product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-ALK (Tyr1604) Antibody
catalog :
3341S
quantity :
100 ul
price :
274 USD
clonality :
polyclonal
host :
rabbit
antigen modification :
phosphorylated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 8
Published Application/Species/DilutionReference
  • western blot; human; fig 1
Debruyne D, Bhatnagar N, Sharma B, Luther W, Moore N, Cheung N, et al. ALK inhibitor resistance in ALK(F1174L)-driven neuroblastoma is associated with AXL activation and induction of EMT. Oncogene. 2016;35:3681-91 pubmed publisher
  • western blot; human; fig 4
Ardini E, Menichincheri M, Banfi P, Bosotti R, De Ponti C, Pulci R, et al. Entrectinib, a Pan-TRK, ROS1, and ALK Inhibitor with Activity in Multiple Molecularly Defined Cancer Indications. Mol Cancer Ther. 2016;15:628-39 pubmed publisher
  • immunohistochemistry; human; fig 1
  • immunocytochemistry; human; fig 1
  • western blot; human; fig 1
Ceccon M, Merlo M, Mologni L, Poggio T, Varesio L, Menotti M, et al. Excess of NPM-ALK oncogenic signaling promotes cellular apoptosis and drug dependency. Oncogene. 2015;: pubmed publisher
  • western blot; mouse
Kodama T, Tsukaguchi T, Yoshida M, Kondoh O, Sakamoto H. Selective ALK inhibitor alectinib with potent antitumor activity in models of crizotinib resistance. Cancer Lett. 2014;351:215-21 pubmed publisher
  • western blot; human
George S, Vishwamitra D, Manshouri R, Shi P, Amin H. The ALK inhibitor ASP3026 eradicates NPM-ALK⁺ T-cell anaplastic large-cell lymphoma in vitro and in a systemic xenograft lymphoma model. Oncotarget. 2014;5:5750-63 pubmed
  • western blot; human; 1:1000
  • western blot; mouse; 1:1000
Kishida S, Mu P, Miyakawa S, Fujiwara M, Abe T, Sakamoto K, et al. Midkine promotes neuroblastoma through Notch2 signaling. Cancer Res. 2013;73:1318-27 pubmed publisher
Desjobert C, Renalier M, Bergalet J, Dejean E, Joseph N, Kruczynski A, et al. MiR-29a down-regulation in ALK-positive anaplastic large cell lymphomas contributes to apoptosis blockade through MCL-1 overexpression. Blood. 2011;117:6627-37 pubmed publisher
Mosse Y, Laudenslager M, Longo L, Cole K, Wood A, Attiyeh E, et al. Identification of ALK as a major familial neuroblastoma predisposition gene. Nature. 2008;455:930-5 pubmed publisher
product information
SKU :
3341S
Product-Name :
Phospho-ALK (Tyr1604) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H
Applications :
Immunoprecipitation
Product-Category :
RTK
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
80 (NPM-ALK) 220 (ALK)
Host :
Rabbit
Target :
ALK (Tyr1604) phosphate
Primary-Protein :
ALK
Alt-Names :
ALK,ALK tyrosine kinase receptor,Anaplastic lymphoma kinase,CD246,CD246 antigen,NBLST3,TFG/ALK,anaplastic lymphoma receptor tyrosine kinase
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.