product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Drosha (D28B1) Rabbit mAb
catalog :
3364P
quantity :
40 ul
price :
123 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human, mouse
application :
western blot, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 7
Published Application/Species/DilutionReference
  • western blot (knockdown validation); human; 1:1000; fig s1
Francia S, Cabrini M, Matti V, Oldani A, d'Adda di Fagagna F. DICER, DROSHA and DNA damage response RNAs are necessary for the secondary recruitment of DNA damage response factors. J Cell Sci. 2016;129:1468-76 pubmed publisher
  • western blot; mouse; 1:1000; fig 2
Murai K, Sun G, Ye P, Tian E, Yang S, Cui Q, et al. The TLX-miR-219 cascade regulates neural stem cell proliferation in neurodevelopment and schizophrenia iPSC model. Nat Commun. 2016;7:10965 pubmed publisher
  • western blot; human; 1:500; fig 3
Link S, Grund S, Diederichs S. Alternative splicing affects the subcellular localization of Drosha. Nucleic Acids Res. 2016;: pubmed
  • western blot; human; 1:1000
Mori M, Triboulet R, Mohseni M, Schlegelmilch K, Shrestha K, Camargo F, et al. Hippo signaling regulates microprocessor and links cell-density-dependent miRNA biogenesis to cancer. Cell. 2014;156:893-906 pubmed publisher
  • western blot; mouse; fig 5
Gurung B, Muhammad A, Hua X. Menin is required for optimal processing of the microRNA let-7a. J Biol Chem. 2014;289:9902-8 pubmed publisher
Smith J, Grey F, Uhrlaub J, Nikolich-Zugich J, Hirsch A. Induction of the cellular microRNA, Hs_154, by West Nile virus contributes to virus-mediated apoptosis through repression of antiapoptotic factors. J Virol. 2012;86:5278-87 pubmed publisher
Pickering B, Yu D, Van Dyke M. Nucleolin protein interacts with microprocessor complex to affect biogenesis of microRNAs 15a and 16. J Biol Chem. 2011;286:44095-103 pubmed publisher
product information
SKU :
3364P
Product-Name :
Drosha (D28B1) Rabbit mAb
Size :
40 ul
Price-(USD) :
123 USD
Species-x-Reactivity :
H, M
Applications :
Immunoprecipitation
Product-Category :
Translational Control
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
160
Host :
Rabbit
Target :
Drosha
Primary-Protein :
Drosha
Alt-Names :
Drosha,ETOHI2,HSA242976,RANSE3L,RN3,RNASE3L,RNASEN,RNC,RNase III,Ribonuclease 3,Ribonuclease III,drosha, double-stranded RNA-specific endoribonuclease,drosha, ribonuclease type III,nuclear RNase III Drosha,p241,putative protein p241 which interacts with transcription factor Sp1,putative ribonuclease III,ribonuclease III, nuclear,ribonuclease type III, nuclear
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.