product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
FAK Antibody
catalog :
3285P
quantity :
40 ul
price :
123 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse, rat, cow, zebrafish
application :
western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 11
Published Application/Species/DilutionReference
  • western blot; human; 1:1000
Webber P, Park C, Qui M, Ramalingam S, Khuri F, Fu H, et al. Combination of heat shock protein 90 and focal adhesion kinase inhibitors synergistically inhibits the growth of non-small cell lung cancer cells. Oncoscience. 2015;2:765-76 pubmed
  • immunohistochemistry; zebrafish; 1:50
Lam P, Mangos S, Green J, Reiser J, Huttenlocher A. In vivo imaging and characterization of actin microridges. PLoS ONE. 2015;10:e0115639 pubmed publisher
  • western blot; human; 1:1000
Pelillo C, Bergamo A, Mollica H, Bestagno M, Sava G. Colorectal Cancer Metastases Settle in the Hepatic Microenvironment Through α5β1 Integrin. J Cell Biochem. 2015;116:2385-96 pubmed publisher
  • western blot; rat; 1:1000
Mills R, Mita M, Nakagawa J, Shoji M, Sutherland C, Walsh M. A role for the tyrosine kinase Pyk2 in depolarization-induced contraction of vascular smooth muscle. J Biol Chem. 2015;290:8677-92 pubmed publisher
  • western blot; human; 1:1000; fig s7
  • immunoprecipitation; human; fig s7
Karginov A, Tsygankov D, Berginski M, Chu P, Trudeau E, Yi J, et al. Dissecting motility signaling through activation of specific Src-effector complexes. Nat Chem Biol. 2014;10:286-90 pubmed publisher
  • western blot; human; fig 1
Potthoff E, Franco D, D'Alessandro V, Starck C, Falk V, Zambelli T, et al. Toward a rational design of surface textures promoting endothelialization. Nano Lett. 2014;14:1069-79 pubmed publisher
  • western blot; rat; 1:1000
Bhattachariya A, Turczynska K, Grossi M, Nordström I, Buckbinder L, Albinsson S, et al. PYK2 selectively mediates signals for growth versus differentiation in response to stretch of spontaneously active vascular smooth muscle. Physiol Rep. 2014;2: pubmed publisher
  • western blot; human
Lu G, Zhang Q, Huang Y, Song J, Tomaino R, Ehrenberger T, et al. Phosphorylation of ETS1 by Src family kinases prevents its recognition by the COP1 tumor suppressor. Cancer Cell. 2014;26:222-34 pubmed publisher
Shaw A, Pickup M, Chytil A, Aakre M, Owens P, Moses H, et al. TGFβ signaling in myeloid cells regulates mammary carcinoma cell invasion through fibroblast interactions. PLoS ONE. 2015;10:e0117908 pubmed publisher
Zaytseva Y, Rychahou P, Gulhati P, Elliott V, Mustain W, O'Connor K, et al. Inhibition of fatty acid synthase attenuates CD44-associated signaling and reduces metastasis in colorectal cancer. Cancer Res. 2012;72:1504-17 pubmed publisher
Fu X, Goglia L, Sanchez A, Flamini M, Giretti M, Tosi V, et al. Progesterone receptor enhances breast cancer cell motility and invasion via extranuclear activation of focal adhesion kinase. Endocr Relat Cancer. 2010;17:431-43 pubmed publisher
product information
SKU :
3285P
Product-Name :
FAK Antibody
Size :
40 ul
Price-(USD) :
123 USD
Species-x-Reactivity :
H, M, R, Mk, B, Pg, (C)
Applications :
Immunohistochemistry (Paraffin)
Product-Category :
Adhesion/ECM
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
125
Host :
Rabbit
Target :
FAK
Primary-Protein :
FAK
Alt-Names :
FADK,FADK 1,FAK,FAK-related non-kinase polypeptide,FAK1,FRNK,Focal adhesion kinase 1,PTK2,PTK2 protein tyrosine kinase 2,Protein-tyrosine kinase 2,pp125FAK
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.