product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
RhoC (D40E4) Rabbit mAb
catalog :
3430
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D40E4
reactivity :
human, mouse, rat
application :
western blot
more info or order :
Cell Signaling Technology product webpage
citations: 18
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:200; loading ...; fig 6h
Fayad R, Rojas M, Partisani M, Finetti P, Dib S, Abélanet S, et al. EFA6B regulates a stop signal for collective invasion in breast cancer. Nat Commun. 2021;12:2198 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3b, 3c
Jiang X, Xu Y, Ren H, Jiang J, Wudu M, Wang Q, et al. KLHL18 inhibits the proliferation, migration, and invasion of non-small cell lung cancer by inhibiting PI3K/PD-L1 axis activity. Cell Biosci. 2020;10:139 pubmed publisher
  • western blot; human; 1:500; loading ...; fig s5f
Sun T, Yang L, Kaur H, Pestel J, Looso M, Nolte H, et al. A reverse signaling pathway downstream of Sema4A controls cell migration via Scrib. J Cell Biol. 2017;216:199-215 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 1d
Haak A, Appleton K, Lisabeth E, Misek S, Ji Y, Wade S, et al. Pharmacological Inhibition of Myocardin-related Transcription Factor Pathway Blocks Lung Metastases of RhoC-Overexpressing Melanoma. Mol Cancer Ther. 2017;16:193-204 pubmed publisher
  • western blot; human; fig 4
Bianchi Smiraglia A, Bagati A, Fink E, Moparthy S, Wawrzyniak J, Marvin E, et al. Microphthalmia-associated transcription factor suppresses invasion by reducing intracellular GTP pools. Oncogene. 2017;36:84-96 pubmed publisher
  • western blot; human; fig 1
Marcos Ramiro B, García Weber D, Barroso S, Feito J, Ortega M, Cernuda Morollón E, et al. RhoB controls endothelial barrier recovery by inhibiting Rac1 trafficking to the cell border. J Cell Biol. 2016;213:385-402 pubmed publisher
  • western blot; human; loading ...; fig 6c
Wynn M, Yates J, Evans C, Van Wassenhove L, Wu Z, Bridges S, et al. RhoC GTPase Is a Potent Regulator of Glutamine Metabolism and N-Acetylaspartate Production in Inflammatory Breast Cancer Cells. J Biol Chem. 2016;291:13715-29 pubmed publisher
  • western blot; human; fig 1
Bzymek R, Horsthemke M, Isfort K, Mohr S, Tjaden K, Muller Tidow C, et al. Real-time two- and three-dimensional imaging of monocyte motility and navigation on planar surfaces and in collagen matrices: roles of Rho. Sci Rep. 2016;6:25016 pubmed publisher
  • western blot; human; loading ...; fig 4b
Falkenberg N, Anastasov N, Schaub A, Radulovic V, Schmitt M, Magdolen V, et al. Secreted uPAR isoform 2 (uPAR7b) is a novel direct target of miR-221. Oncotarget. 2015;6:8103-14 pubmed
  • western blot; human; fig 3
Xing Z, Lin A, Li C, Liang K, Wang S, Liu Y, et al. lncRNA directs cooperative epigenetic regulation downstream of chemokine signals. Cell. 2014;159:1110-1125 pubmed publisher
  • western blot; human; 1:1000
Del Galdo S, Vettel C, Heringdorf D, Wieland T. The activation of RhoC in vascular endothelial cells is required for the S1P receptor type 2-induced inhibition of angiogenesis. Cell Signal. 2013;25:2478-84 pubmed publisher
  • western blot; human; fig 1
Kreßner C, Nollau P, Grosse R, Brandt D. Functional interaction of SCAI with the SWI/SNF complex for transcription and tumor cell invasion. PLoS ONE. 2013;8:e69947 pubmed publisher
  • western blot; human; fig 6, 7
Nakayama I, Shibazaki M, Yashima Abo A, Miura F, Sugiyama T, Masuda T, et al. Loss of HOXD10 expression induced by upregulation of miR-10b accelerates the migration and invasion activities of ovarian cancer cells. Int J Oncol. 2013;43:63-71 pubmed publisher
Arsic N, Ho Pun Cheung A, Lopez Crapez E, Assenat E, Jarlier M, Anguille C, et al. The p53 isoform delta133p53ß regulates cancer cell apoptosis in a RhoB-dependent manner. PLoS ONE. 2017;12:e0172125 pubmed publisher
Mardakheh F, Self A, Marshall C. RHO binding to FAM65A regulates Golgi reorientation during cell migration. J Cell Sci. 2016;129:4466-4479 pubmed
Worzfeld T, Swiercz J, Looso M, Straub B, Sivaraj K, Offermanns S. ErbB-2 signals through Plexin-B1 to promote breast cancer metastasis. J Clin Invest. 2012;122:1296-305 pubmed publisher
Arsic N, Bendris N, Peter M, Begon Pescia C, Rebouissou C, Gadea G, et al. A novel function for Cyclin A2: control of cell invasion via RhoA signaling. J Cell Biol. 2012;196:147-62 pubmed publisher
Thumkeo D, Shinohara R, Watanabe K, Takebayashi H, Toyoda Y, Tohyama K, et al. Deficiency of mDia, an actin nucleator, disrupts integrity of neuroepithelium and causes periventricular dysplasia. PLoS ONE. 2011;6:e25465 pubmed publisher
product information
SKU :
3430S
Product-Name :
RhoC (D40E4) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, Mk, (R)
Applications :
Western blot
Product-Category :
Cytoskeletal Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
21
Host :
Rabbit
Target :
RhoC
Primary-Protein :
RhoC
Alt-Names :
ARH9,ARHC,MGC1448,MGC61427,RAS-related homolog 9,RHOC,RHOH9,Rho cDNA clone 9,Rho-related GTP-binding protein RhoC,h9,oncogene RHO H9,ras homolog gene family, member C,rhoC GTPase,small GTP binding protein RhoC
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.