product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Neuropilin-2 (D39A5) XP® Rabbit mAb
catalog :
3366
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D39A5
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - frozen section, western blot knockout validation
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; loading ...; fig 4c
  • western blot knockout validation; human; loading ...; fig 4g
Polavaram N, Dutta S, Islam R, Bag A, Roy S, Poitz D, et al. Tumor- and osteoclast-derived NRP2 in prostate cancer bone metastases. Bone Res. 2021;9:24 pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig 5a
Kalisch Smith J, Ved N, Szumska D, Munro J, Troup M, Harris S, et al. Maternal iron deficiency perturbs embryonic cardiovascular development in mice. Nat Commun. 2021;12:3447 pubmed publisher
  • immunohistochemistry; mouse; 1:500; fig 1
Hernández Enríquez B, Wu Z, Martinez E, Olsen O, Kaprielian Z, Maness P, et al. Floor plate-derived neuropilin-2 functions as a secreted semaphorin sink to facilitate commissural axon midline crossing. Genes Dev. 2015;29:2617-32 pubmed publisher
  • immunocytochemistry; mouse; fig s4
  • immunohistochemistry; mouse; loading ...; fig 1d
Kiermaier E, Moussion C, Veldkamp C, Gerardy Schahn R, de Vries I, Williams L, et al. Polysialylation controls dendritic cell trafficking by regulating chemokine recognition. Science. 2016;351:186-90 pubmed publisher
  • western blot; rat
Pellet Many C, Mehta V, Fields L, Mahmoud M, Lowe V, Evans I, et al. Neuropilins 1 and 2 mediate neointimal hyperplasia and re-endothelialization following arterial injury. Cardiovasc Res. 2015;108:288-98 pubmed publisher
  • western blot; mouse; fig 4
Eisner A, Pazyra Murphy M, Durresi E, Zhou P, Zhao X, Chadwick E, et al. The Eya1 phosphatase promotes Shh signaling during hindbrain development and oncogenesis. Dev Cell. 2015;33:22-35 pubmed publisher
Maimon R, Ionescu A, Bonnie A, Sweetat S, Wald Altman S, Inbar S, et al. miR126-5p Downregulation Facilitates Axon Degeneration and NMJ Disruption via a Non-Cell-Autonomous Mechanism in ALS. J Neurosci. 2018;38:5478-5494 pubmed publisher
Bollard J, Massoma P, Vercherat C, Blanc M, Lepinasse F, Gadot N, et al. The axon guidance molecule semaphorin 3F is a negative regulator of tumor progression and proliferation in ileal neuroendocrine tumors. Oncotarget. 2015;6:36731-45 pubmed publisher
Choi J, Ting C, Trogrlic L, Milevski S, Familari M, Martinez G, et al. A role for smoothened during murine lens and cornea development. PLoS ONE. 2014;9:e108037 pubmed publisher
Gutierrez Castellanos N, Pardo Bellver C, Martinez Garcia F, Lanuza E. The vomeronasal cortex - afferent and efferent projections of the posteromedial cortical nucleus of the amygdala in mice. Eur J Neurosci. 2014;39:141-58 pubmed publisher
Verlinden L, Kriebitzsch C, Beullens I, Tan B, Carmeliet G, Verstuyf A. Nrp2 deficiency leads to trabecular bone loss and is accompanied by enhanced osteoclast and reduced osteoblast numbers. Bone. 2013;55:465-75 pubmed publisher
Bielenberg D, Seth A, Shimizu A, Pelton K, Cristofaro V, Ramachandran A, et al. Increased smooth muscle contractility in mice deficient for neuropilin 2. Am J Pathol. 2012;181:548-59 pubmed publisher
Debrincat M, Josefsson E, James C, Henley K, Ellis S, Lebois M, et al. Mcl-1 and Bcl-x(L) coordinately regulate megakaryocyte survival. Blood. 2012;119:5850-8 pubmed publisher
product information
SKU :
3366S
Product-Name :
Neuropilin-2 (D39A5) XP® Rabbit mAb
Size :
100 ul
Price-(USD) :
260 USD
Species-x-Reactivity :
M, R
Applications :
Immunofluorescence (Frozen)
Product-Category :
Neuroscience
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
130
Host :
Rabbit
Target :
Neuropilin2
Primary-Protein :
NRP2
Alt-Names :
MGC126574,NP2,NPN2,NRP2,Neuropilin-2,PRO2714,VEGF165R2,Vascular endothelial cell growth factor 165 receptor 2,neuropilin 2,neuropilin-2a(17),neuropilin-2a(22),neuropilin-2b(0),receptor for VEGF165 and semaphorins class3,vascular endothelial growth factor-165 receptor 2
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.