product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Cdc6 (C42F7) Rabbit mAb
catalog :
3387
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
C42F7
reactivity :
human, mouse, rat
application :
western blot
citations: 9
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 5a
Fischietti M, Eckerdt F, Blyth G, Arslan A, Mati W, Oku C, et al. Schlafen 5 as a novel therapeutic target in pancreatic ductal adenocarcinoma. Oncogene. 2021;40:3273-3286 pubmed publisher
  • western blot; human; loading ...; fig 1c, 1d
Karanika S, Karantanos T, Li L, Wang J, Park S, Yang G, et al. Targeting DNA Damage Response in Prostate Cancer by Inhibiting Androgen Receptor-CDC6-ATR-Chk1 Signaling. Cell Rep. 2017;18:1970-1981 pubmed publisher
  • western blot; human; loading ...; fig 1g
Shibata E, Kiran M, Shibata Y, Singh S, Kiran S, Dutta A. Two subunits of human ORC are dispensable for DNA replication and proliferation. elife. 2016;5: pubmed publisher
  • western blot; human; 1:1000
Shen Z, Stanger B. YAP regulates S-phase entry in endothelial cells. PLoS ONE. 2015;10:e0117522 pubmed publisher
  • western blot; human
Zhou P, Wang Z, Yuan X, Zhou C, Liu L, Wan X, et al. Mixed lineage leukemia 5 (MLL5) protein regulates cell cycle progression and E2F1-responsive gene expression via association with host cell factor-1 (HCF-1). J Biol Chem. 2013;288:17532-43 pubmed publisher
Mu Y, Zelazowska M, McBride K. Phosphorylation promotes activation-induced cytidine deaminase activity at the Myc oncogene. J Exp Med. 2017;214:3543-3552 pubmed publisher
Dogan T, Gnad F, Chan J, Phu L, Young A, Chen M, et al. Role of the E3 ubiquitin ligase RNF157 as a novel downstream effector linking PI3K and MAPK signaling pathways to the cell cycle. J Biol Chem. 2017;292:14311-14324 pubmed publisher
Schulz R, Streller F, Scheel A, Ruschoff J, Reinert M, Dobbelstein M, et al. HER2/ErbB2 activates HSF1 and thereby controls HSP90 clients including MIF in HER2-overexpressing breast cancer. Cell Death Dis. 2014;5:e980 pubmed publisher
Weyemi U, Lagente Chevallier O, Boufraqech M, Prenois F, Courtin F, Caillou B, et al. ROS-generating NADPH oxidase NOX4 is a critical mediator in oncogenic H-Ras-induced DNA damage and subsequent senescence. Oncogene. 2012;31:1117-29 pubmed publisher
product information
SKU :
3387S
Product-Name :
Cdc6 (C42F7) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Hm, Mk
Applications :
Western blot
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
62
Host :
Rabbit
Target :
CDC6
Primary-Protein :
Cdc6
Alt-Names :
CDC18 (cell division cycle 18, S.pombe, homolog)-like,CDC18L,CDC6,CDC6 cell division cycle 6 homolog,CDC6-related protein,Cdc18-related protein,Cell division control protein 6 homolog,HsCDC6,HsCdc18,cell division cycle 6 homolog (S. cerevisiae),cell division cycle 6 protein,p62(cdc6)
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.