product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
ALK (C26G7) Rabbit mAb
catalog :
3333S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human, mouse
application :
western blot, immunoprecipitation
citations: 6
Published Application/Species/DilutionReference
  • western blot; human; fig 1
Debruyne D, Bhatnagar N, Sharma B, Luther W, Moore N, Cheung N, et al. ALK inhibitor resistance in ALK(F1174L)-driven neuroblastoma is associated with AXL activation and induction of EMT. Oncogene. 2016;35:3681-91 pubmed publisher
  • western blot; human; fig 6
Papadakis A, Sun C, Knijnenburg T, Xue Y, Grernrum W, Hölzel M, et al. SMARCE1 suppresses EGFR expression and controls responses to MET and ALK inhibitors in lung cancer. Cell Res. 2015;25:445-58 pubmed publisher
  • western blot; human; 1:1000
Davare M, Vellore N, Wagner J, Eide C, Goodman J, Drilon A, et al. Structural insight into selectivity and resistance profiles of ROS1 tyrosine kinase inhibitors. Proc Natl Acad Sci U S A. 2015;112:E5381-90 pubmed publisher
  • western blot; human; 1:1000
  • western blot; mouse; 1:1000
Kishida S, Mu P, Miyakawa S, Fujiwara M, Abe T, Sakamoto K, et al. Midkine promotes neuroblastoma through Notch2 signaling. Cancer Res. 2013;73:1318-27 pubmed publisher
Stutz E, Gautschi O, Fey M, Gugger M, Tschan M, Rothschild S. Crizotinib inhibits migration and expression of ID1 in MET-positive lung cancer cells: implications for MET targeting in oncology. Future Oncol. 2014;10:211-7 pubmed publisher
Mosse Y, Laudenslager M, Longo L, Cole K, Wood A, Attiyeh E, et al. Identification of ALK as a major familial neuroblastoma predisposition gene. Nature. 2008;455:930-5 pubmed publisher
product information
SKU :
3333S
Product-Name :
ALK (C26G7) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H
Applications :
Immunoprecipitation
Product-Category :
RTK
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
80 (NPM-ALK), 220 (ALK)
Host :
Rabbit
Target :
ALK
Primary-Protein :
ALK
Alt-Names :
ALK,ALK tyrosine kinase receptor,Anaplastic lymphoma kinase,CD246,CD246 antigen,NBLST3,TFG/ALK,anaplastic lymphoma receptor tyrosine kinase
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.