product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
PCAF (C14G9) Rabbit mAb
catalog :
3378
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
C14G9
reactivity :
human, mouse, rat, cow
application :
western blot, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, RNA immunoprecipitation, other
citations: 13
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse; loading ...; fig 4e
  • western blot; mouse; loading ...; fig 4d
Bartolomé A, Zhu C, Sussel L, Pajvani U. Notch signaling dynamically regulates adult β cell proliferation and maturity. J Clin Invest. 2019;129:268-280 pubmed publisher
  • western blot; human; loading ...; fig 3a
Zhang Y, Cao Y, Zhang L, Feng C, Zhou G, Wen G. Apigenin inhibits C5a-induced proliferation of human nasopharyngeal carcinoma cells through down-regulation of C5aR. Biosci Rep. 2018;38: pubmed publisher
  • chromatin immunoprecipitation; human; loading ...; fig 5e
Lin Y, Lin Y, Huang M, Kuo P, Wu C, Lee M, et al. Tumor necrosis factor-alpha inhibitors suppress CCL2 chemokine in monocytes via epigenetic modification. Mol Immunol. 2017;83:82-91 pubmed publisher
  • western blot; human; 1:200; fig st1
Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  • immunoprecipitation; human; loading ...; fig 6a
  • western blot; human; loading ...; fig 6c
Zheng X, Xu M, Yao B, Wang C, Jia Y, Liu Q. IL-6/STAT3 axis initiated CAFs via up-regulating TIMP-1 which was attenuated by acetylation of STAT3 induced by PCAF in HCC microenvironment. Cell Signal. 2016;28:1314-24 pubmed publisher
  • RNA immunoprecipitation; human; fig 3
  • western blot; human; fig s3
G Hendrickson D, Kelley D, Tenen D, BERNSTEIN B, Rinn J. Widespread RNA binding by chromatin-associated proteins. Genome Biol. 2016;17:28 pubmed publisher
  • other; mouse; 1:500; fig s1
Chiang C, Uzoma I, Lane D, Memišević V, Alem F, Yao K, et al. A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection. Front Microbiol. 2015;6:683 pubmed publisher
  • western blot; human; fig 2
Montgomery D, Sorum A, Guasch L, Nicklaus M, Meier J. Metabolic Regulation of Histone Acetyltransferases by Endogenous Acyl-CoA Cofactors. Chem Biol. 2015;22:1030-1039 pubmed publisher
  • western blot; human; 1:1000; fig 1
Xu M, Nagati J, Xie J, Li J, Walters H, Moon Y, et al. An acetate switch regulates stress erythropoiesis. Nat Med. 2014;20:1018-26 pubmed publisher
  • chromatin immunoprecipitation; mouse
Kuwahara M, Suzuki J, Tofukuji S, Yamada T, Kanoh M, Matsumoto A, et al. The Menin-Bach2 axis is critical for regulating CD4 T-cell senescence and cytokine homeostasis. Nat Commun. 2014;5:3555 pubmed publisher
  • western blot; mouse
Ravnskjaer K, Hogan M, Lackey D, Tora L, Dent S, Olefsky J, et al. Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects. J Clin Invest. 2013;123:4318-28 pubmed publisher
  • western blot; rat
Bousiges O, Vasconcelos A, Neidl R, Cosquer B, Herbeaux K, Panteleeva I, et al. Spatial memory consolidation is associated with induction of several lysine-acetyltransferase (histone acetyltransferase) expression levels and H2B/H4 acetylation-dependent transcriptional events in the rat hippocampus. Neuropsychopharmacology. 2010;35:2521-37 pubmed publisher
Zhang G, Zhang W, Li B, Stringer Reasor E, Chu C, SUN L, et al. MicroRNA-200c and microRNA- 141 are regulated by a FOXP3-KAT2B axis and associated with tumor metastasis in breast cancer. Breast Cancer Res. 2017;19:73 pubmed publisher
product information
SKU :
3378S
Product-Name :
PCAF (C14G9) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk, (B, Hr)
Applications :
Chromatin Immunoprecipitation
Product-Category :
Chromatin Regulation / Nuclear Function
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
93
Host :
Rabbit
Target :
PCAF
Primary-Protein :
PCAF
Alt-Names :
CAF,CREBBP-associated factor,Histone acetylase PCAF,Histone acetyltransferase KAT2B,Histone acetyltransferase PCAF,K(lysine) acetyltransferase 2B,KAT2B,Lysine acetyltransferase 2B,P,P/CAF,P300/CBP-associated factor,PCAF
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.