product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
eIF3A (D51F4) XP® Rabbit mAb
catalog :
3411
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
D51F4
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 7
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:2000; loading ...; fig 3a
Shi H, Wang X, Lu Z, Zhao B, Ma H, Hsu P, et al. YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA. Cell Res. 2017;27:315-328 pubmed publisher
  • immunocytochemistry; human; 1:1000
Sidrauski C, McGeachy A, Ingolia N, Walter P. The small molecule ISRIB reverses the effects of eIF2α phosphorylation on translation and stress granule assembly. elife. 2015;4: pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 2f
Li X, Wu Y, Li X, Li D, Du J, Hu C, et al. Role of eukaryotic translation initiation factor 3a in bleomycin-induced pulmonary fibrosis. Eur J Pharmacol. 2015;749:89-97 pubmed publisher
  • western blot; human
Cen B, Xiong Y, Song J, Mahajan S, DuPont R, McEachern K, et al. The Pim-1 protein kinase is an important regulator of MET receptor tyrosine kinase levels and signaling. Mol Cell Biol. 2014;34:2517-32 pubmed publisher
Weng H, Huang H, Wu H, Qin X, Zhao B, Dong L, et al. METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification. Cell Stem Cell. 2018;22:191-205.e9 pubmed publisher
Sidrauski C, Tsai J, Kampmann M, Hearn B, Vedantham P, Jaishankar P, et al. Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response. elife. 2015;4:e07314 pubmed publisher
Spilka R, Laimer K, Bachmann F, Spizzo G, Vogetseder A, Wieser M, et al. Overexpression of eIF3a in Squamous Cell Carcinoma of the Oral Cavity and Its Putative Relation to Chemotherapy Response. J Oncol. 2012;2012:901956 pubmed publisher
product information
SKU :
3411S
Product-Name :
eIF3A (D51F4) XP® Rabbit mAb
Size :
100 ul
Price-(USD) :
260 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Translational Control
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
166
Host :
Rabbit
Target :
eIF3a
Primary-Protein :
eIF3-theta
Alt-Names :
EIF3,EIF3, p180 subunit,EIF3A,EIF3S10,Eukaryotic translation initiation factor 3 subunit 10,Eukaryotic translation initiation factor 3 subunit A,KIAA0139,P167,TIF32,centrosomin homolog,cytoplasmic protein p167,eIF-3-theta,eIF3 p167,eIF3 p180,eIF3 p185,eIF3-p170,eIF3-theta,eukaryotic translation initiation factor 3, subunit 10 (theta, 150/170kD),eukaryotic translation initiation factor 3, subunit 10 (theta, 170kD),eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa,eukaryotic translation initiation factor 3, subunit 10, 170kD,eukaryotic translation initiation factor 3, subunit A,p180,p185
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.