product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Hydroxy-HIF-1α (Pro564) (D43B5) XP® Rabbit mAb
catalog :
3434P
quantity :
40 ul
price :
135 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 7
Published Application/Species/DilutionReference
  • western blot; human; 1:1000; fig 4
Ortmann B, Bensaddek D, Carvalhal S, Moser S, Mudie S, Griffis E, et al. CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells. J Cell Sci. 2016;129:191-205 pubmed publisher
  • western blot; human; 1:1000; fig 3
Ma B, Chen Y, Chen L, Cheng H, Mu C, Li J, et al. Hypoxia regulates Hippo signalling through the SIAH2 ubiquitin E3 ligase. Nat Cell Biol. 2015;17:95-103 pubmed publisher
  • western blot; human; 1:1000
Sun Y, George J, Rocha S. Dose-dependent effects of allopurinol on human foreskin fibroblast cells and human umbilical vein endothelial cells under hypoxia. PLoS ONE. 2015;10:e0123649 pubmed publisher
  • western blot; human; fig 2a
Zheng X, Zhai B, Koivunen P, Shin S, Lu G, Liu J, et al. Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase. Genes Dev. 2014;28:1429-44 pubmed publisher
Li B, Iglesias-Pedraz J, Chen L, Yin F, Cadenas E, Reddy S, et al. Downregulation of the Werner syndrome protein induces a metabolic shift that compromises redox homeostasis and limits proliferation of cancer cells. Aging Cell. 2014;13:367-78 pubmed
Ohara T, Noma K, Urano S, Watanabe S, Nishitani S, Tomono Y, et al. A novel synergistic effect of iron depletion on antiangiogenic cancer therapy. Int J Cancer. 2013;132:2705-13 pubmed publisher
Tian Y, Yeoh K, Lee M, Eriksson T, Kessler B, Kramer H, et al. Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors. J Biol Chem. 2011;286:13041-51 pubmed publisher
product information
SKU :
3434P
Product-Name :
Hydroxy-HIF-1α (Pro564) (D43B5) XP® Rabbit mAb
Size :
40 ul
Price-(USD) :
135 USD
Species-x-Reactivity :
H, (M, R, Mk, C, X, Z, Pg)
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Developmental Biology
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
120
Host :
Rabbit
Target :
HIF1A (Pro564) hydroxylate
Primary-Protein :
HIF1A
Alt-Names :
ARNT interacting protein,ARNT-interacting protein,BHLHE78,Basic-helix-loop-helix-PAS protein MOP1,Class E basic helix-loop-helix protein 78,HIF-1-alpha,HIF-1alpha,HIF1,HIF1-alpha,HIF1A,Hypoxia-inducible factor 1-alpha,MOP1,Member of PAS protein 1,PAS domain-containing protein 8,PASD8,hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor),hypoxia-inducible factor 1 alpha isoform I.3,hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor),member of PAS superfamily 1
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.