product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
ROS1 (D4D6) Rabbit mAb
catalog :
3287
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
D4D6
reactivity :
human, mouse
application :
western blot, flow cytometry
citations: 10
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 3a
Ogura H, Nagatake Kobayashi Y, Adachi J, Tomonaga T, Fujita N, Katayama R. TKI-addicted ROS1-rearranged cells are destined to survival or death by the intensity of ROS1 kinase activity. Sci Rep. 2017;7:5519 pubmed publisher
  • western blot; human; loading ...; fig 1b
Vaishnavi A, Schubert L, Rix U, Marek L, Le A, Keysar S, et al. EGFR Mediates Responses to Small-Molecule Drugs Targeting Oncogenic Fusion Kinases. Cancer Res. 2017;77:3551-3563 pubmed publisher
Jin Y, Sun P, Park S, Kim H, Park E, Kim G, et al. Frequent aerogenous spread with decreased E-cadherin expression of ROS1-rearranged lung cancer predicts poor disease-free survival. Lung Cancer. 2015;89:343-9 pubmed publisher
Jin Y, Sun P, Kim H, Park E, Shim H, Jheon S, et al. ROS1 gene rearrangement and copy number gain in non-small cell lung cancer. Virchows Arch. 2015;466:45-52 pubmed publisher
Cha Y, Lee J, Kim H, Lim S, Cho B, Lee C, et al. Screening of ROS1 rearrangements in lung adenocarcinoma by immunohistochemistry and comparison with ALK rearrangements. PLoS ONE. 2014;9:e103333 pubmed publisher
Mescam Mancini L, Lantuejoul S, Moro Sibilot D, Rouquette I, Souquet P, Audigier Valette C, et al. On the relevance of a testing algorithm for the detection of ROS1-rearranged lung adenocarcinomas. Lung Cancer. 2014;83:168-73 pubmed publisher
Yoshida A, Tsuta K, Wakai S, Arai Y, Asamura H, Shibata T, et al. Immunohistochemical detection of ROS1 is useful for identifying ROS1 rearrangements in lung cancers. Mod Pathol. 2014;27:711-20 pubmed publisher
Sholl L, Sun H, Butaney M, Zhang C, Lee C, Janne P, et al. ROS1 immunohistochemistry for detection of ROS1-rearranged lung adenocarcinomas. Am J Surg Pathol. 2013;37:1441-9 pubmed publisher
Matsuura S, Shinmura K, Kamo T, Igarashi H, Maruyama K, Tajima M, et al. CD74-ROS1 fusion transcripts in resected non-small cell lung carcinoma. Oncol Rep. 2013;30:1675-80 pubmed publisher
Rimkunas V, Crosby K, Li D, Hu Y, Kelly M, Gu T, et al. Analysis of receptor tyrosine kinase ROS1-positive tumors in non-small cell lung cancer: identification of a FIG-ROS1 fusion. Clin Cancer Res. 2012;18:4449-57 pubmed publisher
product information
SKU :
3287P
Product-Name :
ROS1 (D4D6) Rabbit mAb
Size :
40 ul
Price-(USD) :
220 USD
Species-x-Reactivity :
H
Applications :
Flow cytometry
Product-Category :
RTK
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
258, 110, 50-80
Host :
Rabbit
Target :
Ros
Primary-Protein :
ROS
Alt-Names :
MCF3,Proto-oncogene tyrosine-protein kinase ROS,ROS,ROS1,c-ros oncogene 1 , receptor tyrosine kinase,c-ros-1,proto-oncogene c-ros-1 protein,transmembrane tyrosine-specific protein kinase,v-ros UR2 sarcoma virus oncogene homolog 1,v-ros avian UR2 sarcoma virus oncogene homolog 1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.