product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
PI3 Kinase Class III (D4E2) Rabbit mAb
catalog :
3358
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
D4E2
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation
citations: 11
Published Application/Species/Sample/DilutionReference
  • western blot; rat; 1:1000; loading ...; fig 5f
Rong H, Zhao Z, Feng J, Lei Y, Wu H, Sun R, et al. The effects of dexmedetomidine pretreatment on the pro- and anti-inflammation systems after spinal cord injury in rats. Brain Behav Immun. 2017;64:195-207 pubmed publisher
  • western blot; human; loading ...; fig 1s1f
Jung J, Nayak A, Schaeffer V, Starzetz T, Kirsch A, Muller S, et al. Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator. elife. 2017;6: pubmed publisher
  • western blot; human; loading ...; fig 6a
Park J, Jung C, Seo M, Otto N, Grunwald D, Kim K, et al. The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14. Autophagy. 2016;12:547-64 pubmed publisher
  • immunocytochemistry; human; 1:500; fig 5
  • western blot; human; 1:500; fig 5
Button R, Vincent J, Strang C, Luo S. Dual PI-3 kinase/mTOR inhibition impairs autophagy flux and induces cell death independent of apoptosis and necroptosis. Oncotarget. 2016;7:5157-75 pubmed publisher
  • western blot; rat; 1:1000
Padiya R, Chowdhury D, Borkar R, Srinivas R, Pal Bhadra M, Banerjee S. Garlic attenuates cardiac oxidative stress via activation of PI3K/AKT/Nrf2-Keap1 pathway in fructose-fed diabetic rat. PLoS ONE. 2014;9:e94228 pubmed publisher
  • western blot; mouse; 1:500
Morabito M, Berman D, Schneider R, Zhang Y, Leibel R, Small S. Hyperleucinemia causes hippocampal retromer deficiency linking diabetes to Alzheimer's disease. Neurobiol Dis. 2014;65:188-92 pubmed publisher
  • western blot; human; 1:1000
Bauckman K, Haller E, Flores I, Nanjundan M. Iron modulates cell survival in a Ras- and MAPK-dependent manner in ovarian cells. Cell Death Dis. 2013;4:e592 pubmed publisher
Young C, Arteaga C, Cook R. Dual inhibition of Type I and Type III PI3 kinases increases tumor cell apoptosis in HER2+ breast cancers. Breast Cancer Res. 2015;17:148 pubmed publisher
Cui D, Wang L, Qi A, Zhou Q, Zhang X, Jiang W. Propofol prevents autophagic cell death following oxygen and glucose deprivation in PC12 cells and cerebral ischemia-reperfusion injury in rats. PLoS ONE. 2012;7:e35324 pubmed publisher
Yuan K, Lian Z, Sun B, Clayton M, Ng I, Feitelson M. Role of miR-148a in hepatitis B associated hepatocellular carcinoma. PLoS ONE. 2012;7:e35331 pubmed publisher
Siemens N, Patenge N, Otto J, Fiedler T, Kreikemeyer B. Streptococcus pyogenes M49 plasminogen/plasmin binding facilitates keratinocyte invasion via integrin-integrin-linked kinase (ILK) pathways and protects from macrophage killing. J Biol Chem. 2011;286:21612-22 pubmed publisher
product information
SKU :
3358S
Product-Name :
PI3 Kinase Class III (D4E2) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Western blot
Product-Category :
PI3K / Akt Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
100
Host :
Rabbit
Target :
PIK3C3
Primary-Protein :
PIK3C3
Alt-Names :
MGC61518,PI3-kinase type 3,PI3K type 3,PIK3C3,PK3C3,Phosphatidylinositol 3-kinase catalytic subunit type 3,Phosphatidylinositol 3-kinase p100 subunit,Phosphoinositide-3-kinase class 3,PtdIns-3-kinase type 3,VPS34,hVps34,phosphoinositide-3-kinase, class 3
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.