  • western blot; mouse; 1:1000; fig 6
Popugaeva E, Pchitskaya E, Speshilova A, Alexandrov S, Zhang H, Vlasova O, et al. STIM2 protects hippocampal mushroom spines from amyloid synaptotoxicity. Mol Neurodegener. 2015;10:37 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 3n
Johnson V, Xiang M, Chen Z, Junge H. Neurite Mistargeting and Inverse Order of Intraretinal Vascular Plexus Formation Precede Subretinal Vascularization in Vldlr Mutant Mice. PLoS ONE. 2015;10:e0132013 pubmed publisher
  • immunocytochemistry; mouse; 1:100
  • western blot; mouse; 1:2000
Ferreira J, Schmidt J, Rio P, Águas R, Rooyakkers A, Li K, et al. GluN2B-Containing NMDA Receptors Regulate AMPA Receptor Traffic through Anchoring of the Synaptic Proteasome. J Neurosci. 2015;35:8462-79 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 5f
  • western blot; mouse; 1:1000; loading ...; fig 5d
Bhatt D, Puig K, Gorr M, Wold L, Combs C. A pilot study to assess effects of long-term inhalation of airborne particulate matter on early Alzheimer-like changes in the mouse brain. PLoS ONE. 2015;10:e0127102 pubmed publisher
  • western blot; chicken; 1:2000; fig 1
Goyer D, Fensky L, Hilverling A, Kurth S, Kuenzel T. Expression of the postsynaptic scaffold PSD-95 and development of synaptic physiology during giant terminal formation in the auditory brainstem of the chicken. Eur J Neurosci. 2015;41:1416-29 pubmed publisher
  • western blot; human; 1:1000; fig 2a
Machado C, Griesi Oliveira K, Rosenberg C, Kok F, Martins S, Passos Bueno M, et al. Collybistin binds and inhibits mTORC1 signaling: a potential novel mechanism contributing to intellectual disability and autism. Eur J Hum Genet. 2016;24:59-65 pubmed publisher
  • western blot; human; fig 9
Tran Q, Vermeer M, Burgard M, Hassan A, Giles J. Hetero-oligomeric Complex between the G Protein-coupled Estrogen Receptor 1 and the Plasma Membrane Ca2+-ATPase 4b. J Biol Chem. 2015;290:13293-307 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:100; fig s8
Saunders A, Oldenburg I, Berezovskii V, Johnson C, Kingery N, Elliott H, et al. A direct GABAergic output from the basal ganglia to frontal cortex. Nature. 2015;521:85-9 pubmed publisher
  • western blot; rat; 1:1000
Pérez Alvarez M, Mateos L, Alonso A, Wandosell F. Estradiol and Progesterone Administration After pMCAO Stimulates the Neurological Recovery and Reduces the Detrimental Effect of Ischemia Mainly in Hippocampus. Mol Neurobiol. 2015;52:1690-1703 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:200
Leal G, Afonso P, Duarte C. Neuronal activity induces synaptic delivery of hnRNP A2/B1 by a BDNF-dependent mechanism in cultured hippocampal neurons. PLoS ONE. 2014;9:e108175 pubmed publisher
  • western blot; mouse; 1:1000
Qiu S, Zhang M, Liu Y, Guo Y, Zhao H, Song Q, et al. GluA1 phosphorylation contributes to postsynaptic amplification of neuropathic pain in the insular cortex. J Neurosci. 2014;34:13505-15 pubmed publisher
  • western blot; mouse; 1:500
Gruol D, Vo K, Bray J, Roberts A. CCL2-ethanol interactions and hippocampal synaptic protein expression in a transgenic mouse model. Front Integr Neurosci. 2014;8:29 pubmed publisher
  • immunohistochemistry; mouse; 1:500
Jalewa J, Joshi A, McGinnity T, Prasad G, Wong Lin K, Holscher C. Neural circuit interactions between the dorsal raphe nucleus and the lateral hypothalamus: an experimental and computational study. PLoS ONE. 2014;9:e88003 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200
Soiza Reilly M, Commons K. Quantitative analysis of glutamatergic innervation of the mouse dorsal raphe nucleus using array tomography. J Comp Neurol. 2011;519:3802-14 pubmed publisher
Kouloulia S, Hallin E, Simbriger K, Amorim I, Lach G, Amvrosiadis T, et al. Raptor-Mediated Proteasomal Degradation of Deamidated 4E-BP2 Regulates Postnatal Neuronal Translation and NF-κB Activity. Cell Rep. 2019;29:3620-3635.e7 pubmed publisher
Pluvinage J, Haney M, Smith B, Sun J, Iram T, Bonanno L, et al. CD22 blockade restores homeostatic microglial phagocytosis in ageing brains. Nature. 2019;568:187-192 pubmed publisher
Uddin M, Unda B, Kwan V, Holzapfel N, White S, Chalil L, et al. OTUD7A Regulates Neurodevelopmental Phenotypes in the 15q13.3 Microdeletion Syndrome. Am J Hum Genet. 2018;102:278-295 pubmed publisher
Wang Y, Fehlhaber K, Sarria I, Cao Y, Ingram N, Guerrero Given D, et al. The Auxiliary Calcium Channel Subunit α2δ4 Is Required for Axonal Elaboration, Synaptic Transmission, and Wiring of Rod Photoreceptors. Neuron. 2017;93:1359-1374.e6 pubmed publisher
Wang G, Smith S, Mourrain P. Sub-synaptic, multiplexed analysis of proteins reveals Fragile X related protein 2 is mislocalized in Fmr1 KO synapses. elife. 2016;5: pubmed publisher
product information
SKU :
3450S
Product-Name :
PSD95 (D27E11) XP® Rabbit mAb
Size :
100 ul
Price-(USD) :
260 USD
Species-x-Reactivity :
H, M, R
Applications :
Immunofluorescence (Frozen)
Product-Category :
Neuroscience
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
95
Host :
Rabbit
Target :
PSD-95
Primary-Protein :
PSD-95
Alt-Names :
DLG4,Disks large homolog 4,FLJ97752,FLJ98574,PSD-95,PSD95,Postsynaptic density protein 95,SAP-90,SAP90,Synapse-associated protein 90,Tax interaction protein 15,discs large homolog 4,discs, large homolog 4 (Drosophila),post-synaptic density protein 95
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.