product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
G9a/EHMT2 (C6H3) Rabbit mAb
catalog :
3306S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human, mouse, rat, cow, zebrafish
application :
western blot, immunocytochemistry, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 15
Published Application/Species/DilutionReference
  • western blot (knockdown validation); mouse; fig 1
  • western blot; human; fig 3
Ow J, Palanichamy Kala M, Rao V, Choi M, Bharathy N, Taneja R. G9a inhibits MEF2C activity to control sarcomere assembly. Sci Rep. 2016;6:34163 pubmed publisher
  • western blot (knockdown validation); zebrafish; fig 1
Olsen J, Wong L, Deimling S, Miles A, Guo H, Li Y, et al. G9a and ZNF644 Physically Associate to Suppress Progenitor Gene Expression during Neurogenesis. Stem Cell Reports. 2016;7:454-70 pubmed publisher
  • western blot (knockdown validation); mouse; fig 1
  • immunoprecipitation; mouse; fig 6
  • immunocytochemistry; mouse; fig 6
Rao V, Ow J, Shankar S, Bharathy N, Manikandan J, Wang Y, et al. G9a promotes proliferation and inhibits cell cycle exit during myogenic differentiation. Nucleic Acids Res. 2016;44:8129-43 pubmed publisher
  • western blot (knockdown validation); human; fig 2
  • immunoprecipitation; human; fig 2
Lee J, Lee S, Heo S, Kim K, Kim C, Kim D, et al. Novel Function of Lysine Methyltransferase G9a in the Regulation of Sox2 Protein Stability. PLoS ONE. 2015;10:e0141118 pubmed publisher
  • western blot (knockdown validation); human; fig 3
Hsiao S, Chen M, Chen C, Chien M, Hua K, Hsiao M, et al. The H3K9 Methyltransferase G9a Represses E-cadherin and is Associated with Myometrial Invasion in Endometrial Cancer. Ann Surg Oncol. 2015;22:1556-65 pubmed publisher
  • western blot; human
Duvall-Noelle N, Karwandyar A, Richmond A, Raman D. LASP-1: a nuclear hub for the UHRF1-DNMT1-G9a-Snail1 complex. Oncogene. 2016;35:1122-33 pubmed publisher
  • immunocytochemistry; human; 1:200
  • western blot; human; 1:1000
Ren A, Qiu Y, Cui H, Fu G. Inhibition of H3K9 methyltransferase G9a induces autophagy and apoptosis in oral squamous cell carcinoma. Biochem Biophys Res Commun. 2015;459:10-7 pubmed publisher
  • western blot; rat; 1:500; fig 2
Liu J, Magri L, Zhang F, Marsh N, Albrecht S, Huynh J, et al. Chromatin landscape defined by repressive histone methylation during oligodendrocyte differentiation. J Neurosci. 2015;35:352-65 pubmed publisher
  • western blot; mouse; 1:1000
Subbanna S, Nagre N, Shivakumar M, Umapathy N, Psychoyos D, Basavarajappa B. Ethanol induced acetylation of histone at G9a exon1 and G9a-mediated histone H3 dimethylation leads to neurodegeneration in neonatal mice. Neuroscience. 2014;258:422-32 pubmed publisher
  • immunocytochemistry; mouse
Hattangadi S, Martinez-Morilla S, Patterson H, Shi J, Burke K, Avila-Figueroa A, et al. Histones to the cytosol: exportin 7 is essential for normal terminal erythroid nuclear maturation. Blood. 2014;124:1931-40 pubmed
  • western blot; mouse; 1:1000
Jefferson W, Chevalier D, Phelps J, Cantor A, Padilla-Banks E, Newbold R, et al. Persistently altered epigenetic marks in the mouse uterus after neonatal estrogen exposure. Mol Endocrinol. 2013;27:1666-77 pubmed publisher
  • western blot; mouse; 1:1000
Subbanna S, Shivakumar M, Umapathy N, Saito M, Mohan P, Kumar A, et al. G9a-mediated histone methylation regulates ethanol-induced neurodegeneration in the neonatal mouse brain. Neurobiol Dis. 2013;54:475-85 pubmed publisher
Ma X, Chao S, Huang X, Lin F, Qin L, Wang X, et al. The Dynamics and Regulatory Mechanism of Pronuclear H3k9me2 Asymmetry in Mouse Zygotes. Sci Rep. 2015;5:17924 pubmed publisher
Lehnertz B, Pabst C, Su L, Miller M, Liu F, Yi L, et al. The methyltransferase G9a regulates HoxA9-dependent transcription in AML. Genes Dev. 2014;28:317-27 pubmed publisher
Lee M, Kuo Y, Chou W, Hou H, Hsiao M, Tien H. Gfi-1 is the transcriptional repressor of SOCS1 in acute myeloid leukemia cells. J Leukoc Biol. 2014;95:105-15 pubmed publisher
product information
SKU :
3306S
Product-Name :
G9a/EHMT2 (C6H3) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk, (B, Pg, Hr)
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Chromatin Regulation / Nuclear Function
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
140, 165
Host :
Rabbit
Target :
EHMT2
Primary-Protein :
EHMT2
Alt-Names :
BAT8,C6orf30,DKFZp686H08213,EHMT2,Euchromatic histone-lysine N-methyltransferase 2,FLJ35547,G9A,G9A histone methyltransferase,H3-K9-HMTase 3,HLA-B associated transcript 8,HLA-B-associated transcript 8,Histone H3-K9 methyltransferase 3,Histone-lysine N-methyltransferase, H3 lysine-9 specific 3,KMT1C,Lysine N-methyltransferase 1C,NG36,Protein G9a,ankyrin repeat-containing protein
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.