Hydroxy-HIF-1α (Pro564) (D43B5) XP® Rabbit mAb | Cell Signaling Technology 3434S product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Hydroxy-HIF-1α (Pro564) (D43B5) XP® Rabbit mAb

catalog :

3434S

quantity :

100 ul

price :

301 USD

clonality :

monoclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunoprecipitation

more info or order :

Cell Signaling Technology product webpage

citations: 9

Published Application/Species/Dilution	Reference
western blot; human; 1:1000; fig 4	Ortmann B, Bensaddek D, Carvalhal S, Moser S, Mudie S, Griffis E, et al. CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells. J Cell Sci. 2016;129:191-205 pubmed publisher
western blot; mouse; 1:1000; fig hydroxy proline (3434S, Cell Signaling; 1:1,000)	Karuppagounder S, Alim I, Khim S, Bourassa M, Sleiman S, John R, et al. Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models. Sci Transl Med. 2016;8:328ra29 pubmed publisher
western blot; human; 1:1000; fig 3	Ma B, Chen Y, Chen L, Cheng H, Mu C, Li J, et al. Hypoxia regulates Hippo signalling through the SIAH2 ubiquitin E3 ligase. Nat Cell Biol. 2015;17:95-103 pubmed publisher
western blot; human; 1:1000	Sun Y, George J, Rocha S. Dose-dependent effects of allopurinol on human foreskin fibroblast cells and human umbilical vein endothelial cells under hypoxia. PLoS ONE. 2015;10:e0123649 pubmed publisher
western blot; human; fig 2a	Zheng X, Zhai B, Koivunen P, Shin S, Lu G, Liu J, et al. Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase. Genes Dev. 2014;28:1429-44 pubmed publisher
	Chan M, Atasoylu O, Hodson E, Tumber A, Leung I, Chowdhury R, et al. Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain. PLoS ONE. 2015;10:e0132004 pubmed publisher
	Snell C, Turley H, McIntyre A, Li D, Masiero M, Schofield C, et al. Proline-hydroxylated hypoxia-inducible factor 1α (HIF-1α) upregulation in human tumours. PLoS ONE. 2014;9:e88955 pubmed publisher
	Ohara T, Noma K, Urano S, Watanabe S, Nishitani S, Tomono Y, et al. A novel synergistic effect of iron depletion on antiangiogenic cancer therapy. Int J Cancer. 2013;132:2705-13 pubmed publisher
	Tian Y, Yeoh K, Lee M, Eriksson T, Kessler B, Kramer H, et al. Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors. J Biol Chem. 2011;286:13041-51 pubmed publisher

product information

SKU :

3434S

Product-Name :

Hydroxy-HIF-1α (Pro564) (D43B5) XP® Rabbit mAb

Size :

100 ul

Price-(USD) :

301 USD

Species-x-Reactivity :

H, (M, R, Mk, C, X, Z, Pg)

Applications :

Immunofluorescence (Immunocytochemistry)

Product-Category :

Developmental Biology

Shipping-Temp :

COLD

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

120

Host :

Rabbit

Target :

HIF1A (Pro564) hydroxylate

Primary-Protein :

HIF1A

Alt-Names :

ARNT interacting protein,ARNT-interacting protein,BHLHE78,Basic-helix-loop-helix-PAS protein MOP1,Class E basic helix-loop-helix protein 78,HIF-1-alpha,HIF-1alpha,HIF1,HIF1-alpha,HIF1A,Hypoxia-inducible factor 1-alpha,MOP1,Member of PAS protein 1,PAS domain-containing protein 8,PASD8,hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor),hypoxia-inducible factor 1 alpha isoform I.3,hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor),member of PAS superfamily 1

more info or order :

Cell Signaling Technology product webpage