| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot knockout validation; mouse; loading ...; fig 6c
| Ge J, Burnier L, Adamopoulou M, Kwa M, Schaks M, Rottner K, et al. RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells. J Biol Chem. 2018;293:9358-9369 pubmed publisher |
- western blot; human; loading ...; fig s2f
| Georgouli M, Herraiz C, Crosas Molist E, Fanshawe B, Maiques O, Perdrix A, et al. Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment. Cell. 2019;176:757-774.e23 pubmed publisher |
- western blot; human; loading ...; fig 4d
| Rondon A, de Almeida V, Gomes T, Verçoza B, Carvalho R, Konig S, et al. Tissue factor mediates microvesicles shedding from MDA-MB-231 breast cancer cells. Biochem Biophys Res Commun. 2018;502:137-144 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 5e
| Chiang A, Fowler S, Savjani R, Hilsenbeck S, Wallace C, Cirrito J, et al. Combination anti-Aβ treatment maximizes cognitive recovery and rebalances mTOR signaling in APP mice. J Exp Med. 2018;215:1349-1364 pubmed publisher |
- western blot; mouse; loading ...; fig 9a
| Pleines I, Woods J, Chappaz S, Kew V, Foad N, Ballester Beltrán J, et al. Mutations in tropomyosin 4 underlie a rare form of human macrothrombocytopenia. J Clin Invest. 2017;127:814-829 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 9a
| Zimprich A, Mroz G, Meyer Zu Reckendorf C, Anastasiadou S, Förstner P, Garrett L, et al. Serum Response Factor (SRF) Ablation Interferes with Acute Stress-Associated Immediate and Long-Term Coping Mechanisms. Mol Neurobiol. 2017;54:8242-8262 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 3a
| Sivadasan R, Hornburg D, Drepper C, Frank N, Jablonka S, Hansel A, et al. C9ORF72 interaction with cofilin modulates actin dynamics in motor neurons. Nat Neurosci. 2016;19:1610-1618 pubmed publisher |
- western blot; human; fig 2
| Segatto I, Massarut S, Boyle R, Baldassarre G, Walker D, Belletti B. Preclinical validation of a novel compound targeting p70S6 kinase in breast cancer. Aging (Albany NY). 2016;8:958-76 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig s4
| Anastasiadou S, Knöll B. The multiple sclerosis drug fingolimod (FTY720) stimulates neuronal gene expression, axonal growth and regeneration. Exp Neurol. 2016;279:243-260 pubmed publisher |
- western blot; human; fig 7
| Giehl K, Keller C, Muehlich S, Goppelt Struebe M. Actin-mediated gene expression depends on RhoA and Rac1 signaling in proximal tubular epithelial cells. PLoS ONE. 2015;10:e0121589 pubmed publisher |
- western blot; mouse; 1:1000; fig s10
| Arbeille E, Reynaud F, Sanyas I, Bozon M, Kindbeiter K, Causeret F, et al. Cerebrospinal fluid-derived Semaphorin3B orients neuroepithelial cell divisions in the apicobasal axis. Nat Commun. 2015;6:6366 pubmed publisher |
| Ito T, Taniguchi H, Fukagai K, Okamuro S, Kobayashi A. Inhibitory mechanism of FAT4 gene expression in response to actin dynamics during Src-induced carcinogenesis. PLoS ONE. 2015;10:e0118336 pubmed publisher |
- immunohistochemistry; human; fig 1
- western blot; human; fig 5
| Mardilovich K, Gabrielsen M, McGarry L, Orange C, Patel R, Shanks E, et al. Elevated LIM kinase 1 in nonmetastatic prostate cancer reflects its role in facilitating androgen receptor nuclear translocation. Mol Cancer Ther. 2015;14:246-58 pubmed publisher |
- western blot; mouse; 1:500
| Fowler S, Chiang A, Savjani R, Larson M, Sherman M, Schuler D, et al. Genetic modulation of soluble A? rescues cognitive and synaptic impairment in a mouse model of Alzheimer's disease. J Neurosci. 2014;34:7871-85 pubmed publisher |
| Wang H, Lewsadder M, Dorn E, Xu S, Lakshmana M. RanBP9 overexpression reduces dendritic arbor and spine density. Neuroscience. 2014;265:253-62 pubmed publisher |
| Shi J, Wu X, Surma M, Vemula S, Zhang L, Yang Y, et al. Distinct roles for ROCK1 and ROCK2 in the regulation of cell detachment. Cell Death Dis. 2013;4:e483 pubmed publisher |
| Maheswaranathan M, Gole H, Fernandez I, LASSEGUE B, Griendling K, San Martin A. Platelet-derived growth factor (PDGF) regulates Slingshot phosphatase activity via Nox1-dependent auto-dephosphorylation of serine 834 in vascular smooth muscle cells. J Biol Chem. 2011;286:35430-7 pubmed publisher |
| Kempf S, Janik D, Barjaktarovic Z, Braga Tanaka I, Tanaka S, Neff F, et al. Chronic low-dose-rate ionising radiation affects the hippocampal phosphoproteome in the ApoE-/- Alzheimer's mouse model. Oncotarget. 2016;7:71817-71832 pubmed publisher |
| Sigloch F, Burk U, Biniossek M, Brabletz T, Schilling O. miR-200c dampens cancer cell migration via regulation of protein kinase A subunits. Oncotarget. 2015;6:23874-89 pubmed |
| Kempf S, Casciati A, Buratovic S, Janik D, von Toerne C, Ueffing M, et al. The cognitive defects of neonatally irradiated mice are accompanied by changed synaptic plasticity, adult neurogenesis and neuroinflammation. Mol Neurodegener. 2014;9:57 pubmed publisher |
| Surma M, Handy C, Chang J, Kapur R, Wei L, Shi J. ROCK1 deficiency enhances protective effects of antioxidants against apoptosis and cell detachment. PLoS ONE. 2014;9:e90758 pubmed publisher |
| Schulte B, John I, Simon B, Brockmann C, Oelmeier S, Jahraus B, et al. A reducing milieu renders cofilin insensitive to phosphatidylinositol 4,5-bisphosphate (PIP2) inhibition. J Biol Chem. 2013;288:29430-9 pubmed publisher |
| Gamell C, Schofield A, Suryadinata R, Sarcevic B, Bernard O. LIMK2 mediates resistance to chemotherapeutic drugs in neuroblastoma cells through regulation of drug-induced cell cycle arrest. PLoS ONE. 2013;8:e72850 pubmed publisher |
| Li R, Doherty J, Antonipillai J, Chen S, Devlin M, Visser K, et al. LIM kinase inhibition reduces breast cancer growth and invasiveness but systemic inhibition does not reduce metastasis in mice. Clin Exp Metastasis. 2013;30:483-95 pubmed publisher |
| Taulet N, Delorme Walker V, DerMardirossian C. Reactive oxygen species regulate protrusion efficiency by controlling actin dynamics. PLoS ONE. 2012;7:e41342 pubmed publisher |
| Thirone A, Speight P, Zulys M, Rotstein O, Szaszi K, Pedersen S, et al. Hyperosmotic stress induces Rho/Rho kinase/LIM kinase-mediated cofilin phosphorylation in tubular cells: key role in the osmotically triggered F-actin response. Am J Physiol Cell Physiol. 2009;296:C463-75 pubmed publisher |
