Phospho-Jak1 (Tyr1022/1023) Antibody | Cell Signaling Technology 3331 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Phospho-Jak1 (Tyr1022/1023) Antibody

catalog :

3331

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human, mouse, rat, bovine

application :

western blot, immunohistochemistry

more info or order :

Cell Signaling Technology product webpage

citations: 15

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 5a, s7d western blot; mouse; loading ...; fig s7c	He Y, Luo W, Liu Y, Wang Y, Ma C, Wu Q, et al. IL-20RB mediates tumoral response to osteoclastic niches and promotes bone metastasis of lung cancer. J Clin Invest. 2022;132: pubmed publisher
western blot; human; loading ...; fig 1f	Han J, Chen X, Xu J, Chu L, Li R, Sun N, et al. Simultaneous silencing Aurora-A and UHRF1 inhibits colorectal cancer cell growth through regulating expression of DNMT1 and STAT1. Int J Med Sci. 2021;18:3437-3451 pubmed publisher
western blot; human; 1:1000; loading ...; fig 3g, 3i western blot; mouse; 1:1000; fig 3h	Xu P, Xiong W, Lin Y, Fan L, Pan H, Li Y. Histone deacetylase 2 knockout suppresses immune escape of triple-negative breast cancer cells via downregulating PD-L1 expression. Cell Death Dis. 2021;12:779 pubmed publisher
western blot; mouse; loading ...; fig 1c	Wang E, Dai Z, Ferrante A, Drake C, Christiano A. A Subset of TREM2+ Dermal Macrophages Secretes Oncostatin M to Maintain Hair Follicle Stem Cell Quiescence and Inhibit Hair Growth. Cell Stem Cell. 2019;: pubmed publisher
western blot; mouse; loading ...; fig 3d	Biffi G, Oni T, Spielman B, Hao Y, Elyada E, Park Y, et al. IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma. Cancer Discov. 2019;9:282-301 pubmed publisher
western blot; mouse; loading ...; fig 1f	Xu X, Xu J, Wu J, Hu Y, Han Y, Gu Y, et al. Phosphorylation-Mediated IFN-γR2 Membrane Translocation Is Required to Activate Macrophage Innate Response. Cell. 2018;175:1336-1351.e17 pubmed publisher
western blot; human; loading ...; fig 9a	Patel S, Sanjana N, Kishton R, Eidizadeh A, Vodnala S, Cam M, et al. Identification of essential genes for cancer immunotherapy. Nature. 2017;548:537-542 pubmed publisher
western blot; human; 1:1000; loading ...; fig 3a	Eletto D, Burns S, Angulo I, Plagnol V, Gilmour K, Henriquez F, et al. Biallelic JAK1 mutations in immunodeficient patient with mycobacterial infection. Nat Commun. 2016;7:13992 pubmed publisher
western blot; human; loading ...; fig 5a	Li Y, Buijs Gladdines J, Cant Barrett K, Stubbs A, Vroegindeweij E, Smits W, et al. IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing Study. PLoS Med. 2016;13:e1002200 pubmed publisher
western blot; mouse; loading ...; fig s8	Ganta V, Choi M, Kutateladze A, Annex B. VEGF165b Modulates Endothelial VEGFR1-STAT3 Signaling Pathway and Angiogenesis in Human and Experimental Peripheral Arterial Disease. Circ Res. 2017;120:282-295 pubmed publisher
western blot; mouse; loading ...; fig 4	Ramratnam M, Salama G, Sharma R, Wang D, Smith S, Banerjee S, et al. Gene-Targeted Mice with the Human Troponin T R141W Mutation Develop Dilated Cardiomyopathy with Calcium Desensitization. PLoS ONE. 2016;11:e0167681 pubmed publisher
western blot; human; 1:200; loading ...; fig s4	Bonan S, Albrengues J, Grasset E, Kuzet S, Nottet N, Bourget I, et al. Membrane-bound ICAM-1 contributes to the onset of proinvasive tumor stroma by controlling acto-myosin contractility in carcinoma-associated fibroblasts. Oncotarget. 2017;8:1304-1320 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 9a	He Y, Yan Y, Zhang H, Lin Y, Chen Y, Yan Y, et al. Methyl salicylate 2-O-?-d-lactoside alleviates the pathological progression of pristane-induced systemic lupus erythematosus-like disease in mice via suppression of inflammatory response and signal transduction. Drug Des Devel Ther. 2016;10:3183-3196 pubmed
western blot; human; loading ...; fig 3f immunohistochemistry; mouse; loading ...; fig 3g	Yasuda T, Fukada T, Nishida K, Nakayama M, Matsuda M, Miura I, et al. Hyperactivation of JAK1 tyrosine kinase induces stepwise, progressive pruritic dermatitis. J Clin Invest. 2016;126:2064-76 pubmed publisher
	Cant Barrett K, Spijkers Hagelstein J, Buijs Gladdines J, Uitdehaag J, Smits W, van der Zwet J, et al. MEK and PI3K-AKT inhibitors synergistically block activated IL7 receptor signaling in T-cell acute lymphoblastic leukemia. Leukemia. 2016;30:1832-43 pubmed publisher

product information

SKU :

3331S

Product-Name :

Phospho-Jak1 (Tyr1022/1023) Antibody

Size :

100 ul

Price-(USD) :

274 USD

Species-x-Reactivity :

H, M, (R, B)

Applications :

Western blot

Product-Category :

Immunology and Inflammation

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Polyclonal Antibody

MW :

130

Host :

Rabbit

Target :

JAK1 (Tyr1034/Tyr1035) phosphate

Primary-Protein :

JAK1

Alt-Names :

JAK-1,JAK1,JAK1A,JAK1B,JTK3,Janus kinase 1,Janus kinase 1 (a protein tyrosine kinase),Tyrosine-protein kinase JAK1

more info or order :

Cell Signaling Technology product webpage