| Published Application/Species/Dilution | Reference |
|---|
- western blot (knockdown validation); mouse; fig 2C
| Wang Z, Liu N, Liu K, Zhou G, Gan J, Wang Z, et al. Autophagy mediated CoCrMo particle-induced peri-implant osteolysis by promoting osteoblast apoptosis. Autophagy. 2015;11:2358-69 pubmed publisher |
- western blot; mouse; 1:1000; fig 4b
| Xu Z, Bu Y, Chitnis N, Koumenis C, Fuchs S, Diehl J. miR-216b regulation of c-Jun mediates GADD153/CHOP-dependent apoptosis. Nat Commun. 2016;7:11422 pubmed publisher |
- western blot; mouse; 1:1000; fig 2
| Liu J, Ma Y, Sun C, Li S, Wang J. High Mobility Group Box1 Protein Is Involved in Endoplasmic Reticulum Stress Induced by Clostridium difficile Toxin A. Biomed Res Int. 2016;2016:4130834 pubmed publisher |
| Krokowski D, Jobava R, Guan B, Farabaugh K, Wu J, Majumder M, et al. Coordinated Regulation of the Neutral Amino Acid Transporter SNAT2 and the Protein Phosphatase Subunit GADD34 Promotes Adaptation to Increased Extracellular Osmolarity. J Biol Chem. 2015;290:17822-37 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; fig 5
- immunocytochemistry; human; fig s2
- immunoprecipitation; human; fig 3
- western blot; human; 1:2000; fig 1
- western blot; mouse; 1:2000; fig 1
| Sun S, Shi G, Sha H, Ji Y, Han X, Shu X, et al. IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation. Nat Cell Biol. 2015;17:1546-55 pubmed publisher |
| D'Osualdo A, Anania V, Yu K, Lill J, Kaufman R, Matsuzawa S, et al. Transcription Factor ATF4 Induces NLRP1 Inflammasome Expression during Endoplasmic Reticulum Stress. PLoS ONE. 2015;10:e0130635 pubmed publisher |
| Bejaoui M, Pantazi E, De Luca V, Panisello A, Folch-Puy E, Hotter G, et al. Carbonic Anhydrase Protects Fatty Liver Grafts against Ischemic Reperfusion Damage. PLoS ONE. 2015;10:e0134499 pubmed publisher |
- western blot; human; fig 5
| Cui J, Sun W, Hao X, Wei M, Su X, Zhang Y, et al. EHMT2 inhibitor BIX-01294 induces apoptosis through PMAIP1-USP9X-MCL1 axis in human bladder cancer cells. Cancer Cell Int. 2015;15:4 pubmed publisher |
- western blot; human; fig 1
| Hotokezaka Y, Katayama I, van Leyen K, Nakamura T. GSK-3β-dependent downregulation of γ-taxilin and αNAC merge to regulate ER stress responses. Cell Death Dis. 2015;6:e1719 pubmed publisher |
- western blot; human; fig 1,2,3,5,6,7
- western blot; mouse; fig 1,2,4,7
| So J, Cho S, Min S, Kimball S, Lee A. IRE1α-Dependent Decay of CReP/Ppp1r15b mRNA Increases Eukaryotic Initiation Factor 2α Phosphorylation and Suppresses Protein Synthesis. Mol Cell Biol. 2015;35:2761-70 pubmed publisher |
- western blot; human; fig 2
| Sheng X, Arnoldussen Y, Storm M, Tesikova M, Nenseth H, Zhao S, et al. Divergent androgen regulation of unfolded protein response pathways drives prostate cancer. EMBO Mol Med. 2015;7:788-801 pubmed publisher |
- immunoprecipitation; human; fig 1
| Plumb R, Zhang Z, Appathurai S, Mariappan M. A functional link between the co-translational protein translocation pathway and the UPR. elife. 2015;4: pubmed publisher |
- western blot; human; 1:1000
| Le Pape S, Dimitrova E, Hannaert P, Konovalov A, Volmer R, Ron D, et al. Polynomial algebra reveals diverging roles of the unfolded protein response in endothelial cells during ischemia-reperfusion injury. FEBS Lett. 2014;588:3062-7 pubmed publisher |
| Zhuo X, Wu Y, Ni Y, Liu J, Gong M, Wang X, et al. Isoproterenol instigates cardiomyocyte apoptosis and heart failure via AMPK inactivation-mediated endoplasmic reticulum stress. Apoptosis. 2013;18:800-10 pubmed publisher |
- immunocytochemistry; human; 1.5:1000
| Copeland A, Altamura L, Van Deusen N, Schmaljohn C. Nuclear relocalization of polyadenylate binding protein during rift valley fever virus infection involves expression of the NSs gene. J Virol. 2013;87:11659-69 pubmed publisher |
| Klein W, Westendorf C, Schmidt A, Conill-Cortés M, Rutz C, Blohs M, et al. Defining a conformational consensus motif in cotransin-sensitive signal sequences: a proteomic and site-directed mutagenesis study. PLoS ONE. 2015;10:e0120886 pubmed publisher |
| Chapiro J, Sur S, Savic L, Ganapathy-Kanniappan S, Reyes J, Duran R, et al. Systemic delivery of microencapsulated 3-bromopyruvate for the therapy of pancreatic cancer. Clin Cancer Res. 2014;20:6406-17 pubmed publisher |
| Coffey E, Beckel J, Laties A, Mitchell C. Lysosomal alkalization and dysfunction in human fibroblasts with the Alzheimer's disease-linked presenilin 1 A246E mutation can be reversed with cAMP. Neuroscience. 2014;263:111-24 pubmed publisher |
| Watanabe M, Nakatsuka A, Murakami K, Inoue K, Terami T, Higuchi C, et al. Pemt deficiency ameliorates endoplasmic reticulum stress in diabetic nephropathy. PLoS ONE. 2014;9:e92647 pubmed publisher |
| Yang N, Liu Y, Pan C, Sun K, Wei X, Mao X, et al. Pretreatment with andrographolide pills(®) attenuates lipopolysaccharide-induced pulmonary microcirculatory disturbance and acute lung injury in rats. Microcirculation. 2014;21:703-16 pubmed publisher |
| Jing Y, Cui D, Guo W, Jiang J, Jiang B, Lu Y, et al. Activated androgen receptor promotes bladder cancer metastasis via Slug mediated epithelial-mesenchymal transition. Cancer Lett. 2014;348:135-45 pubmed publisher |
| Obri A, Makinistoglu M, Zhang H, Karsenty G. HDAC4 integrates PTH and sympathetic signaling in osteoblasts. J Cell Biol. 2014;205:771-80 pubmed publisher |
| Herrmann M, Lennerz J, Bullinger L, Bartholomae S, Holzmann K, Westhoff M, et al. Transitory dasatinib-resistant states in KIT(mut) t(8;21) acute myeloid leukemia cells correlate with altered KIT expression. Exp Hematol. 2014;42:90-100 pubmed publisher |
| Sweeney E, Fan P, Jordan V. Mechanisms underlying differential response to estrogen-induced apoptosis in long-term estrogen-deprived breast cancer cells. Int J Oncol. 2014;44:1529-38 pubmed publisher |
| Yanagawa Y, Hiraide S, Matsumoto M, Shimamura K, Togashi H. Enhanced transglutaminase 2 expression in response to stress-related catecholamines in macrophages. Immunobiology. 2014;219:680-6 pubmed publisher |
| Hirai S, Endo S, Saito R, Hirose M, Ueno T, Suzuki H, et al. Antitumor effects of a sirtuin inhibitor, tenovin-6, against gastric cancer cells via death receptor 5 up-regulation. PLoS ONE. 2014;9:e102831 pubmed publisher |
| Zhao Y, Ma X, Wang J, Zhu Y, Li R, Wang J, et al. Paeoniflorin alleviates liver fibrosis by inhibiting HIF-1α through mTOR-dependent pathway. Fitoterapia. 2014;99:318-27 pubmed publisher |
| Davidson B, Rosenfeld Y, Holth A, Hellesylt E, Trope C, Reich R, et al. VICKZ2 protein expression in ovarian serous carcinoma effusions is associated with poor survival. Hum Pathol. 2014;45:1520-8 pubmed publisher |
| Voll E, Ogden I, Pavese J, Huang X, Xu L, Jovanovic B, et al. Heat shock protein 27 regulates human prostate cancer cell motility and metastatic progression. Oncotarget. 2014;5:2648-63 pubmed |
| Hu Y, Li S, Yang M, Yan C, Fan D, Zhou Y, et al. Sorcin silencing inhibits epithelial-to-mesenchymal transition and suppresses breast cancer metastasis in vivo. Breast Cancer Res Treat. 2014;143:287-99 pubmed publisher |
| Di Carli M, Tanno B, Capodicasa C, Villani M, Salzano A, Scaloni A, et al. Proteome changes induced by c-myb silencing in human chronic myeloid leukemia cells suggest molecular mechanisms and putative biomarkers of hematopoietic malignancies. J Proteomics. 2014;96:200-22 pubmed publisher |
| Seervi M, Sobhan P, Joseph J, Ann Mathew K, Santhoshkumar T. ERO1α-dependent endoplasmic reticulum-mitochondrial calcium flux contributes to ER stress and mitochondrial permeabilization by procaspase-activating compound-1 (PAC-1). Cell Death Dis. 2013;4:e968 pubmed publisher |
| Arens J, Duong T, Dehmelt L. A morphometric screen identifies specific roles for microtubule-regulating genes in neuronal development of P19 stem cells. PLoS ONE. 2013;8:e79796 pubmed publisher |
| Qi W, Spier C, Liu X, Agarwal A, Cooke L, Persky D, et al. Alisertib (MLN8237) an investigational agent suppresses Aurora A and B activity, inhibits proliferation, promotes endo-reduplication and induces apoptosis in T-NHL cell lines supporting its importance in PTCL treatment. Leuk Res. 2013;37:434-9 pubmed publisher |
| Cawley K, Logue S, Gorman A, Zeng Q, Patterson J, Gupta S, et al. Disruption of microRNA biogenesis confers resistance to ER stress-induced cell death upstream of the mitochondrion. PLoS ONE. 2013;8:e73870 pubmed publisher |
| Gu C, Banasavadi-Siddegowda Y, Joshi K, Nakamura Y, Kurt H, Gupta S, et al. Tumor-specific activation of the C-JUN/MELK pathway regulates glioma stem cell growth in a p53-dependent manner. Stem Cells. 2013;31:870-81 pubmed publisher |
| Xu J, Yao Q, Hou Y, Xu M, Liu S, Yang L, et al. MiR-223/Ect2/p21 signaling regulates osteosarcoma cell cycle progression and proliferation. Biomed Pharmacother. 2013;67:381-6 pubmed publisher |
| Stubbendorff M, Deuse T, Hua X, Phan T, Bieback K, Atkinson K, et al. Immunological properties of extraembryonic human mesenchymal stromal cells derived from gestational tissue. Stem Cells Dev. 2013;22:2619-29 pubmed publisher |
| Okemoto K, Wagner B, Meisen H, Haseley A, Kaur B, Chiocca E. STAT3 activation promotes oncolytic HSV1 replication in glioma cells. PLoS ONE. 2013;8:e71932 pubmed publisher |
| Nishimura T, Zhao X, Gan H, Koyasu S, Remold H. The prostaglandin E2 receptor EP4 is integral to a positive feedback loop for prostaglandin E2 production in human macrophages infected with Mycobacterium tuberculosis. FASEB J. 2013;27:3827-36 pubmed publisher |
| Gebhard A, Jain P, Nair R, Emmons M, Argilagos R, Koomen J, et al. MTI-101 (cyclized HYD1) binds a CD44 containing complex and induces necrotic cell death in multiple myeloma. Mol Cancer Ther. 2013;12:2446-58 pubmed publisher |
| Obitsu S, Sakata K, Teshima R, Kondo K. Eleostearic acid induces RIP1-mediated atypical apoptosis in a kinase-independent manner via ERK phosphorylation, ROS generation and mitochondrial dysfunction. Cell Death Dis. 2013;4:e674 pubmed publisher |
| Linke R, Pries R, Könnecke M, Bruchhage K, Böscke R, Gebhard M, et al. Glycogen synthase kinase 3 in chronic rhinosinusitis: two faces of a single enzyme in one disease. Ann Allergy Asthma Immunol. 2013;110:101-6 pubmed publisher |
| Perez-Pinera P, Ousterout D, Brunger J, Farin A, Glass K, Guilak F, et al. Synergistic and tunable human gene activation by combinations of synthetic transcription factors. Nat Methods. 2013;10:239-42 pubmed publisher |
| Jiang Y, Rumble J, Gleixner A, Unnithan A, Pulugulla S, Posimo J, et al. N-Acetyl cysteine blunts proteotoxicity in a heat shock protein-dependent manner. Neuroscience. 2013;255:19-32 pubmed publisher |
| Bhowmick R, Halder U, Chattopadhyay S, Chanda S, Nandi S, Bagchi P, et al. Rotaviral enterotoxin nonstructural protein 4 targets mitochondria for activation of apoptosis during infection. J Biol Chem. 2012;287:35004-20 pubmed publisher |
| Van de Wouwer M, Couzinié C, Serrano-Palero M, Gonzalez-Fernandez O, Galmés-Varela C, Menéndez-Antolí P, et al. Activation of the BRCA1/Chk1/p53/p21(Cip1/Waf1) pathway by nitric oxide and cell cycle arrest in human neuroblastoma NB69 cells. Nitric Oxide. 2012;26:182-91 pubmed publisher |
| Qi W, Liu X, Cooke L, Persky D, Miller T, Squires M, et al. AT9283, a novel aurora kinase inhibitor, suppresses tumor growth in aggressive B-cell lymphomas. Int J Cancer. 2012;130:2997-3005 pubmed publisher |
| Okamoto M. Immunoreactivity of the amino-terminal portion of the amyloid-beta precursor protein in the nucleolus. Neurosci Lett. 2012;521:82-7 pubmed publisher |
| Yang S, Wang C. The intraflagellar transport protein IFT80 is required for cilia formation and osteogenesis. Bone. 2012;51:407-17 pubmed publisher |
| Gupta S, Deepti A, Deegan S, Lisbona F, Hetz C, Samali A. HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1alpha-XBP1 signaling through a physical interaction. PLoS Biol. 2010;8:e1000410 pubmed publisher |
| Ye Y, Gao J, Tian H, Yearsley K, Lange A, Robertson F, et al. Early to intermediate steps of tumor embolic formation involve specific proteolytic processing of E-cadherin regulated by Rab7. Mol Cancer Res. 2012;10:713-26 pubmed publisher |
| Li H, Panina S, Kaur A, Ruano M, Sánchez-González P, la Cour J, et al. Regulation of the ligand-dependent activation of the epidermal growth factor receptor by calmodulin. J Biol Chem. 2012;287:3273-81 pubmed publisher |
| Li M, Kao E, Gao X, Sandig H, Limmer K, Pavon-Eternod M, et al. Codon-usage-based inhibition of HIV protein synthesis by human schlafen 11. Nature. 2012;491:125-8 pubmed publisher |
| de Lartigue G, Barbier de la Serre C, Espero E, Lee J, Raybould H. Leptin resistance in vagal afferent neurons inhibits cholecystokinin signaling and satiation in diet induced obese rats. PLoS ONE. 2012;7:e32967 pubmed publisher |
| De Raedt T, Walton Z, Yecies J, Li D, Chen Y, Malone C, et al. Exploiting cancer cell vulnerabilities to develop a combination therapy for ras-driven tumors. Cancer Cell. 2011;20:400-13 pubmed publisher |
