product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-HDAC4 (Ser246)/HDAC5 (Ser259)/HDAC7 (Ser155) (D27B5) Rabbit mAb
catalog :
3443
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
clone name :
D27B5
reactivity :
human, mouse
application :
western blot, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 14
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 6a
Zhong G, Zhao D, Li J, Liu Z, Pan J, Yuan X, et al. WWP1 Deficiency Alleviates Cardiac Remodeling Induced by Simulated Microgravity. Front Cell Dev Biol. 2021;9:739944 pubmed publisher
  • western blot; mouse; 1:1500; loading ...; fig 4a
Guo Y, Yu Z, Wu J, Gong H, Kesteven S, Iismaa S, et al. The Ca2+-activated cation channel TRPM4 is a positive regulator of pressure overload-induced cardiac hypertrophy. elife. 2021;10: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 5g
Zhao D, Zhong G, Li J, Pan J, Zhao Y, Song H, et al. Targeting E3 Ubiquitin-Ligase WWP1 Prevents Cardiac Hypertrophy Through Destabilizing DVL2 via Inhibition of K27-Linked Ubiquitination. Circulation. 2021;: pubmed publisher
  • western blot; human; fig s1j
Di Giorgio E, Paluvai H, Dalla E, Ranzino L, Renzini A, Moresi V, et al. HDAC4 degradation during senescence unleashes an epigenetic program driven by AP-1/p300 at selected enhancers and super-enhancers. Genome Biol. 2021;22:129 pubmed publisher
  • western blot; human; loading ...; fig 7e
Sonntag T, Moresco J, Yates J, Montminy M. The KLDpT activation loop motif is critical for MARK kinase activity. PLoS ONE. 2019;14:e0225727 pubmed publisher
  • western blot; mouse; 1:2000; loading ...; fig 5a
Chen S, Zhang Q, Bai B, Ouyang S, Bao Y, Li H, et al. MARK2/Par1b Insufficiency Attenuates DVL Gene Transcription via Histone Deacetylation in Lumbosacral Spina Bifida. Mol Neurobiol. 2017;54:6304-6316 pubmed publisher
  • western blot; mouse
Taglieri D, Johnson K, Burmeister B, Monasky M, Spindler M, DeSantiago J, et al. The C-terminus of the long AKAP13 isoform (AKAP-Lbc) is critical for development of compensatory cardiac hypertrophy. J Mol Cell Cardiol. 2014;66:27-40 pubmed publisher
Barber K, Muir P, Szeligowski R, Rogulina S, Gerstein M, Sampson J, et al. Encoding human serine phosphopeptides in bacteria for proteome-wide identification of phosphorylation-dependent interactions. Nat Biotechnol. 2018;36:638-644 pubmed publisher
Tarumoto Y, Lu B, Somerville T, Huang Y, Milazzo J, Wu X, et al. LKB1, Salt-Inducible Kinases, and MEF2C Are Linked Dependencies in Acute Myeloid Leukemia. Mol Cell. 2018;69:1017-1027.e6 pubmed publisher
Kishore A, Liang H, Kanchwala M, Xing C, Ganesh T, Akgul Y, et al. Prostaglandin dehydrogenase is a target for successful induction of cervical ripening. Proc Natl Acad Sci U S A. 2017;114:E6427-E6436 pubmed publisher
Meng Z, Gong J, Chen Z, Sun J, Xiao Y, Wang L, et al. Glucose Sensing by Skeletal Myocytes Couples Nutrient Signaling to Systemic Homeostasis. Mol Cell. 2017;66:332-344.e4 pubmed publisher
Zhong G, Li Y, Li H, Sun W, Cao D, Li J, et al. Simulated Microgravity and Recovery-Induced Remodeling of the Left and Right Ventricle. Front Physiol. 2016;7:274 pubmed publisher
Mihaylova M, Vasquez D, Ravnskjaer K, Denechaud P, Yu R, Alvarez J, et al. Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis. Cell. 2011;145:607-21 pubmed publisher
Zhang L, Jin M, Margariti A, Wang G, Luo Z, Zampetaki A, et al. Sp1-dependent activation of HDAC7 is required for platelet-derived growth factor-BB-induced smooth muscle cell differentiation from stem cells. J Biol Chem. 2010;285:38463-72 pubmed publisher
product information
SKU :
3443S
Product-Name :
Phospho-HDAC4 (Ser246)/HDAC5 (Ser259)/HDAC7 (Ser155) (D27B5) Rabbit mAb
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M
Applications :
Immunoprecipitation
Product-Category :
Chromatin Regulation / Nuclear Function
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
140, 124, 120
Host :
Rabbit
Target :
HDAC4 (Ser246) phosphate/HDAC5 (Ser259) phosphate/HDAC7 (Ser155) phosphate
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.