GβL (86B8) Rabbit mAb | Cell Signaling Technology 3274 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

GβL (86B8) Rabbit mAb

catalog :

3274

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

86B8

reactivity :

human, mouse, rat

application :

western blot, immunoprecipitation, western blot knockout validation

more info or order :

Cell Signaling Technology product webpage

citations: 14

Published Application/Species/Sample/Dilution	Reference
western blot knockout validation; mouse; 1:1000; loading ...	Wang B, Jie Z, Joo D, Ordureau A, Liu P, Gan W, et al. TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling. Nature. 2017;545:365-369 pubmed publisher
western blot; human; loading ...; fig 5b	Xu Q, Ge Q, Zhou Y, Yang B, Yang Q, Jiang S, et al. MELK promotes Endometrial carcinoma progression via activating mTOR signaling pathway. EBioMedicine. 2020;51:102609 pubmed publisher
immunoprecipitation; human; loading ...; fig s4a	Son S, Park S, Lee H, Siddiqi F, Lee J, Menzies F, et al. Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A. Cell Metab. 2019;29:192-201.e7 pubmed publisher
western blot; human; 1:1000; loading ...; fig 3b	NGUYEN J, Ray C, Fox A, Mendonça D, Kim J, Krebsbach P. Mammalian EAK-7 activates alternative mTOR signaling to regulate cell proliferation and migration. Sci Adv. 2018;4:eaao5838 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 9e	Hussain R, Macklin W. Integrin-Linked Kinase (ILK) Deletion Disrupts Oligodendrocyte Development by Altering Cell Cycle. J Neurosci. 2017;37:397-412 pubmed publisher
western blot; human; loading ...; fig 3a	Su K, Cao J, Tang Z, Dai S, He Y, Sampson S, et al. HSF1 critically attunes proteotoxic stress sensing by mTORC1 to combat stress and promote growth. Nat Cell Biol. 2016;18:527-39 pubmed publisher
western blot; mouse; 1:1000; fig 1	Kim K, Qiang L, Hayden M, Sparling D, Purcell N, Pajvani U. mTORC1-independent Raptor prevents hepatic steatosis by stabilizing PHLPP2. Nat Commun. 2016;7:10255 pubmed publisher
western blot; human; fig 5	Yasuda K, Takahashi M, Mori N. Mdm20 Modulates Actin Remodeling through the mTORC2 Pathway via Its Effect on Rictor Expression. PLoS ONE. 2015;10:e0142943 pubmed publisher
western blot; rat; fig 10	Nishida H, Ikegami A, Kaneko C, Kakuma H, Nishi H, Tanaka N, et al. Dexamethasone and BCAA Failed to Modulate Muscle Mass and mTOR Signaling in GH-Deficient Rats. PLoS ONE. 2015;10:e0128805 pubmed publisher
western blot; human; loading ...; fig 1a	Fonseca B, Zakaria C, Jia J, Graber T, Svitkin Y, Tahmasebi S, et al. La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1). J Biol Chem. 2015;290:15996-6020 pubmed publisher
	Bhalla M, Law D, Dowd G, Ireton K. Host Serine/Threonine Kinases mTOR and Protein Kinase C-? Promote InlB-Mediated Entry of Listeria monocytogenes. Infect Immun. 2017;85: pubmed publisher
	González I, Martin P, Burdsal C, Sloan J, Mager S, Harris T, et al. Leucine and arginine regulate trophoblast motility through mTOR-dependent and independent pathways in the preimplantation mouse embryo. Dev Biol. 2012;361:286-300 pubmed publisher
	Gao D, Inuzuka H, Tan M, Fukushima H, Locasale J, Liu P, et al. mTOR drives its own activation via SCF(?TrCP)-dependent degradation of the mTOR inhibitor DEPTOR. Mol Cell. 2011;44:290-303 pubmed publisher
	Wu M, Liu H, Fannin J, Katta A, Wang Y, Arvapalli R, et al. Acetaminophen improves protein translational signaling in aged skeletal muscle. Rejuvenation Res. 2010;13:571-9 pubmed publisher

product information

SKU :

3274S

Product-Name :

GβL (86B8) Rabbit mAb

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

H, M, R, Mk

Applications :

Immunoprecipitation

Product-Category :

PI3K / Akt Signaling

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

Host :

Rabbit

Target :

GbetaL

Primary-Protein :

LST8

Alt-Names :

G protein beta subunit like,G protein beta subunit-like,GBL,Gable,GbetaL,LST8,MGC111011,MLST8,MTOR associated protein, LST8 homolog (S. cerevisiae),Mammalian lethal with SEC13 protein 8,POP3,Protein GbetaL,TORC subunit LST8,Target of rapamycin complex subunit LST8,WAT1

more info or order :

Cell Signaling Technology product webpage