product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Erk5 Antibody
catalog :
3372
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 9
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig s3c
Kennedy S, Jarboui M, Srihari S, Raso C, Bryan K, Dernayka L, et al. Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D. Nat Commun. 2020;11:499 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 2a
Giurisato E, Xu Q, Lonardi S, Telfer B, Russo I, Pearson A, et al. Myeloid ERK5 deficiency suppresses tumor growth by blocking protumor macrophage polarization via STAT3 inhibition. Proc Natl Acad Sci U S A. 2018;115:E2801-E2810 pubmed publisher
  • immunocytochemistry; human; fig 7
  • western blot; human; fig 1b
Wilkinson E, Sidaway J, Cross M. Statin regulated ERK5 stimulates tight junction formation and reduces permeability in human cardiac endothelial cells. J Cell Physiol. 2018;233:186-200 pubmed publisher
  • western blot; human; loading ...; fig 6d
Im J, Yoon S, Kim B, Ban H, Won K, Chung K, et al. DNA damage induced apoptosis suppressor (DDIAS) is upregulated via ERK5/MEF2B signaling and promotes ?-catenin-mediated invasion. Biochim Biophys Acta. 2016;1859:1449-1458 pubmed publisher
  • western blot; human; loading ...; fig 8c
Pereira D, Simões A, Gomes S, Castro R, Carvalho T, Rodrigues C, et al. MEK5/ERK5 signaling inhibition increases colon cancer cell sensitivity to 5-fluorouracil through a p53-dependent mechanism. Oncotarget. 2016;7:34322-40 pubmed publisher
Jo M, Chung A, Yachie N, Seo M, Jeon H, Nam Y, et al. Yeast genetic interaction screen of human genes associated with amyotrophic lateral sclerosis: identification of MAP2K5 kinase as a potential drug target. Genome Res. 2017;27:1487-1500 pubmed publisher
Namba Y, Togo S, Tulafu M, Kadoya K, Nagahama K, Taka H, et al. Combination of glycopyrronium and indacaterol inhibits carbachol-induced ERK5 signal in fibrotic processes. Respir Res. 2017;18:46 pubmed publisher
Granados Jaén A, Angulo Ibáñez M, Rovira Clavé X, Gamez C, Soriano F, Reina M, et al. Absence of ERK5/MAPK7 delays tumorigenesis in Atm-/- mice. Oncotarget. 2016;7:74435-74447 pubmed publisher
Lochhead P, Clark J, Wang L, Gilmour L, Squires M, Gilley R, et al. Tumor cells with KRAS or BRAF mutations or ERK5/MAPK7 amplification are not addicted to ERK5 activity for cell proliferation. Cell Cycle. 2016;15:506-18 pubmed publisher
product information
SKU :
3372S
Product-Name :
Erk5 Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunoprecipitation
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
115
Host :
Rabbit
Target :
ERK5
Primary-Protein :
ERK5
Alt-Names :
BMK-1,BMK1,BMK1 kinase,Big MAP kinase 1,ERK-5,ERK4,ERK5,Extracellular signal-regulated kinase 5,MAP kinase 7,MAPK 7,MAPK7,MK07,Mitogen-activated protein kinase 7,PRKM7,extracellular-signal-regulated kinase 5
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.