product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-Cofilin (Ser3) (77G2) Rabbit mAb
catalog :
3313S
quantity :
100 ul
price :
274 USD
clonality :
monoclonal
host :
rabbit
antigen modification :
phosphorylated
reactivity :
human, mouse, rat, cow
application :
western blot, immunocytochemistry, other
citations: 16
Published Application/Species/DilutionReference
  • western blot; human; 1:1000; fig st1
Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  • western blot; human; fig 2
Kourtidis A, Anastasiadis P. PLEKHA7 defines an apical junctional complex with cytoskeletal associations and miRNA-mediated growth implications. Cell Cycle. 2016;15:498-505 pubmed publisher
  • western blot; human; fig 7
Hall A, Lu W, Godfrey J, Antonov A, Paicu C, Moxon S, et al. The cytoskeleton adaptor protein ankyrin-1 is upregulated by p53 following DNA damage and alters cell migration. Cell Death Dis. 2016;7:e2184 pubmed publisher
  • western blot; mouse; 1:1000; fig s4
Chang K, Nayak R, Roy S, Perumbeti A, Wellendorf A, Bezold K, et al. Vasculopathy-associated hyperangiotensinemia mobilizes haematopoietic stem cells/progenitors through endothelial AT₂R and cytoskeletal dysregulation. Nat Commun. 2015;6:5914 pubmed publisher
  • western blot; human; fig s2
Hong N, Qi A, Weaver A. PI(3,5)P2 controls endosomal branched actin dynamics by regulating cortactin-actin interactions. J Cell Biol. 2015;210:753-69 pubmed publisher
  • western blot; human
Vaškovičová K, Szabadosová E, Cermák V, Gandalovičová A, Kasalová L, Rosel D, et al. PKCα promotes the mesenchymal to amoeboid transition and increases cancer cell invasiveness. BMC Cancer. 2015;15:326 pubmed publisher
  • western blot; human; 1:500; fig 7
Li G, Zhou J, Budhraja A, Hu X, Chen Y, Cheng Q, et al. Mitochondrial translocation and interaction of cofilin and Drp1 are required for erucin-induced mitochondrial fission and apoptosis. Oncotarget. 2015;6:1834-49 pubmed
  • other; mouse; 1:1000; fig s1
Chiang C, Uzoma I, Lane D, Memisevic V, Alem F, Yao K, et al. A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection. Front Microbiol. 2015;6:683 pubmed publisher
  • immunocytochemistry; human
Kalendová A, Kalasová I, Yamazaki S, Uličná L, Harata M, Hozak P. Nuclear actin filaments recruit cofilin and actin-related protein 3, and their formation is connected with a mitotic block. Histochem Cell Biol. 2014;142:139-52 pubmed publisher
  • western blot; mouse; 1:1000
Georgess D, Mazzorana M, Terrado J, Delprat C, Chamot C, Guasch R, et al. Comparative transcriptomics reveals RhoE as a novel regulator of actin dynamics in bone-resorbing osteoclasts. Mol Biol Cell. 2014;25:380-96 pubmed publisher
  • western blot; human; 1:500
Valtcheva N, Primorac A, Jurisic G, Hollmen M, Detmar M. The orphan adhesion G protein-coupled receptor GPR97 regulates migration of lymphatic endothelial cells via the small GTPases RhoA and Cdc42. J Biol Chem. 2013;288:35736-48 pubmed publisher
Kwok W, Clemens M. Rho-kinase activation contributes to Lps-induced impairment of endothelial nitric oxide synthase activation by endothelin-1 in cultured hepatic sinusoidal endothelial cells. Shock. 2014;42:554-61 pubmed publisher
Ho H, Soto Hopkin A, Kapadia R, Vasudeva P, Schilling J, Ganesan A. RhoJ modulates melanoma invasion by altering actin cytoskeletal dynamics. Pigment Cell Melanoma Res. 2013;26:218-25 pubmed publisher
Tang X, Jin R, Qu G, Wang X, Li Z, Yuan Z, et al. GPR116, an adhesion G-protein-coupled receptor, promotes breast cancer metastasis via the Gαq-p63RhoGEF-Rho GTPase pathway. Cancer Res. 2013;73:6206-18 pubmed publisher
Xiang Y, Zheng K, Ju H, Wang S, Pei Y, Ding W, et al. Cofilin 1-mediated biphasic F-actin dynamics of neuronal cells affect herpes simplex virus 1 infection and replication. J Virol. 2012;86:8440-51 pubmed publisher
Negash S, Narasimhan S, Zhou W, Liu J, Wei F, Tian J, et al. Role of cGMP-dependent protein kinase in regulation of pulmonary vascular smooth muscle cell adhesion and migration: effect of hypoxia. Am J Physiol Heart Circ Physiol. 2009;297:H304-12 pubmed publisher
product information
SKU :
3313S
Product-Name :
Phospho-Cofilin (Ser3) (77G2) Rabbit mAb
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R, Mk, B
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Cytoskeletal Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
19
Host :
Rabbit
Target :
cofilin 1 (Ser3) phosphate
Primary-Protein :
cofilin 1
Alt-Names :
18 kDa phosphoprotein,CFL,CFL1,COF1,Cofilin, non-muscle isoform,Cofilin-1,cofilin 1 (non-muscle),p18
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.