product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-Erk5 (Thr218/Tyr220) Antibody
catalog :
3371L
quantity :
300 ul
price :
658 USD
clonality :
polyclonal
host :
rabbit
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry
citations: 6
Published Application/Species/DilutionReference
  • western blot; human; fig 4
Gavine P, Wang M, Yu D, Hu E, Huang C, Xia J, et al. Identification and validation of dysregulated MAPK7 (ERK5) as a novel oncogenic target in squamous cell lung and esophageal carcinoma. BMC Cancer. 2015;15:454 pubmed publisher
  • western blot; human; fig 1
Simões A, Pereira D, Gomes S, Brito H, Carvalho T, French A, et al. Aberrant MEK5/ERK5 signalling contributes to human colon cancer progression via NF-κB activation. Cell Death Dis. 2015;6:e1718 pubmed publisher
  • western blot; human; 1:1000
  • immunohistochemistry; human
Zuo Y, Wu Y, Wehrli B, Chakrabarti S, Chakraborty C. Modulation of ERK5 is a novel mechanism by which Cdc42 regulates migration of breast cancer cells. J Cell Biochem. 2015;116:124-32 pubmed publisher
  • western blot; rat; 1:500
Su C, Sun F, Cunningham R, Rybalchenko N, Singh M. ERK5/KLF4 signaling as a common mediator of the neuroprotective effects of both nerve growth factor and hydrogen peroxide preconditioning. Age (Dordr). 2014;36:9685 pubmed publisher
  • western blot; human
Wang X, Pesakhov S, Harrison J, Danilenko M, Studzinski G. ERK5 pathway regulates transcription factors important for monocytic differentiation of human myeloid leukemia cells. J Cell Physiol. 2014;229:856-67 pubmed publisher
  • western blot; human; fig 1
  • western blot; mouse; fig 1
Takeda A, Oberoi-Khanuja T, Glatz G, Schulenburg K, Scholz R, Carpy A, et al. Ubiquitin-dependent regulation of MEKK2/3-MEK5-ERK5 signaling module by XIAP and cIAP1. EMBO J. 2014;33:1784-801 pubmed publisher
product information
SKU :
3371L
Product-Name :
Phospho-Erk5 (Thr218/Tyr220) Antibody
Size :
300 ul
Price-(USD) :
658 USD
Species-x-Reactivity :
H, M, R
Applications :
Western blot
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
115
Host :
Rabbit
Target :
ERK5 (Thr219/Tyr221) phosphate
Primary-Protein :
ERK5
Alt-Names :
BMK-1,BMK1,BMK1 kinase,Big MAP kinase 1,ERK-5,ERK4,ERK5,Extracellular signal-regulated kinase 5,MAP kinase 7,MAPK 7,MAPK7,MK07,Mitogen-activated protein kinase 7,PRKM7,extracellular-signal-regulated kinase 5
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.